Echocardiographic estimation of mean pulmonary artery pressure in critically ill patients

BACKGROUND: Indirect assessment of mean pulmonary arterial pressure (MPAP) may assist management of critically ill patients with pulmonary hypertension and right heart dysfunction. MPAP can be estimated as the sum of echocardiographically derived mean right ventricular to right atrial systolic pressure gradient and right atrial pressure; however, this has not been validated in critically ill patients. METHODS: This prospective validation study was conducted in patients undergoing pulmonary artery catheterisation during intensive care admission. Pulmonary artery catheter (PAC) measurements of MPAP were contemporaneously compared to MPAP estimated utilising transthoracic echocardiography (TTE)-derived mean right ventricular to right atrial systolic pressure gradient added to invasively measured right atrial pressure. RESULTS: Of 53 patients assessed, 23 had estimable MPAP using TTE. The mean difference between TTE- and PAC-derived MPAP was 1.9 mmHg (SD 5.0), with upper and lower limits of agreement of 11.6 and −7.9 mmHg, respectively. The median absolute percentage difference between TTE- and PAC-derived MPAP was 7.5%. Inter-rater reliability assessment was performed for 15 patients, giving an intra-class correlation coefficient of 0.96 (95% confidence intervals, 0.89 to 0.99). CONCLUSIONS: This echocardiographic method of estimating MPAP in critically ill patients was not equivalent to invasively measured MPAP, based on our predefined clinically acceptable range (±5 mmHg). The accuracy of this method in critically ill patients was similar to the results obtained in ambulatory patients and compared favourably with regard to the accuracy with echocardiographic estimation of systolic pulmonary arterial pressure. The utility of this technique is limited by frequent inability to obtain an adequate tricuspid regurgitant time-velocity integral in critically ill patients

Classification of dynamical Lie algebras for translation-invariant 2-local spin systems in one dimension

Much is understood about 1-dimensional spin chains in terms of entanglement properties, physical phases, and integrability. However, the Lie algebraic properties of the Hamiltonians describing these systems remain largely unexplored. In this work, we provide a classification of all Lie algebras generated by translation-invariant 2-local spin chain Hamiltonians, or so-called dynamical Lie algebras. We consider chains with open and periodic boundary conditions and find 17 unique dynamical Lie algebras. Our classification covers some well-known models such as the transverse-field Ising model and the Heisenberg chain, and we also find more exotic classes of Hamiltonians that cannot be identified easily. In addition to the closed and open spin chains, we consider systems with a fully connected topology, which may be relevant for quantum machine learning approaches. We discuss the practical implications of our work in the context of quantum control, variational quantum computing, and the spin chain literature

The origin of polarization in kilonovae and the case of the gravitational-wave counterpart AT 2017gfo

The gravitational-wave event GW 170817 was generated by the coalescence of two neutron stars and produced an electromagnetic transient, labelled AT 2017gfo, that was the target of a massive observational campaign. Polarimetry is a powerful diagnostic tool for probing the geometry and emission processes of unresolved sources, and the observed linear polarization for this event was consistent with being mostly induced by intervening dust, suggesting that the intrinsic emission was weakly polarized (P < 0.4–0.5%). Here we present a detailed analysis of the linear polarization expected from a merging neutron-star binary system by means of 3D Monte Carlo radiative transfer simulations assuming a range of possible configurations, wavelengths, epochs and viewing angles. We find that polarization originates from the non-homogeneous opacity distribution within the ejecta and can reach levels of 1% at early times (one to two days after the merger) and in the optical R band. Smaller polarization signals are expected at later epochs and different wavelengths. From the viewing-angle dependence of the polarimetric signal, we constrain the observer orientation of AT 2017gfo to within about 65° from the polar direction. The detection of non-zero polarization in future events will unambiguously reveal the presence of a lanthanide-free ejecta component and unveil its spatial and angular distribution

The January 2015 outburst of a red nova in M31

M31N 2015-01a (or M31LRN 2015) is a red nova that erupted in January 2015 -- the first event of this kind observed in M31 since 1988. Very few similar events have been confirmed as of 2015. Most of them are considered to be products of stellar mergers. Results of an extensive optical monitoring of the transient in the period January-March 2015 are presented. Eight optical telescopes were used for imaging. Spectra were obtained on BTA, GTC and the Rozhen 2m telescope. We present a highly accurate 70 d lightcurve and astrometry with a 0.05" uncertainty. The color indices reached a minimum 2-3 d before peak brightness and rapidly increased afterwards. The spectral type changed from F5I to F0I in 6 d before the maximum and then to K3I in the next 30 d. The luminosity of the transient was estimated to $8.7^{+3.3}_{-2.2}\times10^{5}L_{\odot}$ during the optical maximum. Both the photometric and the spectroscopic results confirm that the object is a red nova, similar to V838 Monocerotis.Comment: 5 pages, 4 figures, 4 tables, accepted for publication in Astronomy and Astrophysics as a Letter to the Editor; page 5 is online material onl

SPLOT : a Snapshot survey for polarised light in optical transients

We present SPLOT, a small scale pilot survey to test the potential of snapshot (single epoch) linear imaging polarimetry as a supplementary tool to traditional transient follow-up. Transients exist in a vast volume of observational parameter space and polarimetry has the potential to highlight sources of scienti c interest and add value to near real-time transient survey streams. We observed a sample of 50 randomly selected optical transients with the EFOSC2 and SofI instruments, on the 3.6m New Technology Telescope (NTT) to test the feasibility of the survey. Our sample contained a number of interesting individual sources: a variety of supernovae, X-ray binaries, a tidal disruption event, blazar outbursts, and, by design, numerous transients of unknown nature. We discuss the results, both for the individual sources and the survey in detail. We provide an overview on the success and limitations of SPLOT and also describe a novel calibration method for removing instrumental polarisation e ects from Nasymth-mounted telescopes. We nd that a SPLOT-like survey would be a bene t to the large scale future transient survey streams such as LSST. The polarimetric measurements have added scienti c value to a signi cant number of the sources and, most importantly, has shown the potential to highlight unclassi ed transient sources of scienti c interest for further study

The warm, the excited, and the molecular gas: GRB 121024A shining through its star-forming galaxy

We present the first reported case of the simultaneous metallicity determination of a gamma-ray burst (GRB) host galaxy, from both afterglow absorption lines as well as strong emission-line diagnostics. Using spectroscopic and imaging observations of the afterglow and host of the long-duration Swift GRB121024A at z = 2.30, we give one of the most complete views of a GRB host/environment to date. We observe a strong damped Ly-alpha absorber (DLA) with a hydrogen column density of log N(HI) = 21.88 +/- 0.10, H2 absorption in the Lyman-Werner bands (molecular fraction of log(f)~ -1.4; fourth solid detection of molecular hydrogen in a GRB-DLA), the nebular emission lines H-alpha, H-beta, [O II], [O III] and [N II], as well as metal absorption lines. We find a GRB host galaxy that is highly star-forming (SFR ~ 40 solar masses/yr ), with a dust-corrected metallicity along the line of sight of [Zn/H]corr = -0.6 +/- 0.2 ([O/H] ~ -0.3 from emission lines), and a depletion factor [Zn/Fe] = 0.85 +/- 0.04. The molecular gas is separated by 400 km/s (and 1-3 kpc) from the gas that is photoexcited by the GRB. This implies a fairly massive host, in agreement with the derived stellar mass of log(M/M_solar ) = 9.9+/- 0.2. We dissect the host galaxy by characterising its molecular component, the excited gas, and the line-emitting star-forming regions. The extinction curve for the line of sight is found to be unusually flat (Rv ~15). We discuss the possibility of an anomalous grain size distributions. We furthermore discuss the different metallicity determinations from both absorption and emission lines, which gives consistent results for the line of sight to GRB 121024A.Comment: 20 pages, 11 figures, accepted by MNRA

Economic liberalization and the antecedents of top management teams: evidence from Turkish 'big' business

There has been an increased interest in the last two decades in top management teams (TMTs) of business firms. Much of the research, however, has been US-based and concerned primarily with TMT effects on organizational outcomes. The present study aims to expand this literature by examining the antecedents of top team composition in the context of macro-level economic change in a late-industrializing country. The post-1980 trade and market reforms in Turkey provided the empirical setting. Drawing upon the literatures on TMT and chief executive characteristics together with punctuated equilibrium models of change and institutional theory, the article develops the argument that which firm-level factors affect which attributes of TMT formations varies across the early and late stages of economic liberalization. Results of the empirical investigation of 71 of the largest industrial firms in Turkey broadly supported the hypotheses derived from this premise. In the early stages of economic liberalization the average age and average organizational tenure of TMTs were related to the export orientation of firms, whereas in later stages, firm performance became a major predictor of these team attributes. Educational background characteristics of teams appeared to be under stronger institutional pressures, altering in different ways in the face of macro-level change