Generation of Molecular Complexity from Cyclooctatetraene: Preparation of Aminobicyclo[5.1.0]octitols

A series of eight stereoisomeric N-(tetrahydroxy bicyclo-[5.1.0]oct-2S*-yl)phthalimides were prepared in one to four steps from N-(bicyclo[5.1.0]octa-3,5-dien-2-yl)phthalimide (±)-7, which is readily available from cyclooctatetraene (62 % yield). The structural assignments of the stereoisomers were established by 1H NMR spectral data as well as X-ray crystal structures for certain members. The outcomes of several epoxydiol hydrolyses, particularly ring contraction and enlargement, are of note. The isomeric phthalimides as well as the free amines did not exhibit β-glucosidase inhibitory activity at a concentration of less than 100 μM

Evaluating the Baluti Formation at Sararu village, Ora Anticline, Iraqi Kurdistan : a stratigraphic and geochemical approach

Open access through Springer Compact Agreement Acknowledgements The authors would like to thank Colin Taylor and Walter Ritchie from University of Aberdeen for their technical support and assistance with laboratory work. We would also like to thank Mr. Omer Kamil Ali, the Head of the Qumri village, for providing accommodation during fieldwork.Peer reviewedPublisher PD

Optical study of the vibrational and dielectric properties of BiMnO3

BiMnO3 (BMO), ferromagnetic (FM) below Tc = 100 K, was believed to be also ferroelectric (FE) due to a non-centro-symmetric C2 structure, until diffraction data indicated that its space group is the centro-symmetric C2/c. Here we present infrared phonon spectra of BMO, taken on a mosaic of single crystals, which are consistent with C2/c at any T > 10 K, as well as room-temperature Raman data which strongly support this conclusion. We also find that the infrared intensity of several phonons increases steadily for decreasing T, causing the relative permittivity of BMO to vary from 18.5 at 300 K to 45 at 10 K. At variance with FE materials of displacive type, no appreciable softening has been found in the infrared phonons. Both their frequencies and intensities, moreover, appear insensitive to the FM transition at Tc

Systems, methods and computer program products for prediction of defect-related failures in integrated circuits

Systems, methods and computer program products for predicting defect-related failures in integrated circuits produced by an integrated circuit fabrication process identify objects in a circuit layout for the integrated circuit design, each object having a location in the circuit layout and a reliability connectivity in the integrated circuit design. Sample object defects are generated for the identified objects, each sample object defect representing a defect produced in an object by the integrated circuit fabrication process and having a defect magnitude associated therewith. An accelerated life defect influence model is identified for each sample object defect, relating the lifetime of an object to the defect magnitude of a defect in the object. Sample object lifetimes are generated from the defect magnitudes associated with the sample object defects according to the corresponding identified accelerated life defect influence models. A prediction of the reliability of integrated circuits is generated from the sample object lifetimes according to the reliability connectivity of the associated objects in the integrated circuit design. Preferably, the accelerated life defect influence models include log-linear regression models, which may include deterministic object lifetime functions, each relating the defect magnitude of the at least one sample object defect to one object lifetime value, and log-linear object lifetime distributions, each relating the defect magnitude of a sample object defect to a plurality of object lifetime values

Evaluating the In vivo Efficacy of Copper-Chitosan Nanocomposition for Treating Vascular Wilt Disease in Date Palm

Date palm, Phoenix dactylifera, as one of the most important fruit crops in Egypt and many other countries, can be affected by many fungal diseases, among which the vascular wilt disease, caused by the fungal pathogen Fusarium oxysporum, is considered the most deteriorating one. This study aims at evaluating the efficiency of Copper-Chitosan Nanopcomposition for treating the vascular wilt disease in date palm. The study relies mainly on beleaguering the disease via the double-role functionality of copper-chitosan nanocomposition, i.e. its potential antifungal effect on the fungal pathogen, besides its capability to enhance the immune responses of the infected plant. In this regard, chitosan nanoparticles were prepared according to the ionic gelation method, whereas copper nanoparticles were prepared according to the chemical reduction method. Physicochemical characterization of both chitosan and copper nanoparticles was performed using dynamic light scattering (DLS), transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FTIR) and x-ray diffraction (XRD). Copper-chitosan nanocomposition could significantly reduce the vascular wilt disease severity; this means that the nanocomposition can be used in the future for developing new nano-fungicides to control such pathogens

Using High Dimensional Computing on Arabic Language Speech to Text Classification

High-Dimensional Processing is the idea that mind register illustrations of neural activities which are not immediately related with numbers. The objective of the article is hyper- dimensional computation of data for categorization of text from two distinct speech datasets, namely the Arabic Corpus dataset and the MediaSpeech dataset with four languages (Arabic, Spanish, French, and Turkish). Through the use of an n-gram encoding scheme, hyper dimensional computing is used to conduct the analysis from the prior set of data. Using hyper dimensional computing, the MediaSpeech dataset accomplishes 100% accuracy for all 4-gram to 14-gram encoding schemes, while the Arabic Corpus dataset accomplishes 100% accuracy for 4-gram to 7-gram encoding schemes

Prevalence, Electron Microscopy and Molecular Characterization of Cryptosporidium species Infecting Sheep in Egypt

Cryptosporidium sp. is predominant universally and sheep are an imperative zoonotic supply of the disease. Owing to the little information presented with respect to Cryptosporidium sp. infecting sheep, this study was directed to survey the predominance and molecular characterization of Cryptosporidium sp. among sheep of different ages and sexes in Qalyubia governorate, Egypt. The fecal specimens were gathered from 432 sheep of various ages (≤1 to <6, 6-12 and >12 months) and sexes. The samples were microscopically examined after staining by modified Zeihl- Neelsen technique and the intestinal mucosa was scanned by electron microscopy. A nested PCR was connected to amplify a 830 bp of 18S rRNA sequence of Cryptosporidium. RFLP (restriction fragment length polymorphism) technique using SspI and VspI enzymes for digestion of the secondary product of PCR for species identification was applied. The total infection rate was 25.93%. The parasite was more prevalent in males than females of different age groups. Two zoonotic Cryptosporidium species were distinguished after RFLP-PCR sequencing: C. parvum and C. ubiquitum (identified previously as Cervine genotype). The finding recommends that sheep must be considered as a noteworthy potential source of human cryptosporidiosis. A strict reconnaissance of zoonotic cryptosporidiosis must be set up to counteract human infection and to assess forthcoming disease when applying control programs