492 research outputs found

    Fractura-luxación de Galeazzi, con epifisiolisis cubital distal e interposición tendinosa.

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    Una rara variante no descrita de la fractura-luxación de Galeazzi, con afectación de la epífisis del cúbito, cuya reducción estaba impedida por la interposición del tendón Extensor Carpi Ulnaris, (extensor cubital del carpo). Los autores presentan un caso y revisan la literatura, así como su solución quirúrgica y resultado obtenido.An unusual variant of Galeazzi's fracture-luxation involving the distal ulnar epiphysis, whos e reduction was impeded by the interposition of the Extensor Carpi Ulnaris (ECU) tendom. Presentation of a case and revision of the current literature

    Evaluation of EMG processing techniques using Information Theory

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    <p>Abstract</p> <p>Background</p> <p>Electromyographic signals can be used in biomedical engineering and/or rehabilitation field, as potential sources of control for prosthetics and orthotics. In such applications, digital processing techniques are necessary to follow efficient and effectively the changes in the physiological characteristics produced by a muscular contraction. In this paper, two methods based on information theory are proposed to evaluate the processing techniques.</p> <p>Methods</p> <p>These methods determine the amount of information that a processing technique is able to extract from EMG signals. The processing techniques evaluated with these methods were: absolute mean value (AMV), RMS values, variance values (VAR) and difference absolute mean value (DAMV). EMG signals from the middle deltoid during abduction and adduction movement of the arm in the scapular plane was registered, for static and dynamic contractions. The optimal window length (segmentation), abduction and adduction movements and inter-electrode distance were also analyzed.</p> <p>Results</p> <p>Using the optimal segmentation (200 ms and 300 ms in static and dynamic contractions, respectively) the best processing techniques were: RMS, AMV and VAR in static contractions, and only the RMS in dynamic contractions. Using the RMS of EMG signal, variations in the amount of information between the abduction and adduction movements were observed.</p> <p>Conclusions</p> <p>Although the evaluation methods proposed here were applied to standard processing techniques, these methods can also be considered as alternatives tools to evaluate new processing techniques in different areas of electrophysiology.</p

    Land-use changes as a critical factor for long-term wild rabbit conservation in the Iberian Peninsula

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    European rabbits (Oryctolagus cuniculus), a multifunctional keystone species in the Iberian Peninsula, have drastically declined over past decades. Rabbit decline has been frequently attributed to the arrival of two viral diseases. However, decline was apparently ongoing before the arrival of the diseases, as a consequence of habitat loss and fragmentation. In this paper, the effect on rabbit populations of land-use changes during recent decades in Andalusia (southern Spain) is analysed. Areas favourable for rabbits both at present and during the 1960s are identified, and the environmental and land-use factors that determine these areas established. In areas where the favourability for rabbits has changed during recent decades, main land use changes are assessed to identify possible factors explaining rabbit favourability in these areas. Areas favourable to rabbits are currently determined by factors similar to those during the 1960s; these areas have undergone geographic changes in recent decades, apparently as a consequence of land-use changes in Andalusia. The percentages of the variables that were positively associated with rabbit favourability in both models (current and 1960s) have declined in Andalusia as a whole, and in areas where rabbit favourability has decreased; hence environments suitable for rabbits have become impoverished. Conversely, in both models, environments suitable for rabbits increased in municipalities, where rabbit favourability also increased. The preservation of rabbit-friendly habitats should be a priority for the conservation of this key species in the western Mediterranean.M. Delibes-Mateos was supported by a postdoctoral grant 469 from the regional government of Castilla la Mancha (JCCM) 470 and the European Social Fund (ESF).Peer Reviewe

    Oportunidades de colaboración entre farmacia hospitalaria y comunitaria

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    Divergent evolution and purifying selection of the flaA gene sequences in Aeromonas

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    <p>Abstract</p> <p>Background</p> <p>The bacterial flagellum is the most important organelle of motility in bacteria and plays a key role in many bacterial lifestyles, including virulence. The flagellum also provides a paradigm of how hierarchical gene regulation, intricate protein-protein interactions and controlled protein secretion can result in the assembly of a complex multi-protein structure tightly orchestrated in time and space. As if to stress its importance, plants and animals produce receptors specifically dedicated to the recognition of flagella. Aside from motility, the flagellum also moonlights as an adhesion and has been adapted by humans as a tool for peptide display. Flagellar sequence variation constitutes a marker with widespread potential uses for studies of population genetics and phylogeny of bacterial species.</p> <p>Results</p> <p>We sequenced the complete flagellin gene <it>(flaA</it>) in 18 different species and subspecies of <it>Aeromonas</it>. Sequences ranged in size from 870 (<it>A. allosaccharophila</it>) to 921 nucleotides (<it>A. popoffii</it>). The multiple alignment displayed 924 sites, 66 of which presented alignment gaps. The phylogenetic tree revealed the existence of two groups of species exhibiting different FlaA flagellins (FlaA1 and FlaA2). Maximum likelihood models of codon substitution were used to analyze <it>flaA </it>sequences. Likelihood ratio tests suggested a low variation in selective pressure among lineages, with an ω ratio of less than 1 indicating the presence of purifying selection in almost all cases. Only one site under potential diversifying selection was identified (isoleucine in position 179). However, 17 amino acid positions were inferred as sites that are likely to be under positive selection using the branch-site model. Ancestral reconstruction revealed that these 17 amino acids were among the amino acid changes detected in the ancestral sequence.</p> <p>Conclusion</p> <p>The models applied to our set of sequences allowed us to determine the possible evolutionary pathway followed by the <it>flaA </it>gene in <it>Aeromonas</it>, suggesting that this gene have probably been evolving independently in the two groups of <it>Aeromonas </it>species since the divergence of a distant common ancestor after one or several episodes of positive selection.</p> <p>Reviewers</p> <p>This article was reviewed by Alexey Kondrashov, John Logsdon and Olivier Tenaillon (nominated by Laurence D Hurst).</p

    Oportunidades de colaboración entre farmacia hospitalaria y comunitaria

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