Proper Motion of Pulsar B1800-21

We report high angular resolution, multi-epoch radio observations of the young pulsar PSR B1800-21. Using two pairs of data sets, each pair spanning approximately a ten year period, we calculate the proper motion of the pulsar. We obtain a proper motion of mu_alpha=11.6 +- 1.8 mas/yr, mu_delta=14.8 +- 2.3 mas/yr, which clearly indicates a birth position at the extreme edge of the W30 supernova remnant. Although this does not definitively rule out an association of W30 and PSR B1800-21, it does not support an association.Comment: 13 pages, 1 color figure. Replaced with version accepted for publication in Astrophysical Journa

Habitability: CAMELOT 4

During 1988 to 1989 the NASA/USRA Advanced Design Program sponsored research and design efforts aimed at developing habitability criteria and at defining a habitability concept as a useful tool in understanding and evaluating dwellings for prolonged stays in extraterrestrial space. The Circulating Auto sufficient Mars-Earth Luxurious Orbital Transport (CAMELOT) was studied as a case in which the students would try to enhance the quality of life of the inhabitants by applying architectural design methodology. The study proposed 14 habitability criteria considered necessary to fulfill the defined habitability concept, which is that state of equilibrium that results from the interaction between components of the Individual Architecture Mission Complex, which allows a person to sustain physiological homeostatis, adequate performance, and acceptable social relationships. Architecture, design development, refinements and revisions to improve the quality of life, new insights on artificial gravity, form and constitution problems, and the final design concept are covered

Efficient generation of data sets for one-shot statistical calibration of RF/mm-wave circuits

International audienc

The Effects of Two Different Resisted Swim Training Load Protocols on Swimming Strength and Performance

This study used a power rack device to evaluate the effects of 2 different approaches to resisted swim training loads on swimming strength and performance. Sixteen male, youth national-level swimmers (mean age, 16.22 +/- 2.63 years; body height, 169 +/- 10.20 cm; body mass, 61.33 +/- 9.90 kg) completed a 6-week specific strength-training program, and were then randomly assigned to one of the two groups: a standard training group (GS, n = 8) and a flat pyramid-loading pattern group (GP, n = 8). Strength and power tests along with specific swimming tests (50-m crawl and 50-m competition-style time trials) were conducted at baseline (pre-test), before the third week (mid-test), and after 6 weeks of intervention (post-test). Isokinetic swim bench tests were conducted to obtain measurements of force production and power, and 1RM tests with the power rack system were conducted to measure the maximum drag load (MDL) and specific swimming power. Following 6 weeks of intervention, the mean MDL increased (p < 0.05) by 13.94%. Scores for the 50-m competition style and 50-m crawl time trials improved by 0.32% and 0.78%, respectively, in the GP; however, those changes were not statistically significant. The GS significantly increased their time in the 50-m competition style by 2.59%, and their isokinetic force production decreased by 14.47% (p < 0.05). The 6-week strength-training program performed with the power rack device in a pyramidal organization was more effective than a standard linear load organization in terms of producing improvements in the MDL; however, it did not produce significant improvements in performance. The use of a strength-training program with a pyramidal organization can be recommended for specific strength-training in young swimmers during a preparatory period. However, in our study, that program did not produce significant changes in 50-m crawl and main competition style performance

Psychedelics Promote Structural and Functional Neural Plasticity.

Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both&nbsp;structural and functional plasticity in the PFC has been hypothesized to underlie the fast-acting antidepressant properties of the dissociative anesthetic ketamine. Here, we report that, like ketamine, serotonergic psychedelics are capable of robustly increasing neuritogenesis and/or spinogenesis both in&nbsp;vitro and in&nbsp;vivo. These changes in neuronal structure are accompanied by increased synapse number and function, as measured by fluorescence microscopy and electrophysiology. The structural changes induced by psychedelics appear to result from stimulation of the TrkB, mTOR, and 5-HT2A signaling pathways and could possibly explain the clinical effectiveness of these compounds. Our results underscore the therapeutic potential of psychedelics and, importantly, identify several lead scaffolds for medicinal chemistry efforts focused on developing plasticity-promoting compounds as safe, effective, and fast-acting treatments for depression and related disorders

Study of the many fluorescent lines and the absorption variability in GX 301-2 with XMM-Newton

We present an in-depth study of the High Mass X-ray Binary (HMXB) GX 301-2 during its pre-periastron flare using data from the XMM-Newton satellite. The energy spectrum shows a power law continuum absorbed by a large equivalent hydrogen column on the order of 10^24 cm^2 and a prominent Fe K-alpha fluorescent emission line. Besides the Fe K-alpha line, evidence for Fe K-beta, Ni K-alpha, Ni K-beta, S K-alpha, Ar K-alpha, Ca K-alpha, and Cr K-alpha fluorescent lines is found. The observed line strengths are consistent with fluorescence in a cold absorber. This is the first time that a Cr K-alpha line is seen in emission in the X-ray spectrum of a HMXB. In addition to the modulation by the strong pulse period of ~685 sec the source is highly variable and shows different states of activity. We perform time-resolved as well as pulse-to-pulse resolved spectroscopy to investigate differences between these states of activity. We find that the fluorescent line fluxes are strongly variable and generally follow the overall flux. The N_H value is variable by a factor of 2, but not correlated to the continuum normalization. We find an interval of low flux in the light curve in which the pulsations cease almost completely, without any indication of an increasing absorption column. We investigate this dip in detail and argue that it is most likely that during the dip the accretion ceased and the afterglow of the fluorescent iron accounted for the main portion of the X-ray flux. A similar dip was found earlier in RXTE data, and we compare our findings to these resultsComment: 13 pages, 13 Figures, published in A&

CR1 Knops blood group alleles are not associated with severe malaria in the Gambia

The Knops blood group antigen erythrocyte polymorphisms have been associated with reduced falciparum malaria-based in vitro rosette formation (putative malaria virulence factor). Having previously identified single-nucleotide polymorphisms (SNPs) in the human complement receptor 1 (CR1/CD35) gene underlying the Knops antithetical antigens Sl1/Sl2 and McC(a)/McC(b), we have now performed genotype comparisons to test associations between these two molecular variants and severe malaria in West African children living in the Gambia. While SNPs associated with Sl:2 and McC(b+) were equally distributed among malaria-infected children with severe malaria and control children not infected with malaria parasites, high allele frequencies for Sl 2 (0.800, 1,365/1,706) and McC(b) (0.385, 658/1706) were observed. Further, when compared to the Sl 1/McC(a) allele observed in all populations, the African Sl 2/McC(b) allele appears to have evolved as a result of positive selection (modified Nei-Gojobori test Ka-Ks/s.e.=1.77, P-value &lt;0.05). Given the role of CR1 in host defense, our findings suggest that Sl 2 and McC(b) have arisen to confer a selective advantage against infectious disease that, in view of these case-control study data, was not solely Plasmodium falciparum malaria. Factors underlying the lack of association between Sl 2 and McC(b) with severe malaria may involve variation in CR1 expression levels

Morphology of radio relics-II. Properties of polarized emission

Radio relics are diffuse radio sources in galaxy clusters that are associated with merger shock waves. Detailed observations of radio relics in total intensity and in polarization show complex structures on kiloparsec scales. The relation between the observed features and the underlying morphology of the magnetic field is not clear. Using 3D magneto-hydrodynamical simulations, we study the polarized emission produced by a shock wave that propagates through a turbulent medium that resembles the intracluster medium. We model the polarized synchrotron emission on the basis of diffusive shock acceleration of cosmic ray electrons. We find that the synchrotron emission produced in a shocked turbulent medium can reproduce some of the observed features in radio relics. Shock compression can give rise to a high polarization fraction at the shock front and a partial alignment of the polarization E-vectors with the shock normal. Our work confirms that radio relics can also be formed in an environment with a tangled magnetic field. We also discuss the effect of Faraday rotation intrinsic to the source, and how our results depend on the angular resolution of observations

Exploring Scenedesmus obliquus and nannochloropsis sp. potential as a sustianable raw material for biofuels amd high added value compounds

In this work, the authors propose a microalga-based integrated system, where optimization of several energy vectors (biodiesel, bioethanol and bioH2) is highlighted under the concept of biorefinery (Project PTDC/AAC-AMB/100354/2008). This involves the integration of different processes such as oil and sugar extraction from microalgae for biodiesel and bioethanol production respectively, and bioH2 production from the whole and/or biomass leftovers. The extraction of high value added compounds, such as carotenoids, contributes to the economic viability of the overall process