Kult, Konflikt und Konversion

Abstract Torgrim Eggen’s Hilal (1995) is an early example of literature on the subject of Islam in Norway in its global contexts. As a romantic love story with elements of an action thriller and science fiction in form of future technological inventions, the novel combines an intense reading experience with thought provoking reflections on the role of religion and religious conflicts in secular societies. Based on Almuth Hammer’s ideas on the relationship between religion and literature as well as Jan Assmann’s theses on functions of oral and written language in religions, my essay analyzes the representation of Islam in Hilal and shows parallels between the structure of love and faith in the novel.</jats:p

Increased Expression of PLS3 Correlates with Better Outcome in Sézary Syndrome.

Dermatology-oncolog

Narrative Delikatessen : kulturelle Dimensionen von Ernährung

Die im ersten Band der neuen "Schriftenreihe für Kulturökologie und Literaturdidaktik" versammelten "Narrativen Delikatessen" eröffnen ein breites Spektrum kultureller Dimensionen von Ernährung und stecken damit ein neues Forschungsgebiet ab, das im Zuge globaler Ernährungskrisen von immer größerer Relevanz ist. Die Beiträge untersuchen literarische, mediale und künstlerische Darstellungen von Ernährung in diachroner und synchroner Perspektive und legen komplexe Wechselwirkungen zwischen gesellschaftlichen und ästhetisch transformierten Diskursen offen. Dezidierte Mikroanalysen einzelner Texte stehen dabei neben überblicksartigen Untersuchungen zu spezifischen Motiven oder kulturellen Konstanten in der Inszenierung von Essen. Durch interdisziplinäre Verschränkungen gehen die Betrachtungen über den literaturwissenschaftlichen Tellerrand hinaus und erweitern die Forschungsperspektiven zum Themenkomplex Ernährung auf vielfältige Weise

Primary tumor–derived systemic nANGPTL4 inhibits metastasis

Primary tumors and distant site metastases form a bidirectionally communicating system. Yet, the molecular mechanisms of this crosstalk are poorly understood. Here, we identified the proteolytically cleaved fragments of angiopoietin-like 4 (ANGPTL4) as contextually active protumorigenic and antitumorigenic contributors in this communication ecosystem. Preclinical studies in multiple tumor models revealed that the C-terminal fragment (cANGPTL4) promoted tumor growth and metastasis. In contrast, the N-terminal fragment of ANGPTL4 (nANGPTL4) inhibited metastasis and enhanced overall survival in a postsurgical metastasis model by inhibiting WNT signaling and reducing vascularity at the metastatic site. Tracing ANGPTL4 and its fragments in tumor patients detected full-length ANGPTL4 primarily in tumor tissues, whereas nANGPTL4 predominated in systemic circulation and correlated inversely with disease progression. The study highlights the spatial context of the proteolytic cleavage-dependent pro- and antitumorigenic functions of ANGPTL4 and identifies and validates nANGPTL4 as a novel biomarker of tumor progression and antimetastatic therapeutic agent