Le fonds Proust au département des Manuscrits de la Bibliothèque nationale de France

Si le temps de la création est du domaine de la génétique des textes – comment, en une quinzaine d’années seulement, de 1908 environ à sa mort en 1922, Marcel Proust a-t-il conçu, écrit, remanié, corrigé et, pour partie, publié le texte d’À la recherche du temps perdu, et selon quelles étapes ? –, le temps de la conservation publique des archives – cinquante ans en 2012 depuis l’arrivée du fonds à la Bibliothèque nationale en 1962 – relève du domaine plus prosaïque de la bibliothéconomie : te..

ATHLETIC: Pseudo Anthropometric Exoskeleton with a Semi Passive Actuation System for Countermeasure

This paper presents the ongoing ESA project ATHLETIC (AstronauT HeaLtH EnhancemenT Integrated Countermeasure) which aims to develop a new approach of integrated countermeasure device in the shape of an exoskeleton. It focuses primarily on the training of the lower limbs, which are the most heavily affected body parts while astronauts are exposed to microgravity. The ATHLETIC system enables High Intense Resistive Training exercises (HIRT), as well as plyometric exercises such as hopping and jumping. Development and validation shall give an answer to the question if exoskeleton technology is suitable for countermeasure in zero gravity and how such a system performs compared to existing countermeasure devices for zero gravity applications

NEX4EX: Novel Exercise Hardware for Exploration

This paper presents the NEX4EX project Novel Exercise Hardware for Exploration, which aims to design, build and validate a full-body countermeasure platform that enables high intensive resistive and plyometric exercise as well as postural control training, and strength training. The NEX4EX exerciser herewith addresses neuromuscular and musculoskeletal deconditioning. The intended use is to improve crew health and fitness maintenance for long-duration space missions beyond ISS lifetime. This will require the system to be multi-purpose / versatile in terms of exercises added to a smaller footprint than systems currently used on ISS. NEX4EX is a novel concept for a novel utilization paradigm given future space exploration-class missions

NEX4EX: Novel Exercise Hardware for Exploration

This paper presents the NEX4EX project Novel Exercise Hardware for Exploration, which aims to design, build and validate a full-body countermeasure platform that enables high intensive resistive and plyometric exercise as well as postural control training, and strength training. The NEX4EX exerciser herewith addresses neuromuscular and musculoskeletal deconditioning. The intended use is to improve crew health and fitness maintenance for long-duration space missions beyond ISS lifetime. This will require the system to be multi-purpose / versatile in terms of exercises added to a smaller footprint than systems currently used on ISS. NEX4EX is a novel concept for a novel utilization paradigm given future space exploration-class missions

Chemical ordering in bimetallic FeCo nanoparticles: From a direct chemical synthesis to application as efficient high-frequency magnetic material

Single-crystalline FeCo nanoparticles with tunable size and shape were prepared by co-decomposing two metal-amide precursors under mild conditions. The nature of the ligands introduced in this organometallic synthesis drastically affects the reactivity of the precursors and, thus, the chemical distribution within the nanoparticles. The presence of the B2 short-range order was evidenced in FeCo nanoparticles prepared in the presence of HDAHCl ligands, combining 57Fe Mössbauer, zero-field 59Co ferromagnetic nuclear resonance (FNR), and X-ray diffraction studies. This is the first time that the B2 structure is directly formed during synthesis without the need of any annealing step. The as-prepared nanoparticles exhibit magnetic properties comparable with the ones for the bulk (Ms = 226 Am2·kg¿1). Composite magnetic materials prepared from these FeCo nanoparticles led to a successful proof-of-concept of the integration on inductor-based filters (27% enhancement of the inductance value at 100 MHz).This work was performed in the frame of TOURS 2015, and the project was supported by the French “Programme de l’économie numérique des Investissements d’Avenir”. We gratefully acknowledge the International Associated Laboratory (LIA)-M2OZART for financial support. Some of the HR-STEM and EELS studies were conducted at the Laboratorio de Microscopias Avanzadas, Instituto de Nanociencia de Aragon, Universidad de Zaragoza, Spain. R.A. gratefully acknowledges the support from the Spanish Ministry of Economy and Competitiveness (MINECO) through project MAT2016-79776-P (AEF/FEDER. UE). In IPCMS Strasbourg, the work was supported by the CNRS LIA “NANOFUNC” and the LABEX NIE (no. ANR-11-LABX-0058_NIE)

Lunar Volatiles Mobile Instrumentation (LUVMI) Project Results

LUVMI is an innovative, low mass, mobile robotic payload designed specifically for operations at the South Pole of the Moon with a range of several kilometres. Over the 2 past years of the project, the key LUVMI scientific instruments (volatiles analyser and volatiles sampler) were successfully developed and validated up to TRL 5-6. In addition, a ground prototype of the LUVMI rover was developed and tested in a series of outdoor trials, in rocky and sandy environments. This rover, with a target dry mass of ~40kg for a flight version, features an adjustable height chassis to adapt to terrain roughness and allowing to bring instruments very closely and precisely to the surface. The locomotion capability of the LUVMI rover was tested in partially representative conditions, as part of the project. This paper reports on the project’s results and lessons learnt, and gives indications of how LUVMI may be further matured to target potential mission slots in the mid-2020s, as part of ESA mission and/or supported by private funding

Meta-analysis of the diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of coronary artery disease

<p>Abstract</p> <p>Aim</p> <p>Evaluation of the diagnostic accuracy of stress perfusion cardiovascular magnetic resonance for the diagnosis of significant obstructive coronary artery disease (CAD) through meta-analysis of the available data.</p> <p>Methodology</p> <p>Original articles in any language published before July 2009 were selected from available databases (MEDLINE, Cochrane Library and BioMedCentral) using the combined search terms of magnetic resonance, perfusion, and coronary angiography; with the exploded term coronary artery disease. Statistical analysis was only performed on studies that: (1) used a [greater than or equal to] 1.5 Tesla MR scanner; (2) employed invasive coronary angiography as the reference standard for diagnosing significant obstructive CAD, defined as a [greater than or equal to] 50% diameter stenosis; and (3) provided sufficient data to permit analysis.</p> <p>Results</p> <p>From the 263 citations identified, 55 relevant original articles were selected. Only 35 fulfilled all of the inclusion criteria, and of these 26 presented data on patient-based analysis. The overall patient-based analysis demonstrated a sensitivity of 89% (95% CI: 88-91%), and a specificity of 80% (95% CI: 78-83%). Adenosine stress perfusion CMR had better sensitivity than with dipyridamole (90% (88-92%) versus 86% (80-90%), P = 0.022), and a tendency to a better specificity (81% (78-84%) versus 77% (71-82%), P = 0.065).</p> <p>Conclusion</p> <p>Stress perfusion CMR is highly sensitive for detection of CAD but its specificity remains moderate.</p

Assessing the Distribution of Water Ice and Other Volatiles at the Lunar South Pole with LUVMI-X: A Mission Concept

The search for exploitable deposits of water and other volatiles at the Moon’s poles has intensified considerably in recent years, due to the renewed strong interest in lunar exploration. With the return of humans to the lunar surface on the horizon, the use of locally available resources to support long-term and sustainable exploration programs, encompassing both robotic and crewed elements, has moved into focus of public and private actors alike. Our current knowledge about the distribution and concentration of water and other volatiles in the lunar rocks and regolith is, however, too limited to assess the feasibility and economic viability of resource-extraction efforts. On a more fundamental level, we currently lack sufficiently detailed data to fully understand the origins of lunar water and its migration to the polar regions. In this paper, we present LUVMI-X, a mission concept intended to address the shortage of in situ data on volatiles on the Moon that results from a recently concluded design study. Its central element is a compact rover equipped with complementary instrumentation capable of investigating both the surface and shallow subsurface of illuminated and shadowed areas at the lunar south pole. We describe the rover and instrument design, the mission’s operational concept, and a preliminary landing-site analysis. We also discuss how LUVMI-X fits into the diverse landscape of lunar missions under development

Préface

Je m’écarte. J’attends avec impatience la partie XVIIIe, les Cabinets intérieurs, celui de la Pendule, l’instrument conçu par Passement qui indique l’heure, le jour, le mois, l’année, le quartier de la lune, le croissant de ma rêverie entrant dans sa dernière phase.[Michel Chaillou, Le Rêve de Saxe] Ouvrir un livre de Michel Chaillou, se lancer dans la lecture, c’est accepter de s’aventurer dans un pays étrange et familier à la fois : un pays dont la géographie, aux repères faussement limpide..