8 research outputs found

    Protection of the 13 T Nb3Sn Fresca II dipole

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    The EuCARD project aims on construction of a 19 T hybrid dipole; it will be made of a 6 T HTS dipole associated to a 13 T outsert Nb3Sn dipole [1]. This paper reviews the quench analysis and protection of the 13 T Nb3Sn dipole.Comment: 5 pages, Contribution to WAMSDO 2013: Workshop on Accelerator Magnet, Superconductor, Design and Optimization; 15 - 16 Jan 2013, CERN, Geneva, Switzerlan

    Cryogenic Design of the 43 T LNCMI Grenoble Hybrid Magnet

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    AbstractThe association of two inner resistive coils (Polyhelix and Bitter) producing 34.5 T with an outer NbTi superconducting coil producing 8.5 T to obtain a 43 T hybrid magnet is a technical challenge. Accidental failure modes leading to complex electromagnetic behaviors and large transient dynamical forces should be anticipated. These considerations lead to a reinforced design and a thermo-hydraulic strategy to limit the overpressure. The cryostat has been designed with innovative thermo-mechanical supports sustaining the coil at 1.8 K-1200 hPa and the eddy current shield at 30 K, both being possibly overloaded by high dynamic forces in the worst accidental failure case

    Protection of the 6 T YBCO insert in the 13 T Nb3Sn Fresca II dipole

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    In the EuCARD project, we aim to construct a dipole magnet in YBCO producing 6 T in the background field of a 13 T Nb3Sn dipole FRESCA II. This paper reviews the quench analysis and protection of the YBCO coil. In addition, a recommendation for the protection system of the YBCO coil is presented.Comment: 6 pages, Contribution to WAMSDO 2013: Workshop on Accelerator Magnet, Superconductor, Design and Optimization; 15 - 16 Jan 2013, CERN, Geneva, Switzerlan

    A gerophysiology perspective on healthy ageing

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    International audienceImprovements in public health and health care have resulted in significant increases in lifespan globally, but also to a significant increase in chronic disease prevalence. This has led to focus on healthy aging bringing a shift from a pathology centered to an intrinsic capacity and function centered view. In parallel, the emerging field of geroscience has promoted the exploration of the biomolecular drivers of ageing towards a transverse vision by proposing an integrated set of molecular hallmarks. In this review, we propose to take a step further in this direction, highlighting a gerophysiological perspective that considers the notion of homeostasis/allostasis to robustness/fragility respectively. While robustness is associated with homeostasis achieved by an optimal structure/function relationship in all organs, successive repair processes occurring after daily injuries and infections result in accumulation of scar healing leading to progressive tissue degeneration, allostasis and frailty. Considering biological aging as the accumulation of scarring at the level of the whole organism emphasizes three body transverse and shared key elements– mesenchymal stroma cells/immunity/metabolism i.e. SIM and play down parenchyma cells. This SIM tryptich drives tissue and organ fate and appears as a shared and common reservoir to regulate the age-related evolution of body functions. It provides the basis of a gerophysiology perspective, possibly representing a better way to decipher healthy ageing, not only by defining a composite biomarker(s) but also by developing new preventive/curative strategies

    The EuCARD-2 Future Magnets European Collaboration for Accelerator-Quality HTS Magnets

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    EuCARD-2 is a project supported by FP7-European Commission that includes, inter alia, a work-package (WP10) called “Future Magnets.” This project is part of the long term development that CERN is launching to explore magnet technology at 16 T to 20 T dipole operating field, within the scope of a study on Future Circular Colliders. The EuCARD2 collaboration is closely liaising with similar programs for high field accelerator magnets in the USA and Japan. The main focus of EuCARD2 WP10 is the development of a 10 kA-class superconducting, high current density cable suitable for accelerator magnets, The cable will be used to wind a stand-alone magnet 500 mm long and with an aperture of 40 mm. This magnet should yield 5 T, when stand-alone, and will enable to reach a 15 to 18 T dipole field by placing it in a large bore background dipole of 12-15 T. REBCO based Roebel cables is the baseline. Various magnet configurations with HTS tapes are under investigation and also use of Bi-2212 round wire based cables is considered. The paper presents the structure of the collaboration and describes the main choices made in the first year of the program, which has a breadth of five to six years of which four are covered by the FP7 fram

    Dysregulation of germinal centres in autoimmune disease

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