Towards a Semantic Gas Source Localization under Uncertainty

Towards a Semantic Gas Source Localization under Uncertainty.Communications in Computer and Information Science book series (CCIS, volume 855), doi:10.1007/978-3-319-91479-4_42This work addresses the problem of efficiently and coherently locating a gas source in a domestic environment with a mobile robot, meaning efficiently the coverage of the shortest distance as possible and coherently the consideration of different gas sources explaining the gas presence. The main contribution is the exploitation, for the first time, of semantic relationships between the gases detected and the objects present in the environment to face this challenging issue. Our proposal also takes into account both the uncertainty inherent in the gas classification and object recognition processes. These uncertainties are combined through a probabilistic Bayesian framework to provide a priority-ordered list of (previously observed) objects to check. Moreover the proximity of the different candidates to the current robot location is also considered by a cost function, which output is used for planning the robot inspection path. We have conducted an initial demonstration of the suitability of our gas source localization approach by simulating this task within domestic environments for a variable number of objects, and comparing it with an greedy approach.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Users' perceptions of domestic windows in Hong Kong: Challenging daylighting-based design regulations

The authors suspected that the contemporary quantified daylight control on window design is insufficient to satisfy the user expectation in Hong Kong. A survey was carried out from December 2007 to June 2008 to study the human-window interactions in high-rise residential buildings in Hong Kong. The result indicated that daylighting is not the dominant factor for domestic window design because of Hong Kong's sociocultural context; other factors such as dining habit, toilet hygiene, views from living room and privacy for bedroom proved to be more important in the users perception. This suggested that the current statutory control may not fulfill or match user expectations. Thus, the window design framework should be a qualitative approach with the understanding of space function and user behavior in the sociocultural context in order to provide for a better living environment. © 2010 Macmillan Publishers Ltd.postprin

Managerial incentives, CEO characteristics and corporate innovation in China's private sector

We use a unique World Bank survey of 1088 private manufacturing firms from 18 Chinese cities over the period 2000-2002 to empirically examine the roles of managerial incentives and CEO characteristics in a firm's innovation activities. We look at both innovation effort (R&D intensity) and innovation performance measures such as new product sales. We obtain the following main results: (1) the presence of CEO incentive schemes increases both corporate innovation effort and innovation performance; (2) sales-based performance measures in the incentive scheme, as compared with profit-based performance measure, are more conducive to firm innovation; and (3) CEO education level, professional background and political connection are positively associated with firm's innovation efforts. The main results are robust to endogeneity tests with instrumental variables. We also discuss some important policy implications. © 2010 Association for Comparative Economic Studies.postprin

D'yakonov-Perel' spin relaxation in InSb/AlInSb quantum wells

We investigate theoretically the D'yakonov-Perel' spin relaxation time by solving the eight-band Kane model and Poisson equation self-consistently. Our results show distinct behavior with the single-band model due to the anomalous spin-orbit interactions in narrow band-gap semiconductors, and agree well with the experiment values reported in recent experiment (K. L. Litvinenko, et al., New J. Phys. \textbf{8}, 49 (2006)). We find a strong resonant enhancement of the spin relaxation time appears for spin align along [$1\bar{1}0$] at a certain electron density at 4 K. This resonant peak is smeared out with increasing the temperature.Comment: 4 pages, 4 figure

TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness.

BACKGROUND: MiR-17-92 cluster and its paralogues have emerged as crucial regulators of many oncogenes and tumor suppressors. Transforming growth factor-β receptor II (TGFβR2), as an important tumor suppressor, is involved in various cancer types. However, it is in cancer that only two miRNAs of this cluster and its paralogues have been reported so far to regulate TGFβR2. MiR-93 is oncogenic, but its targetome in cancer has not been fully defined. The role of miR-93 in nasopharyngeal carcinoma (NPC) still remains largely unknown. METHODS: We firstly evaluated the clinical signature of TGFβR2 down-regulation in clinical samples, and next used a miRNA expression profiling analysis followed by multi-validations, including Luciferase reporter assay, to identify miRNAs targeting TGFβR2 in NPC. In vitro and in vivo studies were performed to further investigate the effects of miRNA-mediated TGFβR2 down-regulation on NPC aggressiveness. Finally, mechanism studies were conducted to explore the associated pathway and genes influenced by this miRNA-mediated TGFβR2 down-regulation. RESULTS: TGFβR2 was down-regulated in more than 50% of NPC patients. It is an unfavorable prognosis factor contributing to clinical NPC aggressiveness. A cluster set of 4 TGFβR2-associated miRNAs was identified; they are all from miR-17-92 cluster and its paralogues, of which miR-93 was one of the most significant miRNAs, directly targeting TGFβR2, promoting cell proliferation, invasion and metastasis in vitro and in vivo. Moreover, miR-93 resulted in the attenuation of Smad-dependent TGF-β signaling and the activation of PI3K/Akt pathway by suppressing TGFβR2, further promoting NPC cell uncontrolled growth, invasion, metastasis and EMT-like process. Impressively, the knockdown of TGFβR2 by siRNA displayed a consentaneous phenocopy with the effect of miR-93 in NPC cells, supporting TGFβR2 is a major target of miR-93. Our findings were also substantiated by investigation of the clinical signatures of miR-93 and TGFβR2 in NPC. CONCLUSION: The present study reports an involvement of miR-93-mediated TGFβR2 down-regulation in NPC aggressiveness, thus giving extended insights into molecular mechanisms underlying cancer aggressiveness. Approaches aimed at blocking miR-93 may serve as a promising therapeutic strategy for treating NPC patients

Casimir forces on a silicon micromechanical chip

Quantum fluctuations give rise to van der Waals and Casimir forces that dominate the interaction between electrically neutral objects at sub-micron separations. Under the trend of miniaturization, such quantum electrodynamical effects are expected to play an important role in micro- and nano-mechanical devices. Nevertheless, utilization of Casimir forces on the chip level remains a major challenge because all experiments so far require an external object to be manually positioned close to the mechanical element. Here, by integrating a force-sensing micromechanical beam and an electrostatic actuator on a single chip, we demonstrate the Casimir effect between two micromachined silicon components on the same substrate. A high degree of parallelism between the two near-planar interacting surfaces can be achieved because they are defined in a single lithographic step. Apart from providing a compact platform for Casimir force measurements, this scheme also opens the possibility of tailoring the Casimir force using lithographically defined components of non-conventional shapes

Clinical-pathological study on β-APP, IL-1β, GFAP, NFL, Spectrin II, 8OHdG, TUNEL, miR-21, miR-16, miR-92 expressions to verify DAI-diagnosis, grade and prognosis

Traumatic brain injury (TBI) is one of the most important death and disability cause, involving substantial costs, also in economic terms, when considering the young age of the involved subject. Aim of this paper is to report a series of patients treated at our institutions, to verify neurological results at six months or survival; in fatal cases we searched for βAPP, GFAP, IL-1β, NFL, Spectrin II, TUNEL and miR-21, miR-16, and miR-92 expressions in brain samples, to verify DAI diagnosis and grade as strong predictor of survival and inflammatory response. Concentrations of 8OHdG as measurement of oxidative stress was performed. Immunoreaction of β-APP, IL-1β, GFAP, NFL, Spectrin II and 8OHdG were significantly increased in the TBI group with respect to control group subjects. Cell apoptosis, measured by TUNEL assay, were significantly higher in the study group than control cases. Results indicated that miR-21, miR-92 and miR-16 have a high predictive power in discriminating trauma brain cases from controls and could represent promising biomarkers as strong predictor of survival, and for the diagnosis of postmortem traumatic brain injury

Reversible Data Perturbation Techniques for Multi-level Privacy-preserving Data Publication

The amount of digital data generated in the Big Data age is increasingly rapidly. Privacy-preserving data publishing techniques based on differential privacy through data perturbation provide a safe release of datasets such that sensitive information present in the dataset cannot be inferred from the published data. Existing privacy-preserving data publishing solutions have focused on publishing a single snapshot of the data with the assumption that all users of the data share the same level of privilege and access the data with a fixed privacy level. Thus, such schemes do not directly support data release in cases when data users have different levels of access on the published data. While a straight-forward approach of releasing a separate snapshot of the data for each possible data access level can allow multi-level access, it can result in a higher storage cost requiring separate storage space for each instance of the published data. In this paper, we develop a set of reversible data perturbation techniques for large bipartite association graphs that use perturbation keys to control the sequential generation of multiple snapshots of the data to offer multi-level access based on privacy levels. The proposed schemes enable multi-level data privacy, allowing selective de-perturbation of the published data when suitable access credentials are provided. We evaluate the techniques through extensive experiments on a large real-world association graph dataset and our experiments show that the proposed techniques are efficient, scalable and effectively support multi-level data privacy on the published data

Phonon-assisted radiofrequency absorption by gold nanoparticles resulting in hyperthermia

It is suggested that in gold nanoparticles (GNPs) of about 5 nm sizes used in the radiofrequency (RF) hyperthermia, an absorption of the RF photon by the Fermi electron occurs with involvement of the longitudinal acoustic vibrational mode (LAVM), the dominating one in the distribution of vibrational density of states (VDOS). This physical mechanism helps to explain two observed phenomena: the size dependence of the heating rate (HR) in GNPs and reduced heat production in aggregated GNPs. The argumentation proceeds within the one-electron approximation, taking into account the discretenesses of energies and momenta of both electrons and LAVMs. The heating of GNPs is thought to consist of two consecutive processes: first, the Fermi electron absorbs simultaneously the RF photon and the LAVM available in the GNP; hereafter the excited electron gets relaxed within the GNP's boundary, exciting a LAVM with the energy higher than that of the previously absorbed LAVM. GNPs containing the Ta and/or Fe impurities are proposed for the RF hyperthermia as promising heaters with enhanced HRs, and GNPs with rare-earth impurity atoms are also brought into consideration. It is shown why the maximum HR values should be expected in GNPs with about 5-7 nm size.Comment: proceedings at the NATO Advanced Research workshop FANEM-2015 (Minsk, May 25-27, 2015). To be published in the final form in: "Fundamental and Applied NanoElectroMagnetics" (Springer Science + Business Media B.V.