Understanding the Impact of Meteorological Spatiotemporal Variability on Distant Focusing Overpressure Risk

Since the 1950s, the amplification of blast energy from explosions has been understood to be a significant hazard to public safety at launch ranges. Historically, the risk assessment of the Distant Focusing Overpressure (DFO) hazard started with a single temperature and wind profile (e.g., a radiosonde launch) as input to acoustic 1-D ray tracing models. By analyzing rays propagation and performing ray tracing, population centers under high DFO risk can be identified. Although this method is useful, less is known about how the blast waves can be focused when the spatiotemporal variability of the input profiles are considered. In summary, this work aims to consider how realistic atmospheric boundary layer variability (e.g., turbulence, land-surface contrasts) may affect blast waves propagation and focusing and, as a result, DFO risk assessment results

Issued as a Documentation Report on an Investigation of Field-Made Joints in Prestressed Reinforced Concrete Highway Girder Bridges, Project IHR-303, Phase 2

A prototype bridge girder was designed, built, and tested. The 250 ft long two-span girder was made of 3 precast segments about 88, 74, and 88 ft in length. The segments were supported on 3 final and 2 temporary supports. The joints were of cast-in-place concrete, as was the composite deck. After the site-cast concrete was cured, the structure was post-tensioned to establish continuity and the temporary supports were removed. The two longer segments were pretensioned to resist the girder and deck dead loads, while the shorter segment was reinforced with deformed bars for the same loads. The structure was subjected to a series of loadings, during which deflections, reactions, and concrete strains were measured. The loads approximated AASHTO HS-20 vehicles. The first 4 tests ,were to service loads, with total applied loads of 73.6 kips. The structure remained elastic and crack free during these tests. Two tests were to the design ultimate load, 198.7 kips. A load of 328.2 kips was applied in the final test without causing failure. The final loading was applied to produce maximum shear in one splice, and a shear failure, complicated by large flexural deformations, appeared to be developing when the test ended. The final test produced a maximum deflection of 10.8 in., and a residual of about 1.0 in. The joint details used in the prototype structure were adequate, and the presence of the, joint had no influence on the behavior of the structure until extremely large overloads were reached.State of Illinois Department of TransportationU.S. Department of Transportation. Federal Highway AdministrationProject IHR-30

Discriminant analysis for the prediction and classification of tick-borne infections in some dairy cattle herds at Dakahlia Governorate, Egypt

This study was undertaken to use the variable loadings in linear discriminant analysis (LDA) to determine the most important predictors for the discrimination of tick-borne diseases (TBDs), particularly babesiosis and anaplasmosis and predict the group membership from the predictors. In total, 163 cattle, from different localities at Dakahlia Governorate, Egypt, were investigated in 2012 and 2013 for the presence of TBDs. All cattle were clinically examined and a clinical index score was determined for each cow. Blood samples were also collected from each animal for adopting microscopy and diagnostic laboratory methods. Out of the examined cattle, 83 animals were acutely-ill (Babesia bovis and Anaplasma marginale were identified in 11 and 10 animals, respectively), while 80 cows were apparently healthy but having previous attacks of blood parasites (23 animals harbored anaplasma marginale (asymptomatic carriers)). The remained 119 animals were negative to TBDs. Fourteen animals were not survived and 149 cases were survived. As the result of the first LDA to discriminate babesiosis, anaplasmosis and negative to TBDs, 89.0% of animals were correctly classified; 78.8% (26/33) for anaplasma, 100% (11/11) for babesia infections, 90.8% (108/119) for negative to TBDs, respectively. The important predictors for the discrimination were oculonasal discharge, bloody feces, hemoglobinuria, bloody feces and respiratory rate. On the other hand, the second LDA discrimination showed high classification accuracy of 87.1% for the discrimination of survivors and non-survivors; 89.9% (134/149) for survivors and 57.1% (8/14) for non-survivors, while the important predictors included oculonasal discharge, recumbent posture and nervous sign

Material growth and characterization for solid state devices

Manganese was used as the dopant for p-type InGaAs layers grown on semi-insulating (Fe-doped) and n-type (Sn-doped) InP substrates. Optical, electrical (Hall) and SIMS measurements were used to characterize the layers. Mn-diffusion into the substrate (during the growth of In GaAs) was observed only when Fe-doped substrates were used. Quaternary layers of two compositions corresponding to wavelengths (energy gaps) of approximated 1.52 micrometers were successfully grown at a constant temperature of 640 C and InP was grown in the temperature range of 640 C to 655 C. A study of the effect of pulses on the growth velocity of InP indicated no significant change as long as the average applied current was kept constant. A system for depositing films of Al2O3 by the pyrolysis of aluminum isopropoxide was designed and built. Deposited layers on Si were characterized with an ellipsometer and exhibited indices of refraction between 1.582 and 1.622 for films on the order of 3000 A thick. Undoped and p-type (Mn-doped) InGaAs epitaxial layers were also grown on Fe-doped InP substrates through windows in sputtered SiO2 (3200 A thick) layers

Cytokines as a predictor of progression to valvular disease in children with rheumatic fever

The immunologic basis of rheumatic fever is well established. However the role of penicillin in the control of the rheumatic process and the prevention of development of rheumatic heart disease is poorly understood.Objectivethe objective of this study was to monitor the changes in serum levels of Tumour Necrosis Factor (TNF-alpha) and interleukin-8 (IL-8) in children presenting with various stages of rheumatic fever over a time.Subjects and methodsStudy included 42 children aged 6–15 years with RHD followed up over one year by Doppler-echocardiography and laboratory tests to monitor IL-8 and TNF-alpha by ELISA technique.ResultsTwenty five children presented with acute arthritis with or without carditis (59.5%), all had statistically significantly high levels of IL-8 and TNF-alpha throughout the follow-up period. Of these 9 (36%) developed rheumatic reactivity and 6 (24%) developed valvular heart disease. Eight children (19%) presented with rheumatic chorea, all had significantly high levels of IL-8 and TNF-alpha throughout the follow-up period, of whom 4 (50%) developed valvular disease. Nine children (21.4%) presented with varying degrees of established chronic rheumatic heart disease, all of whom had no rise in the serum levels of IL-8 and TNF-alpha.ConclusionsThese findings indicate that the clinical and epidemiological pattern of rheumatic fever is changing. Immunemodulatory responses could assist us in tracking these changing patterns of disease and assessing current protocols of management

Material growth and characterization directed toward improving III-V heterojunction solar cells

In addition to the existing materials growth laboratory, the photolithographic facility and the device testing facility were completed. The majority of equipment for data acquisition, solar cell testing, materials growth and device characterization were received and are being put into operation. In the research part of the program, GaAs and GaA1As layers were grown reproducibly on GaAs substrates. These grown layers were characterized as to surface morphology, thickness and thickness uniformity. The liquid phase epitaxial growth process was used to fabricate p-n junctions in Ga(1-x)A1(x)As. Sequential deposition of two alloy layers was accomplished and detailed analysis of the effect of substrate quality and dopant on the GaA1As layer quality is presented. Finally, solar cell structures were formed by growing a thin p-GaA1As layer upon an epitaxial n-GaA1As layer. The energy gap corresponding to the long wavelength cutoff of the spectral response characteristic was 1.51-1.63 eV. Theoretical calculations of the spectral response were matched to the measured response