Exploring the impact of Instagram like visibility on self-confidence

Background: Instagram allegedly hid the number of likes due to its alleged negative effect. However, it now allows users to choose their visibility settings. Users can either hide or show the number of likes, which has become a conversation topic among users. Some users responded positively, while others had less favorable responses. Moreover, because they consider the “like” feature one of Instagram’s key differentiators, some users hide the number of likes while others continue to display them. Purpose: This study explores users’ choices in configuring Instagram-like settings and their underlying motivations. Additionally, the study also examines the role of Instagram-Likes in boosting self-confidence. Method: This research used a quantitative descriptive method involving 703 students from the Communication Science Study Program at Halu Oleo University, Indonesia. The sample consisted of 70 individuals aged 18 to 24. The data analysis used descriptive statistics to provide a general overview of each variable, displayed with a frequency chart. Researchers also used qualitative data for comparative purposes to enhance research results. Result: Most respondents chose to indicate the number of likes, categorizing their motives into neutral, positive, and negative categories. Instagram likes are a relatively insignificant aspect of life. On the positive side, they can offer benefits to users, such as validation and recognition. Conversely, flaunting one’s likes can be viewed as seeking validation or showing off. It is worth noting that some individuals who conceal the visibility of likes do so to safeguard their self-esteem and mental well-being. Another finding from this study is that Instagram-Like can strengthen their self-confidence. Conclusion: Instagram users have complete control over the Instagram-like options that allow them to hide their like count or not. Instagram-Like can increase self-confidence. The consideration of ‘likes’ as a manifestation of praise, appreciation, acceptance, admiration, and love from others is a prevailing sentiment among individuals. Implication: The researchers expect this research will provide new insights into using social media wisely for positive mental health

Information Literacy And Political Conflict In The Whatsapp Group

Conflicts can occur due to lack of information literacy. Political information disseminated through Whatsapp group often creates political conflicts. The purpose of this article is to examine the political conflict that causes members to leave a group on a whatsapp group, as well as other members\u27 reactions in responding to it. The method used is quantitative descriptive analysis. The results showed that the comments given after the members who leave the group, among others: comments on personal leaving groups, comments on conflicts that occur, comments on problems that cause conflict, and comments on social and political conditions that occur. The attitude taken by the respondents who gave comments after the leave group conducted by another WAG members was to provide anticipatory advice that reminded them that there would be no similar events will conduct in the future, in order to maintain a conducive atmosphere in the WAG, and stop the conversation that was supposed to lead to potential conflict

Recurrent Endometrial Cancer: Which Is the Best Treatment? Systematic Review of the Literature

Background: Endometrial cancer is the most common gynaecological tumour in developed countries. The overall rate of relapse has remained unchanged in recent decades. Recurrences occur in approximately 20% of endometrioid and 50% of non-endometrioid cases. The aim of this systematic review is to compare different therapeutic strategies in the treatment of endometrial cancer recurrence to evaluate their prognostic and curative effects based on site and type of recurrence. Methods: This systematic review of literature was conducted in accordance with the PRISMA guidelines. The study protocol was registered on PROSPERO (CRD42020154042). PubMed, Embase, Chocrane and Cinahl databases were searched from January 1995 to September 2021. Five retrospective studies were selected. Results: A total of 3571 studies were included in the initial search. Applying the screening criteria, 299 articles were considered eligible for full-text reading, of which, after applying the exclusion criteria, 4 studies were selected for the final analysis and included in the systematic review. No studies were included for a quantitative analysis. We divided the results according to the location of the recurrence: locoregional recurrence, abdominal recurrence and extra abdominal recurrence. Conclusion: the treatment of choice should be assessed according to the relapse location and to the presence of single or multiple lesions. A crucial role in the decision-making algorithm is also the type of adjuvant treatment received at the time of the first diagnosis

Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies

<p>Abstract</p> <p>Background</p> <p>Osteoporosis-related fractures are a significant public health concern. Interventions that increase detection and treatment of osteoporosis, as well as prevention of fractures and falls, are substantially underutilized. This paper outlines the protocol for a pragmatic randomised trial of a multifaceted community-based care program aimed at optimizing the evidence-based management of falls and fractures in patients at risk.</p> <p>Design</p> <p>6-month randomised controlled study.</p> <p>Methods</p> <p>This population-based study was completed in the Algoma District of Ontario, Canada a geographically vast area with Sault Ste Marie (population 78 000) as its main city. Eligible patients were allocated to an immediate intervention protocol (IP) group, or a delayed intervention protocol (DP) group. The DP group received usual care for 6 months and then was crossed over to receive the interventions. Components of the intervention were directed at the physicians and their patients and included patient-specific recommendations for osteoporosis therapy as outlined by the clinical practice guidelines developed by Osteoporosis Canada, and falls risk assessment and treatment. Two primary outcomes were measured including implementation of appropriate osteoporosis and falls risk management. Secondary outcomes included quality of life and the number of falls, fractures, and hospital admissions over a twelve-month period. The patient is the unit of allocation and analysis. Analyses will be performed on an intention to treat basis.</p> <p>Discussion</p> <p>This paper outlines the protocol for a pragmatic randomised trial of a multi-faceted, community-based intervention to optimize the implementation of evidence based management for patients at risk for falls and osteoporosis.</p> <p>Trial Registration</p> <p>This trial has been registered with clinicaltrials.gov (ID: NCT00465387)</p

Perilaku Pemilihan Makanan dan Pengenalan Anggota Koloni pada Semut Rangrang Oecophylla smaragdina: Food Preference and Nestmate Recognition of Weaver Ants Oecophylla smaragdina

Weaver ants Oecophylla smaragdina are social insects that recognize nestmates using pheromone. This study analyzes the feeding behavior and nestmate recognition of weaver ants in the urban area of three different islands (Sumatra: Baturaja; Java: Banyuwangi; Papua: Sorong). The free ants were placed in the arena composed of chicken meat, sugar, bananas as the baits. Ten trapped ants were also located in the arena to explore the nestmate recognition between the free and the trapped ants. Five types of behaviors, i.e., approach, stalking, communication, competition, and agonistic, were recorded in 6 days. Food preferences were indicated by the number of conduct towards the feeding sites, and nestmate recognition was indicated by approaching the trapped nestmate. The results showed that the percentage of the approach behavior of free ants was the highest in the three islands but had no significant difference between Sumatra and Java and between Java and Sorong (p-value &gt;0.05). However, the study showed significant differences for the other four behaviors observed. As predicted, the percentage of chicken meat foraged by the ants was the highest due to the carnivorous behavior. The free ants showed the nestmate recognition to the trapped ants in all behavior, except competition. &nbsp

High Prevalence of Arcobacter Carriage in Older Subjects with Type 2 Diabetes

Arcobacters are potential pathogens related to diarrheic infections and, rarely, septicaemia. This study evaluated the prevalence of arcobacters in stool samples of subjects with (n = 38) and without (n = 61) type 2 diabetes by using cultural and molecular techniques. Three Arcobacter positive cultures were found, all among diabetic subjects, whereas molecular analysis showed a carriage rate of 79% and 26.2% in subjects with and without type 2 diabetes (P < .001), respectively. The multivariate analysis showed that type 2 diabetes (β = 1.913; 95%CI: 2.378–19.285; P < .0001) and age (β = 1.744; 95%CI: 2.077–15.766; P = .001) were the only factors independently associated with arcobacters colonization in this population. Our study demonstrated a high prevalence of arcobacters colonization in type 2 diabetic and older subjects. The clinical significance and the potential health risk associated with these emerging species remain to be determined

Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice

Absence of leptin has been associated with reduced skeletal muscle mass in leptin-deficient ob/ob mice. The aim of our study was to examine the effect of leptin on the catabolic and anabolic pathways regulating muscle mass. Gastrocnemius, extensor digitorum longus and soleus muscle mass as well as fiber size were significantly lower in ob/ob mice compared to wild type littermates, being significantly increased by leptin administration (P<0.001). This effect was associated with an inactivation of the muscle atrophy-related transcription factor forkhead box class O3 (FoxO3a) (P<0.05), and with a decrease in the protein expression levels of the E3 ubiquitin-ligases muscle atrophy F-box (MAFbx) (P<0.05) and muscle RING finger 1 (MuRF1) (P<0.05). Moreover, leptin increased (P<0.01) protein expression levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), a regulator of muscle fiber type, and decreased (P<0.05) myostatin protein, a negative regulator of muscle growth. Leptin administration also activated (P<0.01) the regulators of cell cycle progression proliferating cell nuclear antigen (PCNA) and cyclin D1, and increased (P<0.01) myofibrillar protein troponin T. The present study provides evidence that leptin treatment may increase muscle mass of ob/ob mice by inhibiting myofibrillar protein degradation as well as enhancing muscle cell proliferation

Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry

Background and purpose: Prospectively collected data comparing the safety and effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective was to directly compare the effectiveness and safety of NOACs in patients with newly diagnosed atrial fibrillation (AF). Methods: In GLORIA-AF, a large, prospective, global registry program, consecutive patients with newly diagnosed AF were followed for 3&nbsp;years. The comparative analyses for (1) dabigatran vs rivaroxaban or apixaban and (2) rivaroxaban vs apixaban were performed on propensity score (PS)-matched patient sets. Proportional hazards regression was used to estimate hazard ratios (HRs) for outcomes of interest. Results: The GLORIA-AF Phase III registry enrolled 21,300 patients between January 2014 and December 2016. Of these, 3839 were prescribed dabigatran, 4015 rivaroxaban and 4505 apixaban, with median ages of 71.0, 71.0, and 73.0&nbsp;years, respectively. In the PS-matched set, the adjusted HRs and 95% confidence intervals (CIs) for dabigatran vs rivaroxaban were, for stroke: 1.27 (0.79–2.03), major bleeding 0.59 (0.40–0.88), myocardial infarction 0.68 (0.40–1.16), and all-cause death 0.86 (0.67–1.10). For the comparison of dabigatran vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 1.16 (0.76–1.78), myocardial infarction 0.84 (0.48–1.46), major bleeding 0.98 (0.63–1.52) and all-cause death 1.01 (0.79–1.29). For the comparison of rivaroxaban vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 0.78 (0.52–1.19), myocardial infarction 0.96 (0.63–1.45), major bleeding 1.54 (1.14–2.08), and all-cause death 0.97 (0.80–1.19). Conclusions: Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death. Registration: URL: https://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007. Date of registration: September 2013