901 research outputs found
primary cutaneous cd30 anaplastic large cell lymphoma in a heart transplant patient case report and literature review
Solid organ transplant recipients are at risk of develop ing a wide range of viral-associated malignancies, in cluding skin tumours and lymphoproliferative disorders. The risk of a post-transplant lymphoproliferative disorder is 28–49 times the risk of a lymphoproliferative disorder in the normal population. Most cases are of B-cell phenotype and are associated with Epstein-Barr virus infection. Post-transplant lymphoproliferative disorders presenting clinically in the skin are rare and usually of B-cell phenotype. Only rare cases of cutaneous T-cell post-transplant lymphoproliferative disorder have been reported previously, mostly mycosis fungoides type. We describe here a rare primary cutaneous T-cell lymphoma CD30+ arising in a heart transplant patient who had a nodule on the right leg, several years after heart transplantation. The morphology and immunohistochemical findings were consistent with a CD30+ anaplastic large cell lymphoma with a T-cell phenotype. Excisional biopsy and radiotherapy of the affected area were performed. In this patient, the presence of a solitary lesion and th
Pre-fattening of Manila clams in a Po Delta lagoon: effect of stocking density in suspended lanterns
Arabica Selections with Coffea eugenioides and C. canephora Introgressions for RondĂ´nia State in Brazilian Amazon.
Role of magnetic dopants in the phase diagram of Sm1111 pnictides: The Mn case
The deliberate insertion of magnetic Mn dopants in the Fe sites of the
optimally-doped SmFeAsO0.88-F0.12 iron-based superconductor can modify in a
controlled way its electronic properties. The resulting phase diagram was
investigated across a wide range of manganese contents (x) by means of
muon-spin spectroscopy (muSR), both in zero- and in transverse fields,
respectively, to probe the magnetic and the superconducting order. The pure
superconducting phase (at x < 0.03) is replaced by a crossover region at
intermediate Mn values (0.03 =< x < 0.08), where superconductivity coexists
with static magnetic order. After completely suppressing superconductivity for
x = 0.08, a further increase in Mn content reinforces the natural tendency
towards antiferromagnetic correlations among the magnetic Mn ions. The sharp
drop of Tc and the induced magnetic order in the presence of magnetic
disorder/dopants, such as Mn, are both consistent with a recent theoretical
model of unconventional superconductors [M. Gastiasoro et al., ArXiv
1606.09495], which includes correlation-enhanced RKKY-couplings between the
impurity moments.Comment: 10 pages, 13 figures. Accepted on Physical Review
Effect of Feed Restriction on the Behaviour and Welfare of Broiler Chickens
Under intensive rearing conditions, the welfare of broiler chickens may be at risk
depending on genotype and sex, due to their different growth rates. The practice of quantitative
feed restriction may also impact on welfare. This study aimed to evaluate behaviour and
corticosterone content in plasma and faeces at different ages using 896 one-day-old chicks housed
in 32 pens, allocated to 8 groups, i.e., 2 genotypes (standard vs. high breast yield)
7 2 sex
7 2 feeding
plans (ad libitum vs. restricted, AL vs. FR). The feeding system affected the percentage of standing
(9.84% vs. 11.7% in AL vs. FR; p 64 0.001), feeding (7.51% vs. 8.17%; p 64 0.01) and sitting/lying (67.0%
vs. 64.1%; p 64 0.001), and the faeces corticosterone content (12.2 vs. 13.6 ng/g in AL vs. FR; p 64 0.10).
Sex affected the percentage of pecking other chickens, standing and comfort behaviours. Changes
in behaviour were recorded between high and standard breast yield genotypes with faeces
corticosterone which tended to be higher in the former (p 64 0.10). Significant interactions between the main factors and age were observed. Major changes in behaviour were due to feed restriction,
which stimulated activity during restriction
Factors affecting space use by laying hens in a cage-free aviary system: effect of nest lighting at pullet housing and of curtain nest color during laying
At 17 wk of age, 1,800 Lohman brown hens were housed in 8 pens of an experimental aviary system, specifically set up for the purposes of the present study, and kept until 26 wk without or with nest lighting (lights inside the nest 1.5 h before the lighting of the installation) for training in the nest use. Then, at 27 wk, 4 combinations of nest curtains were adopted to evaluate the effects on hens’ distribution, that is, nests with red (RR) or yellow (YY) curtains at all tiers; nests with red and yellow curtains at the first and second tier, respectively (RY); or nests with yellow and red curtains at the first and second tier, respectively (YR). The use of enlightened compared to dark nests at housing increased
the oviposition rate (P < 0.001) and decreased the rate of broken (P < 0.001) and dirty eggs (P < 0.05) from 27 to 45 wk, while increasing the rate of eggs laid inside the nests (P < 0.001). The presence of yellow nest curtains increased the rate of hens on the floor in pens YY and YR
compared to pens RR and RY (35.3 and 35.5% vs. 34.1 and 33.3%, respectively; P = 0.05) and the rate of floor eggs in pens YR (2.23% vs. 1.63 and 1.65% in pens RR and RY; P < 0.05). In pens RY, a higher rate of eggs was always found on the second tier compared to the first one
with the most inhomogeneous distribution compared to pens RR, YY, and YR (+10.8 vs. +3.4, +1.9, and +4.6 percentage points of eggs laid on the second tier compared to the first one, respectively). In conclusion, nest lighting at housing trained hens to the use of nests while improving egg production in terms of quantity and quality. The use of yellow curtains on nests moved hens between the different
levels of the aviary but this was not associated with an increased nest use for laying
A Joint Venture of Ab Initio Molecular Dynamics, Coupled Cluster Electronic Structure Methods, and Liquid-State Theory to Compute Accurate Isotropic Hyperfine Constants of Nitroxide Probes in Water
The isotropic hyperfine coupling constant (HFCC, Aiso) of a pH-sensitive spin probe in a solution, HMI (2,2,3,4,5,5-hexamethylimidazolidin-1-oxyl, C9H19N2O) in water, is computed using an ensemble of state-of-the-art computational techniques and is gauged against X-band continuous wave electron paramagnetic resonance (EPR) measurement spectra at room temperature. Fundamentally, the investigation aims to delineate the cutting edge of current first-principles-based calculations of EPR parameters in aqueous solutions based on using rigorous statistical mechanics combined with correlated electronic structure techniques. In particular, the impact of solvation is described by exploiting fully atomistic, RISM integral equation, and implicit solvation approaches as offered by ab initio molecular dynamics (AIMD) of the periodic bulk solution (using the spin-polarized revPBE0-D3 hybrid functional), embedded cluster reference interaction site model integral equation theory (EC-RISM), and polarizable continuum embedding (using CPCM) of microsolvated complexes, respectively. HFCCs are obtained from efficient coupled cluster calculations (using open-shell DLPNO-CCSD theory) as well as from hybrid density functional theory (using revPBE0-D3). Re-solvation of “vertically desolvated” spin probe configuration snapshots by EC-RISM embedding is shown to provide significantly improved results compared to CPCM since only the former captures the inherent structural heterogeneity of the solvent close to the spin probe. The average values of the Aiso parameter obtained based on configurational statistics using explicit water within AIMD and from EC-RISM solvation are found to be satisfactorily close. Using either such explicit or RISM solvation in conjunction with DLPNO-CCSD calculations of the HFCCs provides an average Aiso parameter for HMI in aqueous solution at 300 K and 1 bar that is in good agreement with the experimentally determined one. The developed computational strategy is general in the sense that it can be readily applied to other spin probes of similar molecular complexity, to aqueous solutions beyond ambient conditions, as well as to other solvents in the longer run
- …