5,318 research outputs found
Dimeticone 4% liquid gel found to kill all lice and eggs with a single 15 minute application
<p>Abstract</p> <p>Background</p> <p>Dimeticone 4% lotion is an effective and widely accepted treatment for head louse infestation. However, it is a highly mobile fluid that some people find difficult to apply and is mainly left on the hair for 8 hours or overnight. User preference is for a more manageable and viscous product that can be used with a short application time.</p> <p>Findings</p> <p>This proof of concept study in 41 people investigated dimeticone 4% liquid gel, a product that is easier to apply than the lotion, applied for 15 minutes on two occasions a week apart. We found that head lice were eliminated from all participants following the first application of product. We did not find lice of any stage on any participant during four post treatment assessments and particularly, unlike other treatments, no young nymphs on days 1 and 6 prior to the second treatment, indicating ovicidal as well as pediculicidal activity.</p> <p>Conclusions</p> <p>Dimeticone 4% liquid gel has demonstrated efficacy greater than other similar products and the evidence obtained indicates elimination of head louse infestation with a single 15 minute application.</p> <p>Trial registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN59227204">ISRCTN59227204</a></p
Sources of Relativistic Jets in the Galaxy
Black holes of stellar mass and neutron stars in binary systems are first
detected as hard X-ray sources using high-energy space telescopes. Relativistic
jets in some of these compact sources are found by means of multiwavelength
observations with ground-based telescopes. The X-ray emission probes the inner
accretion disk and immediate surroundings of the compact object, whereas the
synchrotron emission from the jets is observed in the radio and infrared bands,
and in the future could be detected at even shorter wavelengths. Black-hole
X-ray binaries with relativistic jets mimic, on a much smaller scale, many of
the phenomena seen in quasars and are thus called microquasars. Because of
their proximity, their study opens the way for a better understanding of the
relativistic jets seen elsewhere in the Universe. From the observation of
two-sided moving jets it is inferred that the ejecta in microquasars move with
relativistic speeds similar to those believed to be present in quasars. The
simultaneous multiwavelength approach to microquasars reveals in short
timescales the close connection between instabilities in the accretion disk
seen in the X-rays, and the ejection of relativistic clouds of plasma observed
as synchrotron emission at longer wavelengths. Besides contributing to a deeper
comprehension of accretion disks and jets, microquasars may serve in the future
to determine the distances of jet sources using constraints from special
relativity, and the spin of black holes using general relativity.Comment: 39 pages, Tex, 8 figures, to appear in vol. 37 (1999) of Annual
Reviews of Astronomy and Astrophysic
Performance analysis of cables with attached tuned-inerter-dampers
Cables are structural elements designed to bear tensile forces and experience vibration problems due to their slenderness and low mass. In the field of civil engineering, they are mostly used in bridges where the vibrations are mainly induced by wind, rain, traffic and earthquakes. This paper proposes the use of a tuned-inerter-damper (TID) system, mounted on cables to suppress unwanted vibrations. These are to be attached transversally to the cable, in the vicinity of the support, connected between the deck and the cable. The potential advantage of using a TID system consists in the high apparent mass that can be produced by the inerter. Our analysis showed that the modal damping ratio obtained is much higher than in the case of traditional dampers or tuned mass dampers, leading to an improved overall response. An optimal tuning methodology is also discussed. Numerical results are shown with a cable subjected to both free and forced vibrations and the TID performance is improved when compared with equivalent dampers
On the role of magnetic reconnection in jet/accretion disk systems
The most accepted model for jet production is based on the
magneto-centrifugal acceleration out off an accretion disk that surrounds the
central source (Blandford & Payne, 1982). This scenario, however, does not
explain, e.g., the quasi-periodic ejection phenomena often observed in
different astrophysical jet classes. de Gouveia Dal Pino & Lazarian (2005)
(hereafter GDPL) have proposed that the large scale superluminal ejections
observed in microquasars during radio flare events could be produced by violent
magnetic reconnection (MR) episodes. Here, we extend this model to other
accretion disk systems, namely: active galactic nuclei (AGNs) and young stellar
objects (YSOs), and also discuss its role on jet heating and particle
acceleration.Comment: To be published in the IAU Highlights of Astronomy, Volume 15, XXVII
IAU General Assembly, August 2009, Ian F. Corbett et al., eds., 201
Triple Higgs coupling in the most general 2HDM at SM-like scenario
We consider the triple Higgs coupling for h(125) Higgs boson within the most general 2HDM. At moderate values of parameters of model, allowing by modern data, noticeable deviation of this coupling from its SM value is improbable. This deviation can be sizable only if some measurable parameters of the model are exotic
Impact of patent ductus arteriosus on non-invasive assessments of lung fluids in very preterm infants during the transitional period
This prospective observational study aimed to evaluate whether lung fluids, assessed by lung ultrasonography and transthoracic electrical bioimpedance (TEB), may be influenced by the presence of a haemodynamically significant patent ductus arteriosus (hsPDA) in very preterm infants during the transitional period. Infants < 32 weeks of gestational age (GA) admitted to the neonatal intensive care units of IRCCS AOU Bologna and Niguarda Metropolitan Hospital of Milan (Italy) underwent a daily assessment of a lung ultrasound score (LUS) and of a TEB-derived index of thoracic fluid contents (TFC) during the first 72 h after birth. Echocardiographic scans were simultaneously performed to evaluate the concomitant ductal status (hsPDA vs. restrictive or closed duct). The correlation between LUS, TFC, and the ductal status was tested using generalized estimating equations. Forty-six infants (median GA: 29 [interquartile range, IQR: 27-31] weeks; median birth weight: 1099 [IQR: 880-1406] g) were included. At each daily evaluation, the presence of a hsPDA was associated with significantly higher LUS and TFC compared with a restrictive or closed ductus (p < 0.01 for all comparisons). These results were confirmed significant even after adjustment for GA and for the ongoing modality of respiratory support.Conclusion: Even during the first 72 h of life, the presence of a hsPDA determines a significant increase in pulmonary fluids which can be non-invasively detected and monitored over time using lung ultrasonography and TEB
A new two-phase dimeticone pediculicide shows high efficacy in a comparative bioassay
Background: \ud
Dimeticones kill head lice by physical means. Here we assessed in a comparative bioassay the ex vivo efficacy of "NYDA® sensitiv", a new two-phase dimeticone-based pediculicide similar to a product established on the market, but without fragrances.\ud
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Methods:\ud
We compared efficacy of the new product to a positive dimeticone control group, a sample of four other insecticidal and natural head lice products marketed in Germany, and an untreated control. In a bioassay, lice were exposed ex vivo to products and examined for activity for up to 24 hours, following a standard protocol.\ud
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Results:\ud
After 6 and 24 hours, 13.7 and 88.5% of untreated control lice did not show major vital signs. In contrast, no lice showed major vital signs 5 minutes after treatment with the new product or the control dimeticone group (NYDA®). This effect persisted at all observation points (100% efficacy). Efficacy of 0.5% permethrin (Infectopedicul®) ranged between 76 and 96% in evaluations between 5 min and 6 hours. All lice treated with a coconut-based compound (mosquito® Läuseshampoo) did not show major vital signs after 5 min, but mortality was only 58% after one hour. Pyrethrum extract (Goldgeist® forte) showed an efficacy of 22 - 52% between 5 min and 3 hours after treatment; after 6 hours, 76% of lice were judged dead. An oxyphthirine®-based compound (Liberalice DUO LP-PRO®) killed 22 - 54% of lice in the first 6 hours.\ud
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Conclusions:\ud
The two-phase dimeticone compound NYDA® sensitiv is highly efficacious. The removal of fragrances as compared to an established dimeticone product did not affect in vitro efficacy
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