10,761 research outputs found

    A Z_3-graded generalization of supermatrices

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    We introduce Z_3-graded objects which are the generalization of the more familiar Z_2-graded objects that are used in supersymmetric theories and in many models of non-commutative geometry. First, we introduce the Z_3-graded Grassmann algebra, and we use this object to construct the Z_3-matrices, which are the generalizations of the supermatrices. Then, we generalize the concepts of supertrace and superdeterminant

    Synchronous Behavior of Two Coupled Electronic Neurons

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    We report on experimental studies of synchronization phenomena in a pair of analog electronic neurons (ENs). The ENs were designed to reproduce the observed membrane voltage oscillations of isolated biological neurons from the stomatogastric ganglion of the California spiny lobster Panulirus interruptus. The ENs are simple analog circuits which integrate four dimensional differential equations representing fast and slow subcellular mechanisms that produce the characteristic regular/chaotic spiking-bursting behavior of these cells. In this paper we study their dynamical behavior as we couple them in the same configurations as we have done for their counterpart biological neurons. The interconnections we use for these neural oscillators are both direct electrical connections and excitatory and inhibitory chemical connections: each realized by analog circuitry and suggested by biological examples. We provide here quantitative evidence that the ENs and the biological neurons behave similarly when coupled in the same manner. They each display well defined bifurcations in their mutual synchronization and regularization. We report briefly on an experiment on coupled biological neurons and four dimensional ENs which provides further ground for testing the validity of our numerical and electronic models of individual neural behavior. Our experiments as a whole present interesting new examples of regularization and synchronization in coupled nonlinear oscillators.Comment: 26 pages, 10 figure

    Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections.

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    The innate immune system recalls a challenge to adapt to a secondary challenge, a phenomenon called trained immunity. Training involves cellular metabolic, epigenetic and functional reprogramming, but how broadly trained immunity protects from infections is unknown. For the first time, we addressed whether trained immunity provides protection in a large panel of preclinical models of infections. Mice were trained and subjected to systemic infections, peritonitis, enteritis, and pneumonia induced by Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Citrobacter rodentium, and Pseudomonas aeruginosa. Bacteria, cytokines, leukocytes, and hematopoietic precursors were quantified in blood, bone marrow, and organs. The role of monocytes/macrophages, granulocytes, and interleukin 1 signaling was investigated using depletion or blocking approaches. Induction of trained immunity protected mice in all preclinical models, including when training and infection were initiated in distant organs. Trained immunity increased bone marrow hematopoietic progenitors, blood Ly6Chigh inflammatory monocytes and granulocytes, and sustained blood antimicrobial responses. Monocytes/macrophages and interleukin 1 signaling were required to protect trained mice from listeriosis. Trained mice were efficiently protected from peritonitis and listeriosis for up to 5 weeks. Trained immunity confers broad-spectrum protection against lethal bacterial infections. These observations support the development of trained immunity-based strategies to improve host defenses

    Mapping of shape invariant potentials by the point canonical transformation

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    In this paper by using the method of point canonical transformation we find that the Coulomb and Kratzer potentials can be mapped to the Morse potential. Then we show that the P\"{o}schl-Teller potential type I belongs to the same subclass of shape invariant potentials as Hulth\'{e}n potential. Also we show that the shape-invariant algebra for Coulomb, Kratzer, and Morse potentials is SU(1,1), while the shape-invariant algebra for P\"{o}schl-Teller type I and Hulth\'{e}n is SU(2)

    Photoassociative Production and Trapping of Ultracold KRb Molecules

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    We have produced ultracold heteronuclear KRb molecules by the process of photoassociation in a two-species magneto-optical trap. Following decay of the photoassociated KRb*, the molecules are detected using two-photon ionization and time-of-flight mass spectroscopy of KRb+^+. A portion of the metastable triplet molecules thus formed are magnetically trapped. Photoassociative spectra down to 91 cm1^{-1} below the K(4ss) + Rb (5p1/2p_{1/2}) asymptote have been obtained. We have made assignments to all eight of the attractive Hund's case (c) KRb* potential curves in this spectral region.Comment: 4 pages, 4 figure

    Risk analysis of marine activities in the Belgian part of the North Sea (RAMA): final report

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    RAMA is a 2-year project (04/2004 - 04/2006) executed by two Belgian partners, Ecolas NV (Environmental Consultancy Agency) and the Maritime Institute (University of Ghent), and financed by the SPSD II research program, specific actions, of the Belgian Science Policy (BELPSO). RAMA aims to assess the environmental risks of spills by commercial shipping activities on the Belgian Part of the North Sea. Shipping patterns, transports of dangerous goods, probability of risks and the potential impact of spill incidents (oil & hazardous and noxious substances) will be assessed. The risk analysis within this project studies both the chances of a spill accident happening and the environmental impacts in case of an accident. The valorisation of the RAMA project will result in a thorough analysis of the current status of the shipping at the North Sea in relation to the issue of safety. The scope of the project will however go beyond the mere result of a fundamental risk analysis of the commercial shipping at the North Sea. It is also aiming at the formulation of recommendations to improve the safety level for the environment and at an optimization of response in the framework of the Belgian "North Sea Disaster Plan"

    Polarization tomography of metallic nanohole arrays

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    We report polarization tomography experiments on metallic nanohole arrays with square and hexagonal symmetry. As a main result, we find that a fully polarized input beam is partly depolarized after transmission through a nanohole array. This loss of polarization coherence is found to be anisotropic, i.e. it depends on the polarization state of the input beam. The depolarization is ascribed to a combination of two factors: i) the nonlocal response of the array due to surface plasmon propagation, ii) the non-plane wave nature of a practical input beam.Comment: 4 pages, 3 figures, 1 table, submitted to PR
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