An 11-Year-Old Child with Autosomal Dominant Polycystic Kidney Disease Who Presented with Nephrolithiasis

Patients with autosomal dominant polycystic kidney disease become symptomatic and are diagnosed usually at adulthood. The rate of nephrolithiasis in these patients is 5–10 times the rate in the general population, and both anatomic and metabolic abnormalities play role in the formation of renal stones. However, nephrolithiasis is rare in childhood age group. In this paper, an 11-year-old child with autosomal dominant polycystic kidney disease presenting with nephrolithiasis is discussed

İdiopatik Granülomatöz Mastitte Görüntüleme Bulguları

Amaç: İdiopatik granülomatöz mastit İGM memenin sebebi tam olarak bilinmeyen kronik enflamatuar bir hastalığıdır. Kesin tanısı görüntüleme yöntemlerinin yanı sıra histopatolojik olarak granülomatöz inflamasyonla beraber kronik lobülit saptanması ve diğer etkenlerin dışlanması ile konur. Bu çalışmamızda İGM’nin görüntüleme bulgularını vurgulayarak tanı ve tedavi sürecine nasıl katkı sağlayabileceğini gözden geçirmeyi amaçladık.Gereç ve Yöntem: 2017 Ekim-2019 Mart tarihleri arasında genel cerrahi polikliniğine memede akıntı, kızarıklık, ısı artışı, ele gelen sertlik, meme cildinde yara şikayeti ile başvuran, klinik muayene ve görüntüleme bulguları granulamotöz mastit şüphesi taşıyan ve biyopsi sonucu granulomatöz mastit olarak rapor edilen 57 olgu dahil edildi. 40 yaş altı olgularda Ultrason US ve 40 yaş üstü ise mamografi MG ve /veya US bulguları retrospektif olarak değerlendirildi. Manyetik rezonans görüntüleme MRG yapılan olgularda MRG bulguları da not edildi. Bulgular: MG bulguları non-spesifik ve değişken olmakla birlikte, çoğunlukla rastladığımız bulgu fokal asimetri idi. US’da en sık rastlanan bulgu tubuler uzanım gösteren ve birbirleriyle birleşme eğiliminde olan hipoekoik lezyonlar şeklindeydi. Abse drenajında ve tedavi takibinde de US’nin tekrarlanabilir fonksiyonel bir metod olduğu görüldü. MRG bulguları, meme başı retraksiyonu, ciltte kalınlaşma, kitlesel ve/veya kitlesel olmayan kontrastlanmalar, periferal kontrastlanan abse formasyonları ile aksiller lenf adenopatiler olarak özetlenebilir. Sonuç: İGM nedeni kesin olarak bilinmeyen, kronik enflamatuar bir meme hastalığıdır. Doğru tanı ve uygun tedavi hastaların yaşam kalitesi ve çoğunluğu genç hasta grubunda olması nedeniyle de meme estetiği açısından oldukça önem arz etmektedir. Radyolojik görüntüleme bulguları klinik bulgularla birlikte değerlendirildiğinde tecrübeli kliniklerde hızlı bir şekilde doğru histopatolojik tanıya ulaşılarak tanı ve tedavi sürecine önemli katkıda bulunabilir kanaatindeyi

Preoperative Lipid Profile of Patients Operated For Coronary Bypass Surgery

DergiPark: 379072tmsjAims: Dyslipidemia is a major risk factor for atherosclerosis and coronary heart disease. Evidence showed that an atherogenic lipid pattern is characterized by high levels of small, dense low-density lipoprotein, low levels of high-density lipoprotein cholesterol, elevated triglyceride and total cholesterol levels; similar with the lipid profiles of diabetics.Methods: In this study, 91 patients who underwent coronary artery bypass grafting in Trakya University Hospital Department of Cardiovascular Surgery from April 2017 to September 2017 were analyzed retrospectively. As for statistical analysis, Student’s t-test and Mann Whitney U tests were performed.Results: The lipid profiles of patients were not significantly related to their ages and genders. However, when diabetic patients’ lipid profiles were analyzed, their low-density lipoprotein, and total cholesterol values were found to be significantly lower.Conclusion: It is unexpected to see that patients with diabetes had significantly lower total cholesterol and low-density lipoprotein levels than non-diabetic patients. As for the reason, it is thought that patients with diabetes are more conscious of their health conditio

Bireyleri rekreasyonel egzersize güdüleyen faktörlerin belirlenmesi: demografik farklılıklar

The purpose of this study was to investigate and compare the motivational factors that motivate individuals to the recreational exercise participation with regard to demographic variables. 302 male (55,1%) and 246 female (44,9%) with a total of 548 recreational exercise participants from 9 health and fitness centers, in Ankara, participated voluntarily to this study. “Recreational Exercise Motivation Measure” was used as means of data collection instrument. Independent Samples t-test was used to examine the mean differences with regard to gender and marital status considering 5 subscales. The results of independent samples t-test indicated that, there was a significant mean difference between males and females in “health” and status” (p  Bu çalışmanın amacı, sağlık-spor merkezlerinde rekreasyonel egzersize katılan bireyleri bu etkinliklere güdüleyen faktörlerin belirlenmesi ve katılım nedenlerinin bazı demografik değişkenlere göre karşılaştırılmasıdır. Çalışmaya Ankara İlinde rekreasyonel amaçlı hizmet veren 9 farklı sağlık-spor merkezlerinde egzersiz yapan 302 erkek (%55,1) ve 246 kadın (%44,9) olmak üzere toplam 548 kişi gönüllü olarak katılmıştır. Çalışmada veri toplama aracı olarak 5 alt boyut ve toplam 66 maddeden oluşan “Egzersize Güdülenme Anketi” kullanılmıştır. Araştırmada kullanılan anketin 5 alt boyutunda rekreasyonel egzersiz katılımcılarının, cinsiyet ve medeni hale göre farklılığı test etmek için yapılan independent samples t-test analizi sonuçlarına göre; cinsiyete göre “sağlık” ve “rekabet” alt boyutlarında (p<0,05), medeni hale göre ise, “sağlık” alt boyutu hariç diğer 4 alt boyutta (p<0,05),  anlamlı farklılıklar olduğu tespit edilmiştir. Ayrıca, yapılan ANOVA sonuçlarına göre ise yaş (rekabet ve vücut ve dış görünüm), eğitim durumuna göre (sağlık), istatistiksel olarak anlamlı farklılıklar olduğu tespit edilmiştir (p<0,05). Sonuç olarak, “sağlık”, “beceri gelişimi”, “vücut ve dış görünüm” faktörlerinin bireyleri rekreasyonel egzersize güdülemede ilk 3 sırayı aldığı tespit edilmiştir. &nbsp

Piezo Elektriksel Etki İle Aktive Edilen Dokunmatik Ekranların Titreşim Analizleri

Konferans Bildirisi-- İstanbul Teknik Üniversitesi, Teorik ve Uygulamalı Mekanik Türk Milli Komitesi, 2017Conference Paper -- İstanbul Technical University, Theoretical and Applied Mechanical Turkish National Committee, 2017Taşınabilir elektronik cihazlar üzerindeki dokunmatik ekranlarda genellikle görsel ve işitsel geri bildirimler kullanılmaktadır. Bu cihazlar, gürültülü ve dikkat dağıtıcı ortamlarda kullanıldığı zaman çoğunlukla mevcut geri bildirim yöntemleri yetersiz kalmakta ve cihazın kullanılabilirliği ciddi derecede azalmaktadır. Bu nedenle yeni bir teknolojiye ihtiyaç duyulmaktadır. Dokunmatik ekranlara hareket verilerek parmak uçlarındaki sinirlerin uyarılması ile oluşturulan dokunsal geri bildirimler son zamanlarda bu sektörde önem kazanmaya başlayan konulardan birisidir. Dokunmatik geri bildirim düzeneği için piezo elemanlar kullanılmaktadır. Piezo elemanlar malzeme özellikleri gereği üzerlerine gerilim uygulandığında şekil değiştirmektedirler. Eğer bu zorlama sinüzoidal ise bu aktivasyon ile bağlı oldukları eleman olan ekranı da titreştirmektedirler. Piezo elemanlara mekanik çalışma sınırları içerisinde tüm titreşim fonksiyonları uygulanabilmektedir. Böylelikle kalp atışı, patlama sesi gibi her çeşit titreşim fonksiyonu dokunmatik ekran üzerinde oluşturulabilmektedir. Bu çalışmada sektörde kullanılan farklı tasarım parametrelerine sahip ekran camlarının titreşim mod yapıları incelenmiştir. Ekranın mod yapıları sonlu elemanlar mantığı (SEM) ile çalışan COMSOL programında elde edilmiştir. Bu programda piezo elemanların malzeme ve elektriksel özellikleri dikkate alınmaktadır. Ekran üzerinde en iyi titreşim fonksiyonunu üretebilmek için farklı piezo sayısı ve farklı piezo yerleşimleri için titreşim analizleri COMSOL programı ile karşılaştırılmıştır. Sonuç olarak en iyi titreşim fonksiyonunu üreten tasarım elde edilmiştir.An audiovisual feedback is used on touch screens in portable electronic devices. When these devices are used in noisy and distracting environments, suitable available feedback methods is severely inadequate and the availability of the device severely reduced. For this reason, the users need a new technology. The fingertip nerves are warned by the vibration of the touch screen. Tactile feedback is one of the issues that have recently gained importance in this sector. Piezo elements are used for the touch feedback mechanism. Piezo elements can change shape when the tension applied due to material properties. If this coercion is sinusoidal, the screen, which is the component of those connected by this activation, will also vibrate. All vibration functions can apply to piezo elements within mechanical working limits. Thus, all kinds of vibration functions such as heartbeat, explosion sound can be created on the touch screen. In this study, vibration mode structures of glasses with different design parameters are investigated. The results are obtained with software with COMSOL program. In this program, the material and electrical properties of the piezo elements are taken into account. The vibration analysis for different piezo numbers and different piezo locations were compared with the COMSOL program. As a result, a design that produces the best vibration function is determined

Risk Factors and Management of Hepatitis B Virus Reactivation in Patients With Hematological Disorders

DergiPark: 420829tmsjAims: The aim of this study is to evaluate hepatitis B virus serological status and to categorize the risks of our treatmentmodalities in patients with both benign and malignant hematological disorders.Methods: This was a retrospective study of 552 patients who were admitted to the Trakya University Hospital Hematologyunit between 01.01.2017 and 31.12.2017. All data regarding the diagnosis, treatment and HBV serologicalstatus were collected from patient files. Data were analyzed with IBM SPSS V.20 using descriptive statistical analysis.Results: Hepatitis B surface antigen was positive in 45 (8.2%) patients, antibody to the hepatitis B surface antigenwas positive in 279 (50.5%) patients and antibody to the hepatitis B core antigen was positive in 247 (44.7%) patients.According to these results, 32 patients were found to be vaccinated for hepatitis B virus. Reactivation was observed in4 (0.7%) patients who have been hepatitis B surface antigen positive and have received adequate duration of antiviralprophylaxis with tenofovir. These 4 patients have received monoclonal antibody for immunosuppressive treatment.Conclusion: To conclude, although the rate of hepatitis B surface antigen reactivation is quite low, as many patientsas possible should be vaccinated to reduce the costs of antiviral treatments and monitorization. If there is notime to vaccinate, patients should be categorized according to guidelines by their hepatitis B surface antigen serologicalstatus and by the planned immunosuppressive treatments

How does disease location affect acute phase reactants in ulcerative colitis?

Background: We aimed to evaluate erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), white blood cell (WBC), platelet (PLT) counts and albumin levels according to disease location in ulcerative colitis.Methods: The ESR, CRP, WBC, PLT counts and albumin levels of 206 ulcerative colitis patients with endoscopic activity were retrospectively evaluated. Endoscopic activity had been assessed using Rachmilewitz endoscopic activity index. Patients were grouped according to the extent of disease by Montreal classification, and they were evaluated regarding the location and severity of disease according to the laboratory test results.Results: Among 206 patients, 88 (42.7%) had extensive colitis, 89 (43.2%) of them had left sided colitis and 29 (14%) patients had proctitis. According to the endoscopic activity index, 32.04% of the patients had mild activity, 39.32% moderate activity and 28.64% had severe activity. As the disease extent progressed from the distal to the proximal intestine, CRP, ESR, WBC and PLT counts showed a significant increase while albumin levels showed a significant decrease. In our study, the test that yielded the best results in the assessment of disease activity was CRP, which was found to be high in 80% of patients with extensive colitis, followed by ESR, PLT and WBC counts. As the involved intestine shortened, the rate of patients with abnormal laboratory tests significantly decreasedConclusion: CRP, ESR, WBC, PLT counts and albumin levels are of limited value in determining disease activity in ulcerative colitis patients, especially in those with proctiti

The Effects of Nasal Septum Deviation on Ocular Examination Findings: Does Deviated Nasal Septum Cause Impaired Vision?

Aim: Nasal obstruction due to nasal septum deviation is associated with systemic diseases such as cardiopulmonary disease, neurological and vascular problems. But the effect of pure nasal deviation on the ocular system has not been precisely investigated. The aim of this study was to analyze the association of nasal septal deviation with ocular examination findings. Material and Methods: Twenty-seven adult patients underwent septoplasty and 31 controls were included in the study. The study group was conducted on patients with pure nasal septum deviation which is significantly obstructing the nasal airway (>50%). In ophthalmological examination; peripapillary retinal nerve fiber layer, macular and choroidal thickness measurements were obtained. The examination findings were compared between the study and control groups. Results: The mean macular thicknesses at nasal-500μm were 305.89±32.79 and 287.87±25.00 in the study and control groups, respectively (p=0.021). The mean macular thicknesses at nasal-1000μm were 353.04±21.28 and 341.16±17.97 in the study and control groups, respectively (p=0.025). The mean thickness of choroid was statistically significantly different at central (p=0.036) and peripheral measurements; nasal-500μm (p=0.020); nasal-1000μm (p=0.001); nasal-1500μm (p<0.001); temporal-500μm (p=0.023) and temporal-1000μm (p=0.045). No statistically significant difference was found between the two groups according to ocular tension, thickness of cornea, keratometry, anterior chamber depth, axial length of cornea, and retinal nerve fiber layer thickness. Conclusion: This is one of the pioneer studies evaluating the ocular examination findings in patients with nasal septum deviation. Our results indicate the increased thickness of both macula and choroid in patients with nasal septum deviation