511 research outputs found

    Digital Platforms for Renewable Energy Communities Projects: An Overview

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    The European Union energy policy agenda of achieving the transition to carbon neutrality has been established by an important legislative package called "Clean Energy for all Europeans". A novel approach introduced was to put the citizen at the center of the energy transition. On one side, by powering his freedom of action and, on the other side, by asking him an exceptional engagement in energy consumption reduction activities and in participating in the investments for new distributed Renewable Energy Sources (RES) power plants. The Renewable Energy Communities (REC) is the policy framework used to implement this strategy introduced by the Renewable Energy Directive Recast (RED II). In particular, RECs promote citizen’s active role by encouraging energy consumption reduction and energy demand flexibility while reducing the Not In My Bachyard (NIMBY) effect towards RES. Each member state is transposing the RED II directive, adapting it to national legislation and energy transition strategy. Pioneers countries like Italy have already started the experimentation of this framework and developing the first pilot projects. The citizens’ interest and their will to participate in REC projects indicate the need for supporting tools guiding them along all the project development stages: “design”, “creation”, and “operation”. This work presents three categories of supporting digital tools and platforms required to develop REC projects: Commercial, EU Founded and Freeware. We analyzed 30 tools, evaluating the services provided in each of the different stages of REC project implementation

    Techno-economic comparison of buildings acting as Single-Self Consumers or as energy community through multiple economic scenarios

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    The European Union has set ambitious targets to move towards a society with high penetration of renewable energy sources. In the forthcoming energy transition, Energy Communities (EC), i.e., legal entities where different actors, including citizens, cooperate in energy generation, storage and management, will play a crucial role. The present work simulates the energy flows and assesses the potential economic benefits of a cluster of buildings acting collectively as an energy community – a specific case study is set in northern Italy by comparing the EC performance with a configuration where customers act as Single Self-Consumers (SSCs). Pending the transposition of EU Directives to binding national laws, due by 2021, different supporting tariffs (economic scenarios) have been simulated in order to determine which scheme will support more effectively the integration of Energy Communities in the national energy market. Results show that ECs (i.e., customers acting collectively as energy prosumers) are able to accelerate the diffusion of building-integrated renewable energy sources (RES), resulting in higher overall self-consumption rates than SSCs. Self-consumed electricity generates savings on the energy bill of EC, and we calculated positive economic performance indicators for all the analysed economic scenarios. The sensitivity analysis carried out on system and transport charges of the electricity bill shows their remarkable impact on the economics making the EC less attractive for investors and citizens without proper supporting schemes

    Cross talk: the microbiota and neurodevelopmental disorders

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    Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut microbiota can signal to the brain via the immune system, the vagus nerve or other host-microbe interactions facilitated by gut hormones, regulation of tryptophan metabolism and microbial metabolites such as short chain fatty acids (SCFA), to influence brain development, function and behavior. Emerging evidence suggests that the gut microbiota may play a role in shaping cognitive networks encompassing emotional and social domains in neurodevelopmental disorders. Drawing upon pre-clinical and clinical evidence, we review the potential role of the gut microbiota in the origins and development of social and emotional domains related to Autism spectrum disorders (ASD) and schizophrenia. Small preliminary clinical studies have demonstrated gut microbiota alterations in both ASD and schizophrenia compared to healthy controls. However, we await the further development of mechanistic insights, together with large scale longitudinal clinical trials, that encompass a systems level dimensional approach, to investigate whether promising pre-clinical and initial clinical findings lead to clinical relevance

    EXPO-AGRI: Smart Automatic Greenhouse Control

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    Predicting and controlling plant behavior in con- trolled environments is a growing requirement in precision agri- culture. In this context sensor networks and artificial intelligence methods represent key aspects for optimizing the processes of data acquisition, mathematical modeling and decision making. In this paper we present a general architecture for automatic greenhouse control. In particular, we focus on a preliminary model for predicting the risk of new infections of downy mildew of basil (Peronospora belbahrii) on sweet basil. The architecture has three main elements of innovation: new kinds of sensors are used to extract information about the state of the plants, model predictors are generated from this information by non-trivial processing methods, and informative predictors are automatically selected using regularization techniques

    The Metabolic Profile in Active Acromegaly is Gender-Specific.

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    CONTEXT: The sexual dimorphism of the somatotroph axis has been documented, but whether the acromegaly-related metabolic alterations are gender-dependent has never been investigated. OBJECTIVE: The aim of the study was to evaluate the impact of gender on the metabolic parameters in acromegaly. DESIGN: We conducted a retrospective, comparative, multicenter study. PATIENTS: The 307 newly diagnosed acromegalic patients included in the study were grouped by gender: 157 men (aged 48.01 ± 14.28 yr), and 150 women (aged 48.67 ± 14.95 yr; of which 77 were premenopausal and 73 postmenopausal). OUTCOME MEASUREMENTS: We measured each component of the metabolic syndrome (MS), hemoglobin A1c, the areas under the curve (AUCs) of glucose and insulin during 2-h oral glucose tolerance test, basal insulin resistance using the homeostasis model assessment of the insulin resistance index, stimulated insulin sensitivity using the insulin sensitivity index, early insulin-secretion rate using the insulinogenic index, ÎČ-cell function relative to insulin sensitivity using the oral disposition index and the visceral adiposity index (VAI) as the surrogate of visceral fat function. RESULTS: Women showed a higher prevalence of MS (P < 0.001), higher fasting insulin levels (P < 0.001), AUC for insulin (P = 0.002), homeostasis model assessment of the insulin resistance index (P < 0.001), and VAI (P < 0.001) and a lower insulin sensitivity index (P = 0.002) than men, whereas no difference was found in fasting glucose, AUC for glucose, hemoglobin A1c, insulinogenic index, and oral disposition index. In women, fasting glucose and fasting insulin showed a significant trend toward increase (P < 0.001) and decrease (P = 0.004), respectively, from the first to the fourth quartiles of age, whereas VAI showed a trend toward increase in both groups (P < 0.001). A significantly higher prevalence of MS (P < 0.001), increased waist circumference (P < 0.001), low high-density lipoprotein cholesterol (P < 0.001), and overt diabetes mellitus (P < 0.001) was found in postmenopausal women compared with premenopausal women, as well as with men. CONCLUSIONS: The majority of metabolic features in acromegaly are gender-specific. Active acromegaly in women is strongly associated with higher visceral adiposity dysfunction, insulin resistance, and the features of MS. We suggest more accurate metabolic management in acromegalic women, especially in the postmenopausal years

    Results of the fifth international spectroradiometer comparison for improved solar spectral irradiance measurements and related impact on reference solar cell calibration

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    This paper reports on the results of the fifth spectral irradiance measurement intercomparison and the impact these results have on the spread of spectral mismatch calculations in the outdoor characterization of reference solar cell and photovoltaic (PV) devices. Ten laboratories and commercial partners with their own instruments were involved in the comparison. Solar spectral irradiance in clear sky condition was measured with both fast fixed and slow rotating grating spectroradiometers. This paper describes the intercomparison campaign, describes different statistical analysis used on acquired data, reports on the results, and analyzes the impact these results would have on the primary calibration of a c-Si PV reference cell under natural sunlight

    Wolfram Syndrome (Diabetes Insipidus, Diabetes, Optic Atrophy, and Deafness): Clinical and genetic study

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    OBJECTIVE—Wolfram syndrome is an autosomal recessive neurodegenerative disorder characterized by diabetes insipidus, diabetes (nonautoimmune), optic atrophy, and deafness (a set of conditions referred to as DIDMOAD). The WFS1 gene is located on the short arm of chromosome 4. Wolfram syndrome prevalence is 1 in 770,000 live births, with a 1 in 354 carrier frequency

    Maturity-Onset Diabetes of the Young in Children With Incidental Hyperglycemia:: A multicenter Italian study of 172 families

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    OBJECTIVE - To investigate the prevalence of maturity-onset diabetes of the young (MODY) in Italian children With incidental hyperglycemia. RESEARCH DESIGN AND METHODS - Among 748 subjects age 1-18 years with incidental hyperglycemia, minimal diagnostic criteria for MODY were met by 172 families. Mutational analyses of the glucokinase (GCK) and hepatocyte nuclear factor lot (HNF1A) genes were performed. RESULTS - We identified 85 GCK gene mutations in 109 probands and 10 HNF1A mutations in 12 probands. In GCK patients, the median neonatal weight and age at the first evaluation were lower than those found in patients with HNF1A mutations. Median fasting plasma glucose and impaired fasting glucose/impaired glucose tolerance frequency after oral glucose tolerance testing were higher in GCK patients, who also showed a lower frequency of diabetes than HNF1A patients. CONCLUSIONS - GCK mutations are the prevailing cause of MODY (63.4%) when the index case is recruited in Italian children with incidental hyperglycemia
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