Encapsulation process sterilizes and preserves surgical instruments

Ethylene oxide is blended with an organic polymer to form a sterile material for encapsulating surgical instruments. The material does not bond to metal and can be easily removed when the instruments are needed

Process for preparing sterile solid propellants Patent

Using ethylene oxide in preparation of sterilized solid rocket propellants and encapsulating material

Practical approach to diastolic dysfunction in light of the new guidelines and clinical applications in the operating room and in the intensive care

There is growing evidence both in the perioperative period and in the field of intensive care (ICU) on the association between left ventricular diastolic dysfunction (LVDD) and worse outcomes in patients. The recent American Society of Echocardiography and European Association of Cardiovascular Imaging joint recommendations have tried to simplify the diagnosis and the grading of LVDD. However, both an often unknown pre-morbid LV diastolic function and the presence of several confounders—i.e., use of vasopressors, positive pressure ventilation, volume loading—make the proposed parameters difficult to interpret, especially in the ICU. Among the proposed parameters for diagnosis and grading of LVDD, the two tissue Doppler imaging-derived variables e′ and E/e′ seem most reliable. However, these are not devoid of limitations. In the present review, we aim at rationalizing the applicability of the recent recommendations to the perioperative and ICU areas, discussing the clinical meaning and echocardiographic findings of different grades of LVDD, describing the impact of LVDD on patients’ outcomes and providing some hints on the management of patients with LVDD

Survival of microorganisms in desert soil exposed to five years of continuous very high vacuum

Microorganism survivability in desert algal soil crust under continuous very high vacuu

Extracorporeal CO2 removal in hypercapnic patients who fail noni nvasive ventialtion and refuse endotracheal intubation. a case series

Noninvasive ventilation (NIV) represents the standard of care for patients with exacerbation of chronic obstructive pulmonary disease. However, NIV fails in almost 40% of the most severe forms of acute hypercapnic respiratory failure and patients must undergo endotracheal intubation and invasive ventilation. Such transition from NIV to invasive ventilation is associated to increased mortality. Under these circumstances, patients may express a clear intention not to be intubated

IMAGE ORIENTATION WITH A HYBRID PIPELINE ROBUST TO ROTATIONS AND WIDE-BASELINES

The extraction of reliable and repeatable interest points among images is a fundamental step for automatic image orientation (Structure-From-Motion). Despite recent progresses, open issues in challenging conditions - such as wide baselines and strong light variations - are still present. Over the years, traditional hand-crafted methods have been paired by learning-based approaches, progressively updating the state-of-the-art according to recent benchmarks. Notwithstanding these advancements, learning-based methods are often not suitable for real photogrammetric surveys due to their lack of rotation invariance, a fundamental requirement for these specific applications. This paper proposes a novel hybrid image matching pipeline which employs both hand-crafted and deep-based components, to extract reliable rotational invariant keypoints optimized for wide-baseline scenarios. The proposed hybrid pipeline was compared with other hand-crafted and learning-based state-of-the-art approaches on some photogrammetric datasets using metric ground-truth data. Results show that the proposed hybrid matching pipeline has high accuracy and appeared to be the only method among the evaluated ones able to register images in the most challenging wide-baseline scenarios

Statistical Dynamics of Religions and Adherents

Religiosity is one of the most important sociological aspects of populations. All religions may evolve in their beliefs and adapt to the society developments. A religion is a social variable, like a language or wealth, to be studied like any other organizational parameter. Several questions can be raised, as considered in this study: e.g. (i) from a ``macroscopic'' point of view : How many religions exist at a given time? (ii) from a ``microscopic'' view point: How many adherents belong to one religion? Does the number of adherents increase or not, and how? No need to say that if quantitative answers and mathematical laws are found, agent based models can be imagined to describe such non-equilibrium processes. It is found that empirical laws can be deduced and related to preferential attachment processes, like on evolving network; we propose two different algorithmic models reproducing as well the data. Moreover, a population growth-death equation is shown to be a plausible modeling of evolution dynamics in a continuous time framework. Differences with language dynamic competition is emphasized.Comment: submitted to EP

Analysis of an intense bora event in the Adriatic area

International audienceNumerical simulations of a bora event, recently occurred in the Adriatic area, are presented. Two reference runs at different horizontal resolution (about 20km and 8km) describe the case. Initial conditions for the atmospheric model integration are obtained from ECMWF analyses. Satellite data are used for comparisons. A further run at horizontal resolution of 8km, using initial satellite sea surface temperatures, is performed to evaluate their impact on the low level wind over the Adriatic Sea. All the simulations are carried out with 50 layers in the vertical. Numerous aspects of the simulations are found to be in agreement with the understanding as well as the observational knowledge of bora distinctive characteristics. Satellite data and model results indicate that a more realistic simulation of the bora wind over the sea is achieved using the model with 8km horizontal resolution and that the low level wind in this case is sensitive, though weakly, to the difference between the used sea surface temperature fields. Simulation results also show that both wind intensity and the area around wind peaks tend to increase when relatively higher sea surface temperatures are used

Optimal cellular mobility for synchronization arising from the gradual recovery of intercellular interactions

Cell movement and intercellular signaling occur simultaneously during the development of tissues, but little is known about how movement affects signaling. Previous theoretical studies have shown that faster moving cells favor synchronization across a population of locally coupled genetic oscillators. An important assumption in these studies is that cells can immediately interact with their new neighbors after arriving at a new location. However, intercellular interactions in cellular systems may need some time to become fully established. How movement affects synchronization in this situation has not been examined. Here we develop a coupled phase oscillator model in which we consider cell movement and the gradual recovery of intercellular coupling experienced by a cell after movement, characterized by a moving rate and a coupling recovery rate respectively. We find (1) an optimal moving rate for synchronization, and (2) a critical moving rate above which achieving synchronization is not possible. These results indicate that the extent to which movement enhances synchrony is limited by a gradual recovery of coupling. These findings suggest that the ratio of time scales of movement and signaling recovery is critical for information transfer between moving cells.Comment: 18 single column pages + 1 table + 5 figures + Supporting Informatio