PERANCANGAN SISTEM INFORMASI UNTUK MEREDUKSI KETIDAKPASTIAN WAKTU PENYELESAIAN ORDER DI AL-FATH OFFSET

Waktu penyelesaian order dalam sebuah usaha percetakan menjadi salah satu faktor penting yang dapat mempengaruhi pandangan customer terhadap kinerja dari percetakan tersebut. Ketidakpastian dalam menentukan waktu penyelesaian order menjadi masalah utama yang perlu diselesaikan agar dapat memperbaiki kualitas pada sistem yang digunakan di bagian pemesanan dan penerimaan order. Solusi yang diinginkan oleh pihak usaha percetakan yaitu memperbaiki sistem yang digunakan agar dapat meningkatkan kinerja dari percetakan tersebut. Dalam memenuhi solusi yang diinginkan tersebut yaitu dengan merancang sistem informasi untuk bagian pemesanan dan penerimaan order menggunakan metode System Development Life Cycle Model Waterfall. Perancangan sistem informasi dilakukan menggunakan aplikasi Visual Studio Code dengan framework Bootstrap, serta berbasis PHP dan MySQL sebagai software yang digunakan untuk database. Implementasi sistem informasi yang telah dirancang mempunyai tujuan utama yaitu dengan memberikan penyimpan data yang jelas dan terstruktur untuk order dari customer serta data-data lainnya. Critical Success Factor (CSF) ditentukan menggunakan kuisoner User Acceptance Test (UAT) dengan hasil persentase menjadi acuan terpenuhinya tujuan perancangan sistem informasi. Didapatkan hasil persentase UAT sebesar 93% yang berarti sistem informasi yang dirancang layak dan memenuhi kebutuhan dalam penyelesaian masalah ketidakpastian waktu penyelesaian order. Selain itu, dengan adanya visualisasi grafik mengenai jumlah order yang masuk dan diproses dapat menjadi informasi yang digunakan sebagai decision maker dalam menentukan waktu penyelesaian order untuk pelanggan dengan lebih sesuai

rf-studies of vortex dynamics in isotropic type-II superconductors

We have measured the surface impedance of thick superconductors in the mixed state over a broad 2 kHz - 20 MHz frequency range. The depinning cross-over is observed; but it is much broader than expected from classical theories of pinning. A striking result is the existence of size effects which invalidate the common interpretation of the low-frequency surface inductance in terms of a single penetration depth. Instead, a two-mode description of vortex dynamics, assuming free vortex flow in the bulk and surface pinning, accounts quantitatively for the spectrum of the complex apparent penetration depth.Comment: 20 pages, 6 figures, 28 reference

Eigenvector statistics in non-Hermitian random matrix ensembles

We study statistical properties of the eigenvectors of non-Hermitian random matrices, concentrating on Ginibre's complex Gaussian ensemble, in which the real and imaginary parts of each element of an N x N matrix, J, are independent random variables. Calculating ensemble averages based on the quantity $< L_\alpha | L_\beta >$, where $< L_\alpha |$ and $| R_\beta >$ are left and right eigenvectors of J, we show for large N that eigenvectors associated with a pair of eigenvalues are highly correlated if the two eigenvalues lie close in the complex plane. We examine consequences of these correlations that are likely to be important in physical applications.Comment: 4 pages, no figure

Optically-stimulated desorption of 'hot' excimers from pre-irradiated Ar solids

Electronically-induced desorption from solid Ar pre-irradiated by a low-energy electron beam was investigated by activation spectroscopy methods - photon-stimulated exoelectron emission and photon-stimulated luminescence in combination with spectrally-resolved measurements in the VUV range of the spectrum. Desorption of vibrationally excited argon molecules Ar2^*(v) from the surface of pre-irradiated solid Ar was observed for the first time. It was shown that desorption of 'hot' Ar2^*(v) molecules is caused by recombination of self-trapped holes with electrons released from traps by visible range photons. The possibility of optical stimulation of the phenomenon is evidenced.Comment: The complete version of the paper will be published in Fiz. Nizk. Temp. (Low Temp. Phys.

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.

Accelerating cures for children with cancer remains an immediate challenge as a result of extensive oncogenic heterogeneity between and within histologies, distinct molecular mechanisms evolving between diagnosis and relapsed disease, and limited therapeutic options. To systematically prioritize and rationally test novel agents in preclinical murine models, researchers within the Pediatric Preclinical Testing Consortium are continuously developing patient-derived xenografts (PDXs)-many of which are refractory to current standard-of-care treatments-from high-risk childhood cancers. Here, we genomically characterize 261 PDX models from 37 unique pediatric cancers; demonstrate faithful recapitulation of histologies and subtypes; and refine our understanding of relapsed disease. In addition, we use expression signatures to classify tumors for TP53 and NF1 pathway inactivation. We anticipate that these data will serve as a resource for pediatric oncology drug development and will guide rational clinical trial design for children with cancer

Differences in genotype and virulence among four multidrug-resistant <i>Streptococcus pneumoniae</i> isolates belonging to the PMEN1 clone

We report on the comparative genomics and characterization of the virulence phenotypes of four &lt;i&gt;S. pneumoniae&lt;/i&gt; strains that belong to the multidrug resistant clone PMEN1 (Spain&lt;sup&gt;23F&lt;/sup&gt; ST81). Strains SV35-T23 and SV36-T3 were recovered in 1996 from the nasopharynx of patients at an AIDS hospice in New York. Strain SV36-T3 expressed capsule type 3 which is unusual for this clone and represents the product of an in vivo capsular switch event. A third PMEN1 isolate - PN4595-T23 - was recovered in 1996 from the nasopharynx of a child attending day care in Portugal, and a fourth strain - ATCC700669 - was originally isolated from a patient with pneumococcal disease in Spain in 1984. We compared the genomes among four PMEN1 strains and 47 previously sequenced pneumococcal isolates for gene possession differences and allelic variations within core genes. In contrast to the 47 strains - representing a variety of clonal types - the four PMEN1 strains grouped closely together, demonstrating high genomic conservation within this lineage relative to the rest of the species. In the four PMEN1 strains allelic and gene possession differences were clustered into 18 genomic regions including the capsule, the blp bacteriocins, erythromycin resistance, the MM1-2008 prophage and multiple cell wall anchored proteins. In spite of their genomic similarity, the high resolution chinchilla model was able to detect variations in virulence properties of the PMEN1 strains highlighting how small genic or allelic variation can lead to significant changes in pathogenicity and making this set of strains ideal for the identification of novel virulence determinant

Assessing the Relative Performance of Nurses Using Data Envelopment Analysis Matrix (DEAM)

Assessing employee performance is one of the most important issue in healthcare management services. Because of their direct relationship with patients, nurses are also the most influential hospital staff who play a vital role in providing healthcare services. In this paper, a novel Data Envelopment Analysis Matrix (DEAM) approach is proposed for assessing the performance of nurses based on relative efficiency. The proposed model consists of five input variables (including type of employment, work experience, training hours, working hours and overtime hours) and eight output variables (the outputs are amount of hours each nurse spend on each of the eight activities including documentation, medical instructions, wound care and patient drainage, laboratory sampling, assessment and control care, follow-up and counseling and para-clinical measures, attendance during visiting and discharge suction) have been tested on 30 nurses from the heart department of a hospital in Iran. After determining the relative efficiency of each nurse based on the DEA model, the nurses’ performance were evaluated in a DEAM format. As results the nurses were divided into four groups; superstars, potential stars, those who are needed to be trained effectively and question marks. Finally, based on the proposed approach, we have drawn some recommendations to policy makers in order to improve and maintain the performance of each of these groups. The proposed approach provides a practical framework for hospital managers so that they can assess the relative efficiency of nurses, plan and take steps to improve the quality of healthcare delivery

Origins of direction selectivity in the primate retina

From mouse to primate, there is a striking discontinuity in our current understanding of the neural coding of motion direction. In non-primate mammals, directionally selective cell types and circuits are a signature feature of the retina, situated at the earliest stage of the visual process. In primates, by contrast, direction selectivity is a hallmark of motion processing areas in visual cortex, but has not been found in the retina, despite significant effort. Here we combined functional recordings of light-evoked responses and connectomic reconstruction to identify diverse direction-selective cell types in the macaque monkey retina with distinctive physiological properties and synaptic motifs. This circuitry includes an ON-OFF ganglion cell type, a spiking, ON-OFF polyaxonal amacrine cell and the starburst amacrine cell, all of which show direction selectivity. Moreover, we discovered that macaque starburst cells possess a strong, non-GABAergic, antagonistic surround mediated by input from excitatory bipolar cells that is critical for the generation of radial motion sensitivity in these cells. Our findings open a door to investigation of a precortical circuitry that computes motion direction in the primate visual system.This work was largely supported by grants from the National Eye Institute (NIH NEI) to D.M.D. (EY032045), R.G.S. (EY022070), P.D.G. (EY018369) and by National Institutes of Health (NIH) Grant RR-00166 to the Tissue Distribution Program of the Washington National Primate Research Center (WaNPRC), grant P51 OD010425 from the NIH Office of Research Infrastructure Program to the WaNPRC. and EY01730 to the Vision Research Core at the University of Washington. Additional support from MICINN Programa de Movilidad Salvador de Madariaga (PRX16/00188) to F.V. and NIH (NIBIB) R21EB028069 to J.B.T, and a Christina Enroth-Cugell and David Cugell Fellowship to J.W.Peer reviewe