Spatially resolved microwave pulsations of a flare loop

A microwave burst with quasi-periodic pulsations was studied with high spatial resolution using observations with the Nobeyama Radioheliograph (NoRH). We found that the time profiles of the microwave emission at 17 and 34 GHz exhibit quasi-periodic (with two well defined periods P 1 = 14–17 s and P 2 = 8–11 s) variations of the intensity at different parts of an observed flaring loop. Detailed Fourier analysis shows the P 1 spectral component to be dominant at the top, while the P 2 one near the feet of the loop. The 14–17 s pulsations are synchronous at the top and in both legs of the loop. The 8–11 s pulsations at the legs are well correlated with each other but the correlation is not so obvious with the pulsations at the loop top. For this P 2 spectral component, a definite phase shift, P 2 /4 ≈ 2.2 s, between pulsations in the northern leg and loop top parts of the loop have been found. The length of the flaring loop is estimated as L = 25 Mm (≈34 ) and its average width at half intensity at 34 GHz as about 6 Mm (≈8 ). Microwave diagnostics shows the loop to be filled with a dense plasma with the number density n 0 ≈ 10 11 cm −3, penetrated by the magnetic field changing from B 0 ≈ 100 G near the loop top up to B 0 ≈ 200 G near the north footpoint. A comparative analysis of different MHD modes of the loop demonstrates the possibility of the simultaneous existence of two modes of oscillations in the loop: the global sausage mode, with the period P 1 = 14–17 s and the nodes at the footpoints, and a higher harmonics mode (possibly with the radial wave number l > 1), with P 2 = 8–11 s

Effect of solar cycle 23 in foF2 trend estimation

The effect of including solar cycle 23 in foF2 trend estimation is assessed using experimental values for Slough (51.5°N, 359.4°E) and Kokobunji (35.7°N, 139.5°E), and values obtained from two models: (1) the Sheffield University Plasmasphere-Ionosphere model, SUPIM, and (2) the International Reference Ionosphere, IRI. The dominant influence on the F2 layer is solar extreme ultraviolet (EUV) radiation, evinced by the almost 90% variance of its parameters explained by solar EUV proxies such as the solar activity indices Rz and F10.7. This makes necessary to filter out solar activity effects prior to long-term trend estimation. Solar cycle 23 seems to have had an EUV emission different from that deduced from traditional solar EUV proxies. During maximum and descending phase of the cycle, Rz and F10.7 seem to underestimate EUV solar radiation, while during minimum, they overestimate EUV levels. Including this solar cycle in trend estimations then, and using traditional filtering techniques, may induce some spurious results. In the present work, filtering is done in the usual way considering the residuals of the linear regression between foF2 and F10.7, for both experimental and modeled values. foF2 trends become less negative as we include years after 2000, since foF2 systematically exceeds the values predicted by a linear fit between foF2 and F10.7. Trends become more negative again when solar cycle 23 minimum is included, since for this period, foF2 is systematically lower than values predicted by the linear fit. foF2 trends assessed with modeled foF2 values are less strong than those obtained with experimental foF2 values and more stable as solar cycle 23 is included in the trend estimation. Modeled trends may be thought of as a ‘zero level’ trend due to the assumptions made in the process of trend estimation considering also that we are not dealing with ideal conditions or infinite time series.Fil: Elias, Ana Georgina. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnologia. Departamento de Fisica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: de Haro Barbás, Blas F.. Universidad Nacional de Tucuman. Facultad de Ciencias Exactas y Tecnologia. Departamento de Fisica; ArgentinaFil: Shibasaki, Kiyoto . Nobeyama Solar Radio Observatory; JapónFil: Souza, Jonas R.. Centro de Previsao de Tempo E Estudos Climaticos. Instituto Nacional de Pesquisas Espaciais; Brasi

First-principles study on the origin of large thermopower in hole-doped LaRhO3 and CuRhO2

Based on first-principles calculations, we study the origin of the large thermopower in Ni-doped LaRhO3 and Mg-doped CuRhO2. We calculate the band structure and construct the maximally localized Wannier functions from which a tight binding Hamiltonian is obtained. The Seebeck coefficient is calculated within the Boltzmann's equation approach using this effective Hamiltonian. For LaRhO3, we find that the Seebeck coefficient remains nearly constant within a large hole concentration range, which is consistent with the experimental observation. For CuRhO2, the overall temperature dependence of the calculated Seebeck coefficient is in excellent agreement with the experiment. The origin of the large thermopower is discussed.Comment: 7 pages, to be published J. Phys.: Cond. Matt., Proc. QSD 200

Status Report of LNS Accelerator Complex in 2001(IV. Status Report of LNS Accelerator Complex in 2001)

The electron accelerator complex at the Laboratory of Nuclear Science, Tohoku University has been operated for various fields of science. A 35-year-old 300 MeV electron linac is still working well. However troubles due to aging is rapidly getting serious. In addition, because of multi-purpose use of the linac many different beam characteristics are requested by the users, so that the operation mode has been complicate. In this report, the operation status of the accelerator complex including major troubles experienced in the fiscal year 2001 is described and future plan is shortly discussed by showing the present machine operation

Status Report of LNS Accelerator Complex in 2002(IV. Status Report of LNS Accelerator Complex in 2002)

Operation status of an electron accelerator complex at Laboratory of Nuclear Science, Tohoku University is reported. After a completion of a new building containing an experimental vault, the inspection for the radiation safety was done in the beginning of October, 2003, so that most of user machine time was consumed in the latter half of the fiscal year 2002

Photomyogenic response in Niemann–Pick type C: a case report

Contains fulltext : 98214.pdf (publisher's version ) (Closed access)1 maart 201

Nomenclature of Genetically Determined Myoclonus Syndromes:Recommendations of the International Parkinson and Movement Disorder Society Task Force

Genetically determined myoclonus disorders are a result of a large number of genes. They have wide clinical variation and no systematic nomenclature. With next-generation sequencing, genetic diagnostics require stringent criteria to associate genes and phenotype. To improve (future) classification and recognition of genetically determined movement disorders, the Movement Disorder Society Task Force for Nomenclature of Genetic Movement Disorders (2012) advocates and renews the naming system of locus symbols. Here, we propose a nomenclature for myoclonus syndromes and related disorders with myoclonic jerks (hyperekplexia and myoclonic epileptic encephalopathies) to guide clinicians in their diagnostic approach to patients with these disorders. Sixty-seven genes were included in the nomenclature. They were divided into 3 subgroups: prominent myoclonus syndromes, 35 genes; prominent myoclonus syndromes combined with another prominent movement disorder, 9 genes; disorders that present usually with other phenotypes but can manifest as a prominent myoclonus syndrome, 23 genes. An additional movement disorder is seen in nearly all myoclonus syndromes: ataxia (n = 41), ataxia and dystonia (n = 6), and dystonia (n = 5). However, no additional movement disorders were seen in related disorders. Cognitive decline and epilepsy are present in the vast majority. The anatomical origin of myoclonus is known in 64% of genetic disorders: cortical (n = 34), noncortical areas (n = 8), and both (n = 1). Cortical myoclonus is commonly seen in association with ataxia, and noncortical myoclonus is often seen with myoclonus-dystonia. This new nomenclature of myoclonus will guide diagnostic testing and phenotype classification. (c) 2019 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society

Differences in serum IL-6 response after 1°C rise in core body temperature in individuals with spinal cord injury and cervical spinal cord injury during local heat stress

Objectives: Passive rise in core body temperature achieved by head-out hot water immersion (HHWI) results in acute increases in serum interleukin (IL)-6 but no change in plasma adrenaline in patients with cervical spinal cord injury (CSCI). The purpose of the present study was to determine the mechanism of heat stress-induced increase in serum IL-6. Setting: A cross-sectional study. Methods: The study subjects were 9 with CSCI, 10 with thoracic and lumbar spinal cord injury (TLSCI) and 8 able-bodied (AB) subjects. Time since injury was 16.4±4.1 years in TLSCI and 16.1±3.4 years in CSCI. Subjects were subjected to lower-body heat stress (LBH) by wearing a hot water-perfused suit until 1°C increase in core temperature. The levels of serum IL-6, plasma adrenaline, tumor necrosis factor (TNF)-α, C-reactive protein (CRP), and counts of blood cells were measured at normothermia and after LBH. Results: Serum IL-6 concentrations increased significantly immediately after LBH in all the three groups. ΔIL-6% was lower in CSCI subjects compared with AB subjects. Plasma adrenaline concentrations significantly increased after LBH in AB and TLSCI subjects, but did not change throughout the study in CSCI subjects. Cardiac output and heart rate increased at the end of LBH in all three groups. Conclusion: Under a similar increase in core temperature, ΔIL-6% was lower in the CSCI group compared with the AB group. These findings suggest that the observed rise in IL-6 during hyperthermia is mediated, at least in part, by plasma adrenaline

Rab3D is critical for secretory granule maturation in PC12 cells.

Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex. This maturation process is characterized by acidification-dependent processing of cargo proteins, condensation of the SG matrix and removal of membrane and proteins not destined to mature secretory granules (MSGs). Here we addressed a potential role of Rab3 isoforms in these maturation steps by expressing their nucleotide-binding deficient mutants in PC12 cells. Our data show that the presence of Rab3D(N135I) decreases the restriction of maturing SGs to the F-actin-rich cell cortex, blocks the removal of the endoprotease furin from SGs and impedes the processing of the luminal SG protein secretogranin II. This strongly suggests that Rab3D is implicated in the subcellular localization and maturation of ISGs