Crickets.

2 p

Lompat Jauh dengan Menggunakan Modifikasi Kardus di Sdn 21 Sungai Ayak

This study aims to determine whether there is an increased jump cardboard game against the squat -style long jump results in Class IV SDN 21 Sungai Ayak Sekadau . research subjects are teachers collaborate with fourth grade students of SDN 21 Sungai Ayak Kabupaten Sekadau as many as 27 students . Learning the long jump with mediakardus provide convenience to the students to always be active and brave movement high jump is easy and fun give suasanan new that has never been done before , the positive impact of such students do not experience fear , feel good and appropriate to the capabilities students . In making value starts prasiklus , the first cycle ( 20 students ) and the second cycle ( 27 students ) have increased systematicall

A Computationally-Efficient Probabilistic Approach to Model-Based Damage Diagnosis

This work presents a computationally-efficient, probabilistic approach to model-based damage diagnosis. Given measurement data, probability distributions of unknown damage parameters are estimated using Bayesian inference and Markov chain Monte Carlo (MCMC) sampling. Substantial computational speedup is obtained by replacing a three-dimensional finite element (FE) model with an efficient surrogate model. While the formulation is general for arbitrary component geometry, damage type, and sensor data, it is applied to the problem of strain-based crack characterization and experimentally validated using full-field strain data from digital image correlation (DIC). Access to full-field DIC data facilitates the study of the effectiveness of strain-based diagnosis as the distance between the location of damage and strain measurements is varied. The ability of the framework to accurately estimate the crack parameters and effectively capture the uncertainty due to measurement proximity and experimental error is demonstrated. Furthermore, surrogate modeling is shown to enable diagnoses on the order of seconds and minutes rather than several days required with the FE model

Crickets.

2 p

An Investigation of Somali Women’s Beliefs, Practices, and Attitudes about Health, Health Promoting Behaviours and Cancer Prevention

This pilot study examined Somali women's perception of health/access to care, examined their knowledge and attitudes about cancer prevention, and discussed strategies to improve service provision and education. Using a multidisciplinary approach, twelve face-to-face interviews were conducted with Somali women ages 18 and older, residing in a mid-western city. Open coding was used to categorize and reflect the interview statements and to identify reoccurring themes. Somali women are concerned about a variety of health issues and cited the role of culture and religion in developing prevention strategies.   Participants emphasized the use of religious leaders, health care advocates, oral traditions, and translators in providing culturally appropriate health care services. Religion and culture play a prominent role in the Somali community and impact beliefs about health and wellness.  Health practitioners need to work closely with individuals and community leaders to tailor services that are culturally appropriate and accessible.     

IMPACT OF A MORE INTENSIVE INSECT PEST INFESTATION LEVEL ON COTTON PRODUCTION: TEXAS HIGH PLAINS

This study evaluated implications of increased bollworm problems in a 20-county area of the Texas High Plains relative to cotton yields and economic impact. Results did not indicate a serious effect of bollworms upon lint yield when insecticides were used for control. However, estimated annual reduction in farmer profit due to the bollworm for 1979-81 was over $30 million. Yields were estimated to decline about 300,000 bales without insecticide use and about 30,000 bales with insecticide use. This decline suggests potentially serious implications for the comparative economic position of cotton in this region if insecticide resistance were to develop among insect pests.Crop Production/Industries,

Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance

Progression and disease relapse of chronic myeloid leukemia (CML) depends on leukemia-initiating cells (LIC) that resist treatment. Using mouse genetics and a BCR-ABL model of CML, we observed cross talk between Wnt/{beta}-catenin signaling and the interferon-regulatory factor 8 (Irf8). In normal hematopoiesis, activation of {beta}-catenin results in up-regulation of Irf8, which in turn limits oncogenic {beta}-catenin functions. Self-renewal and myeloproliferation become dependent on {beta}-catenin in Irf8-deficient animals that develop a CML-like disease. Combined Irf8 deletion and constitutive {beta}-catenin activation result in progression of CML into fatal blast crisis, elevated leukemic potential of BCR-ABL-induced LICs, and Imatinib resistance. Interestingly, activated {beta}-catenin enhances a preexisting Irf8-deficient gene signature, identifying {beta}-catenin as an amplifier of progression-specific gene regulation in the shift of CML to blast crisis. Collectively, our data uncover Irf8 as a roadblock for {beta}-catenin-driven leukemia and imply both factors as targets in combinatorial therapy

Preliminary evaluation of the CellFinder literature curation pipeline for gene expression in kidney cells and anatomical parts

Biomedical literature curation is the process of automatically and/or manually deriving knowledge from scientific publications and recording it into specialized databases for structured delivery to users. It is a slow, error-prone, complex, costly and, yet, highly important task. Previous experiences have proven that text mining can assist in its many phases, especially, in triage of relevant documents and extraction of named entities and biological events. Here, we present the curation pipeline of the CellFinder database, a repository of cell research, which includes data derived from literature curation and microarrays to identify cell types, cell lines, organs and so forth, and especially patterns in gene expression. The curation pipeline is based on freely available tools in all text mining steps, as well as the manual validation of extracted data. Preliminary results are presented for a data set of 2376 full texts from which >4500 gene expression events in cell or anatomical part have been extracted. Validation of half of this data resulted in a precision of ~50% of the extracted data, which indicates that we are on the right track with our pipeline for the proposed task. However, evaluation of the methods shows that there is still room for improvement in the named-entity recognition and that a larger and more robust corpus is needed to achieve a better performance for event extraction. Database URL: http://www.cellfinder.org