On the path of time: Temporal motion in typological perspective

The Moving Ego and Moving Time metaphors have provided a fertile testing ground for the psychological reality of space–time metaphors. Despite this, little research has targeted the linguistic patterns used in these two mappings. To fill that gap, the current study uses corpus data to examine the use of motion verbs in two typologically different languages, English and Spanish. We first investigated the relative frequency of the two metaphors. Whereas we observed no difference in frequency in the Spanish data, our findings indicated that in English, Moving Time expressions are more prevalent than are Moving Ego expressions. Second, we focused on the patterns of use of the verbs themselves, asking whether well-known typological patterns in the expression of spatial motion would carry over to temporal motion. Specifically, we examined the frequencies of temporal uses of path and manner verbs in English and in Spanish. Contra the patterns observed in space, we observed a preference for path verbs in both languages, with this preference more strongly evident in English than in Spanish. In addition, our findings revealed greater use of motion verbs in temporal expressions in Spanish compared to English. These findings begin to outline constraints on the aspects of spatial conceptualization that are likely to be reused in the conceptualization of time

Anzia Yezierska

There is a good deal of inaccuracy and mythologizing about the life of Anzia Yezierska. Some of this misinformation was generated by the public relations offices of Hollywood; other misrepresentations resulted from Yezierska’s own obfuscation, especially concerning her age. Yezierska may have been born in 1880 (although the date is disputed), in a Polish-Russian village, the youngest of nine children. She grew up in a poor, Jewish Orthodox family on New York’s Lower East Side. She left elementary school to help support her family, but evidently a burning passion for learning and a desire to make something of herself led her to Columbia University in 1901, where she lied about a high school diploma to gain admittance. She began writing short stories in 1913 about the Jewish ghetto. The success of her short story collection, Hungry Hearts, published in 1920, led to an offer from Samuel Goldwyn for the motion picture rights and a chance to work on the screenplay in Hollywood. She was offered $10,000 and dubbed “the sweatshop Cinderella,” a phrase created by Howard Dietz, a publicist at the Goldwyn studios

Geographical proximity and circulation of knowledge through inter-firm cooperation

The production of scientific and technological innovations has become essential for many firms, but the latter are seldom in possession of all the knowledge needed for this activity because of the increasing complexity of knowledge bases or because R&D departments are too small. As they do not possess internally all the skills they need, firms wishing to innovate have recourse to external sources, such as cooperation with other firms or public organizations of research. However, acquiring external knowledge is not sufficient; one must also be able to use it in a specific process of production, to transform it into organizational routines, because it is important not only to integrate this knowledge, but ideally to use it to produce new knowledge. This process of creation, re-creation or imitation of new resources not only necessitates several technical and organizational adaptations, but also requires frequent relations of cooperation and partnership. The integration of new knowledge cannot be done in one go, but progressively during the course of the innovation projects, which implies that relations be sustained for a period of time. But the interests of the participants to this interactive process, as well as their opinions concerning technical issues sometimes vary or diverge. This is why co-operations are also sources of tensions and conflicts that jeopardize the adaptation of knowledge produced somewhere else to the context of the firm or even completely hinder the innovation process. In this paper, we try to provide some answers to the following question: What is the role played by geographical and organized proximities in the context of these external acquisitions of knowledge? In other words, can they help reduce the intensity of conflicts and thus facilitate the interactive process of innovations? First, we present shortcomings of innovation theory and works on spillovers claiming the importance of geographical proximity for circulation of knowledge without considering organizational prerequisites to reach this impact. Having explained the relevance of permanent as well as temporary geographical proximity, we will then turn to a discussion of conflicts between cooperators within innovation processes from a theoretical as well as an empirical perspective. The empirical study is based on a case study of French biotechnology firms and will serve to prove our hypothesis that temporary geographical proximity play an important role in preventing and resolving conflicts between innovators.

Editorial: Special Issue “Innovative Techniques and Approaches in the Control and Prevention of Rabies Virus”

Rabies is an ancient lethal scourge that has plagued humankind for centuries. Globally, 60,000 human deaths are estimated to occur each year from rabies virus (RABV) transmission in domestic dogs, mostly affecting children. While rabies is recognized as a neglected disease, there is cause for optimism in the context of growing global recognition, collaboration and commitment to advance a tripartite agenda to eliminate human deaths transmitted from rabid dogs by 2030, also known as “Zero By Thirty” (ZBT). Nevertheless, the ZBT goal must also confront competing challenge(s) of tracking and mitigating human morbidity and mortality during a global pandemic caused by a viral zoonosis with likely origins from one or more wildlife reservoirs. In this context, the concept of One Health has never been more relevant and symbolic as demonstrated with prevention, control and elimination to end human rabies deaths through the mass vaccination of domestic and wild animal reservoir populations

Influence of Pitch Height on the Perception of Submissiveness and Threat in Musical Passages

Bolinger, Ohala, Morton and others have established that vocal pitch height is perceived to be associated with social signals of dominance and submissiveness: higher vocal pitch is associated with submissiveness, whereas lower vocal pitch is associated with social dominance. An experiment was carried out to test this relationship in the perception of non-vocal melodies. Results show a parallel situation in music: higher-pitched melodies sound more submissive (less threatening) than lower-pitched melodies

Susceptibility of Malassezia pachydermatis to azole antifungal agents evaluated by a new broth microdilution method

Malassezia pachydermatis   is considered an opportunistic pathogen of the outer ear duct in dogs and cats. This yeast can also be found in the skin, rectum, anal sacks and vagina. Eighty-two samples of this yeast isolated from dogs with the symptoms of external otitis from the Porto Alegre region were tested for their susceptibility to antifungal agents using the Broth Microdilution Method. The testing antifungal agents were Ketoconazole, Fluconazole and Itraconazole. Experimental essays determined that Sabouraud dextrose broth supplemented with 1% Tween 80 was the most appropriate medium for culture, for a ten-fold dilutions for the inocula, and 48 hours as the interval of readings. The ranges of the Minimal Inhibitory Concentrations (MICs) for the 82 samples were (a) Ketoconazole, from 0.015 to 0.25 mg/mL (mean of 0.08 mg/mL), (b) Fluconazole, from 1 to 32 mg/mL (mean of 9.22 mg/mL), and (c) Itraconazole, from 0.007 to 0.125 mg/mL (mean of 0.05 mg/mL). The isolates of M. pachydermatis showed an excellent level of susceptibility to antifungal azole agents, with all strains being susceptible to Itraconazole, and with only 2.4 % and 3.7% being resistant to Fluconazole and Kketoconazole, respectively. The use of the broth microdilution method allows the assessment of the susceptibility of large numbers of samples from M. pachydermatis isolates to the most common antifungal agents. The proposed procedure is easy to perform and considerably inexpensive compared with other existing tests, which makes this a method of choice for laboratorial use. A standardization of procedures currently used in veterinary mycology laboratories is required. Consistent results among laboratories could greatly benefit the establishment of proper comparisons between studies on antifungal susceptibility and therapeutic trials

Three Cases of Canine Dermatomyositis-Like Disease

Background: Dermatomyositis is an idiopathic, inflammatory/immunemediated disease of the skin, muscles and bloodvessels of hereditary nature and unclear pathogenesis. This familial disease has been described in certain breeds, especially collies and Shetland sheep dogs and is of rare occurrence in mongrel dogs. To describe and discuss three clinical cases of dermatomyositis-like disease and provide a brief review of the literature.Cases: Three young mongrel dogs are included in this report. Case 1: Mandarino, a 4-year-old mongrel dog, having a history of skin lesions for at least a year. Showed an underweight patient, skin ulcers, crusts, alopecia, peri-ocular scarring causing severe lagophthalmia and a corneal ulcer. Muscle atrophy was most notable in the head and legs; the dog haddifficulty and pain walking. Treatment was initialised with cephalexin 30 mg/kg BID, pentoxifylline 25 mg/kg BID, and prednisone 2.2 mg/kg SID. The patient was presented after two weeks for follow up; the anaemia and skin condition had improved, the weight had increased by 2 kg, dysphagia and locomotor abnormalities were not present. Case 2: Milagros,a mongrel female dog approximately two years of age, rescued from a shelter. Physical examination showed facial alopecia, erythema and scarring of the periocular skin, crusting and scaling in alopecic areas, pinnae tip necrosis and crusting, ear alopecia, tail tip necrosis and crusting. Also present were distal limb alopecia, crusting and ulcers in areas of trauma in the hock and carpal surfaces; some nails presented onychorhexis and onychoschizia. The patient has been treated for12 months with a good clinical outcome, with pentoxifylline, azathioprine 2.2 mg/kg EOD alternating with prednisone 1 mg/kg EOD. Case 3: Chuchito, an 11-month-old male mongrel rescued dog had been previously hospitalised due to his skin condition. Physical examination showed depigmented and alopecic areas in the nasal planum, perioral and periocular areas, and inflammation of the palpebral tissues. Necrosis of the distal pinnae, alopecia and scales were evident, along with sloughing of scales and ulcers. Skin lesions were also present in the distal limbs, and alopecia, erythema and some crusting and scales in the carpal, tarsal and digital areas. Onychodystrophy was present in several digits. This study describes the physical examination and the clinical pathological findings, including skin scrapings, fungal cultures, and skin biopsies, in three dogs with dermatomyositis-like disease, as well as the clinical outcomes after slightly different treatment protocols were used. The biopsy results of two dogs showed ischaemic dermatopathy.Discussion: The most common initial signs of the disease are erythema, desquamation and alopecia in the facial area, ears, distal limbs and pinnae in young puppies aged between two and six months of age, followed by pigmentary changes. Muscular lesions are uncommon; when present, they represent the most severe form of this disease. Dysphagia is a common sign and mega-oesophagus may be present. Patients with muscular disease can manifest difficulty walking, with a stiff high gait. The immune mediated pathogenesis of dermatomyositis can relate to triggering factors in some dogs, such as drugs, infections, paraneoplasms, or toxins. Other potential inducing stressors include oestrus, whelping and excessive solar exposure. Dermatomyositis-like or familiar dermatomyositis is diagnosed using clinical findings, histopathologyof skin and muscle, and muscle physiology studies. Electromyography, breed predisposition and genetic background can be helpful in some cases. The clinical findings and response to the treatment of all three cases were compatible with dermatomyositis-like disease in mongrel dogs.Keywords: dermatomyositis, dermatopathy, vascular disease, inflammatory myopathies, mongrel dog

Facial Expression and Vocal Pitch Height: Evidence of an Intermodal Association

Forty-four participants were asked to sing moderate, high, and low pitches while their faces were photographed. In a two-alternative forced choice task, independent judges selected the high-pitch faces as more friendly than the low-pitch faces. When photographs were cropped to show only the eye region, judges still rated the high-pitch faces friendlier than the low-pitch faces. These results are consistent with prior research showing that vocal pitch height is used to signal aggression (low pitch) or appeasement (high pitch). An analysis of the facial features shows a strong correlation between eyebrow position and sung pitch—consistent with the role of eyebrows in signaling aggression and appeasement. Overall, the results are consistent with an inter-modal linkage between vocal and facial expressions

The linguistics of gender

This chapter explores grammatical gender as a linguistic phenomenon. First, I define gender in terms of agreement, and look at the parts of speech that can take gender agreement. Because it relates to assumptions underlying much psycholinguistic gender research, I also examine the reasons why gender systems are thought to emerge, change, and disappear. Then, I describe the gender system of Dutch. The frequent confusion about the number of genders in Dutch will be resolved by looking at the history of the system, and the role of pronominal reference therein. In addition, I report on three lexical- statistical analyses of the distribution of genders in the language. After having dealt with Dutch, I look at whether the genders of Dutch and other languages are more or less randomly assigned, or whether there is some system to it. In contrast to what many people think, regularities do indeed exist. Native speakers could in principle exploit such regularities to compute rather than memorize gender, at least in part. Although this should be taken into account as a possibility, I will also argue that it is by no means a necessary implication

Inclusive Innovation: A Panacea to Developmental Challenges for Africa

Challenges hampering development in Africa abound. Constraints were imposed by the hostile international economic and political order within which Africa’s economies operate; there are domestic weaknesses derived from socio-economic and political structures and neo-liberal structural adjustment policies. Many people are still living in extreme poverty, income inequality within and among many countries have been rising; at the same time, unsustainable consumption and production patterns have resulted in huge economic and social costs and may endanger life on the continent. Gender inequality, climate change, environmental destruction, food insecurity, spread of HIV/AIDS, bad governance, poor access to basic services, such as education, health and sanitation among others are some of the critical development challenges rampant in Africa. Surmounting these development challenges will require an inclusive innovation as a panacea to deliver on the legitimate aspiration towards further economic and social progress, requiring growth and employment, and at the same time strengthening environmental protection in Africa. Inclusive innovation as a panacea to development challenges for Africa forms the nucleus of this paper. This paper is predominantly based on information derived from secondary sources. It recommends that the role of the African heads of state and government should be to facilitate, support, incentivize and leverage the strengths of all stakeholders in order to create sustainable inclusive innovative solutions with significant outreach at maximum efficiency with the least possible burden on the public resources. Keywords: inclusive, innovation, inclusive innovation, panacea, development