Sızgıt as a traditional food of Cappadocia: Differences in traditional and commercial production

Sızgıt which is consumed likely and frequently a traditional meat product producing by Cappadocian people. This study aims to determine the physicochemical and microbiological properties of traditional and commercial Sızgıt. pH, lipid oxidation and cholesterol level, protein, fat and moisture content, fatty acid composition, aerobic mesophilic bacteria, enterobacteria, mold and yeast, Staphylococcus aureus and Salmonella counts were determined. Fat and cholesterol content of traditional samples had lower than the commercial samples while the protein content of commercial samples had highest (P<0.05). Saturated fatty acid levels of traditional samples were higher than commercial samples (P<0.05). The highest lipid oxidation values were determined in traditional samples. Salmonella and S. aureus which are pathogenic bacteria were not determined in both types of Sızgıt samples. The results indicated that the public should be informed about food safety and the sensitivity to the production and consumption of these products should be increased. On the other hand, ethnic and traditional characteristics on the production and the storage conditions of the Sızgıt in Cappadocian should be preserved.Nevşehir Hacı Bektaş Veli University, Scientific Research Projects Coordinators (Project No: NEÜBAP16/2F12)

Some Physical-Chemical Characteristics and Irrigation Water Quality Classes of the Dams in Edirne Province

Tüm Dünya’nın güncel sorunu olan su kirliliği Trakya Bölgesinde de sanayileşme, kentleşme ve nüfusartışıyla paralel olarak artmış ve hızla artmaya devam etmektedir. Aynı zamanda yoğun ve denetimsizsu tüketimi Trakya Bölgesindeki yer altı ve yer üstü su kaynaklarının günden güne azalmasına nedenolmaktadır. Sulamada kullanılan suların kalitesinin bilinmesi, bitki yetiştiriciliği ve ileriye dönük topraktaoluşabilecek problemlerin önüne geçilebilmesi için önemli bir göstergedir. Bu çalışmada, Edirne ilinde,işletmedeki 4 adet baraj ele alınmış ve sulama suyu açısından uygunluğu belirlenmiştir. Elde edilensonuçlara göre; Süloğlu barajı T1 A1 ve T2A1, Altınyazı barajı T2A1, Sultanköy barajı T2A1ve Hamzaderebarajı T3A1 sulama suyu sınıfında yer almıştır. Kıtaiçi yerüstü su kaynaklarının sınıflarına göre barajlarınkalite kriterleri irdelendiğinde, Süloğlu, Sultanköy ve Hamzadere barajları II ve III sınıfta, Altınyazı barajı II.sınıfta yer almıştır. FAO-29 sınıflamasına göre, Süloğlu, Sultanköy ve Altınyazı barajları genelde I. sınıftayer alırken, Hamzadere barajı birçok parametre açısından II. sınıfta yer almıştır.Water pollution which is the daily problem of the whole world has increased in parallel with industrialization, urbanization and population, and it is increasing rapidly. At the same time, intensive and uncontrolled water consumption causes the decline of underground and over ground water resources day by day in Thrace Region. Having information about the quality of the water used in the irrigation is a significant indicator in order to prevent the problems in the soil. In this study, 4 dams in Edirne province were handled and convenience of the dams in terms of irrigation water was determined. According to the results, Süloğlu dam was in T1A1 and T2A1 irrigation water class. Altınyazı dam, Sultanköy dam and Hamzadere dam were in T3A1 irrigation water class. When the quality criteria of the dams were examined according to the intra-continental ground water sources classes, it was determined that Süloğlu dam, Sultanköy dam and Hamzadere dam were in II and III classes and Altınyazı dam was in the II class. According to FAO-29 classification, Süloğlu, Sultanköy and Altınyazı dams were generally in I the class and Hamzadere dam was in the II class in terms of many parameters

A case report of a rare nonsense ZP1 variant in a patient with oocyte maturation defect

Introduction: Oocyte maturation defect (OOMD) is a rare condition causing female infertility that can be diagnosed during assisted reproduction techniques (ART). OOMD related genes are ZP1, ZP2, ZP3, PANX1, PATL2, TUBB8, WEE2 (OMIM, 2020). We report a case of a 31-year-old woman who had four ART failures diagnosed as empty follicle syndrome and OOMD. She has short stature (-3 SD), bilateral limited extension-exion on elbows. Materials and Methods: Chromosome analysis and uorescence in-situ hybridization (FISH) using X chromosome centromeric and SHOX-probe on interphase nuclei of lymphocytes and mucosal cells was investigated. Whole-exome sequencing (WES) performed via the Illumina platform. Conrmation and familial segregation analysis were performed by Sanger sequencing. Results: Karyotyping and FISH resulted in normal, possible mosaicism was excluded. WES analysis revealed a known, rare, pathogenic homozygous variant in exon 3 (c.628C&gt;T; p.Q210*) of ZP1 gene, and her parents being rst degree cousins were carriers for this variant. Conclusions: ZP1 with autosomal recessive inheritance is related to OOMD-1 (MIM_615774). Zona pellucida (ZP) is a glycoprotein structure surrounding oocytes and is essential for oocyte development. ZP contains four types of receptor proteins (ZP1-4). Our variant in ZP1 is nonsense, premature stop codon causes to truncate ZP1 receptor proteins. This is the rst homozygous occurrence of this variant associated with OOMD. WES ndings were also analyzed for known genes related to short stature and no pathogenic variant has been observed. WES is a valuable method to identify the genetic origin in complex, multigenic conditions like in infertility.Istanbul University ProjectNumber:TSA-2018-3213

A case report of a rare nonsense ZP1 variant in a patient with oocyte maturation defect

Introduction: Oocyte maturation defect (OOMD) is a rare condition causing female infertility that can be diagnosed during assisted reproduction techniques (ART). OOMD related genes are ZP1, ZP2, ZP3, PANX1, PATL2, TUBB8, WEE2 (OMIM, 2020). We report a case of a 31-year-old woman who had four ART failures diagnosed as empty follicle syndrome and OOMD. She has short stature (-3 SD), bilateral limited extension-exion on elbows. Materials and Methods: Chromosome analysis and uorescence in-situ hybridization (FISH) using X chromosome centromeric and SHOX-probe on interphase nuclei of lymphocytes and mucosal cells was investigated. Whole-exome sequencing (WES) performed via the Illumina platform. Conrmation and familial segregation analysis were performed by Sanger sequencing. Results: Karyotyping and FISH resulted in normal, possible mosaicism was excluded. WES analysis revealed a known, rare, pathogenic homozygous variant in exon 3 (c.628C&gt;T; p.Q210*) of ZP1 gene, and her parents being rst degree cousins were carriers for this variant. Conclusions: ZP1 with autosomal recessive inheritance is related to OOMD-1 (MIM_615774). Zona pellucida (ZP) is a glycoprotein structure surrounding oocytes and is essential for oocyte development. ZP contains four types of receptor proteins (ZP1-4). Our variant in ZP1 is nonsense, premature stop codon causes to truncate ZP1 receptor proteins. This is the rst homozygous occurrence of this variant associated with OOMD. WES ndings were also analyzed for known genes related to short stature and no pathogenic variant has been observed. WES is a valuable method to identify the genetic origin in complex, multigenic conditions like in infertility.Istanbul University ProjectNumber:TSA-2018-3213

Our experience of spinal dural arteriovenous fistula: 4 case reports

Spinal dural arteriovenous fistula, which is caused by the low flow shunts between dural arteries and the perimedullary venous system shows progressive myelopathy signs. It is usually found in the thoracic region. It is vital to accurately make differential diagnosis since the disease may cause irreversible injury. In this case report we aimed to discuss four cases of spinal arteriovenous fistula that showed different outcomes

Molecular identification of viral agents associated with acute conjunctivitis: a prospective controlled study

Background: Viral conjunctivitis are the most frequent infections in ophthalmology clinics. The diagnosis is usually relying on clinical findings and medical history. However, topical antibiotics are often used unnecessarily addition to symptomatic treatment because of unsure agents. We aimed to detect the Adenovirus, Coxsackievirus and Enterovirus from conjunctiva and pharyngeal samples of patients. Methods: The conjunctiva and pharyngeal samples of the patients with conjunctivitis were taken by Virocult transport media and kept at −80 ̊C up to study day. Adenovirus spp, Enterovirus 70 and Enterovirus 71, Coxsackie A24 and Coxsackie A16 were detected by real-time PCR. Samples from healthy health care workers of ophthalmology clinic were used for control group. Results: A total of 176 samples (conjunctival and pharyngeal samples of 62 patient and 26 healthy subjects) were included. The mean age of 34 (55.7%) male and 27 (44.3%) female patients was 34 ± 17. Twenty five (40.3%) of the patients were receiving antibiotic drops at first visit. The main etiologic agent in conjunctival samples was found to be Adenovirus (46/62, 74.2%) followed by Enterovirus 70 (4/62, 6.4%) and Enterovirus 71 (4/62, 6.4%). Coxsackievirus 16 and 24 were also found in 2 patients (1/62 each, 1.6%). Pharyngeal samples were also positive for Adenovirus (20/62, 32.3%), Enterovirus 70 and 71 (7/62, 11.3% and 5/62, 8.1% respectively), Coxsackievirus 16 and 24 (2/62, 3.2% and 1/61, 1.6%). Conclusions: It is very difficult in viral conjunctivitis to make clinical differentiation caused by different agents because of common clinical signs and symptoms. In routine clinical work, the viral conjunctivitis usually related with Adenovirus. But almost one fourth of the patients’ conjunctivitis were not related to Adenovirus, which shows the importance of the laboratory diagnostics. True diagnosis plays an important role on prevention of contamination and unnecessary use of antibiotics in viral conjunctivitis. Keywords: Adenovirus, Conjunctivitis, Viral, PC