Crossability of miniature rose and quantitative and qualitative traits in hybrids

Potted miniature roses are popular indoor ornamental plants. Due to consumer demands, different varieties are introduced to the market every year. The most widely used method for the development of potted miniatures is cross breeding. Six divergent popular pot miniature roses as female parents and Rosa centifolia and Black Baccara as male parents as well as 190 of their F1 hybrids were studied to determine the extent of crossability and the heterosis effects for several quantitative and qualitative traits for determining miniature rose breeding potential. The percentage of pollen viability and the pollen germination rate differed between 48.61% and 61.27% and between 23.26% and 32.19%, respectively. All cultivars exhibited a strong correlation between the fruit set, the weight of fruit, the total set, the weight of seed, the number of seeds per fruit, and the seed germination rate. The cultivar Rosa White Star as a female parent exhibited a good fruit set and crossing success, whereas Juanita Kordana showed a poor crossing success rate. The maximum setting after the crossing was that of Rosa White Star × R. centifolia comprising 75% of fruits, 132 total seeds, and seed weight of 0.68 g. The highest number of seeds per fruit (12.63) was obtained from Rosa Bling Love Star × R. centifolia, and the Red Romance × Black Baccara had the maximum germination of seed rate (48%). The potential for heterobeltiosis and heterosis varied and exhibited a contrasting performance for various qualitative and quantitative traits between F1 progenies. The parents and F1 hybrids were sorted into three major groups by cluster analysis based on the phenotypic variation

The Role of Media Literacy in Online Information Searching Strategies

Along with the spread of Web 2.0 technologies, individuals' habits such as learning, socializing, and getting information have changed rapidly. A lot of information, the accuracy of which cannot be trusted, is available in the web, and it becomes difficult to choose useful, relevant, and accurate information. This pollution is also present in the media. The abilities to choose messages in the media, to look at these messages critically, and to produce your own messages are considered among the 21st-century skills. These reasons bring media literacy (ML) and online information searching strategies (OISS) to the agenda. The processes of ML and OISS have interrelated features. Therefore, it is important and necessary to examine these concepts together. Based on this necessity, the aim of the study was to determine the role of ML in OISS. To this end, the data were collected from 1809 pre-service teachers using the OISS inventory and the ML level determination scale. Data were analyzed by descriptive statistics, MANOVA, and multiple regression analysis. According to the results, pre-service teachers' ML and OISS levels were above the moderate level. ML and OISS vary significantly according to the type of websites. In conclusion, ML was revealed as a predictor variable that could explain OISS at a rate of 33.2%

Examining The Effect of School Principals' Democratic Attitudes On Teachers' Perceptions of Organizational Alineation

This study examined the effect of school principals' democratic attitudes on teachers' perceptions of organizational alienation. The survey method was used in the research, and the study population consisted of 7455 teachers working in Sakarya province. In comparison, the sample selected based on a simple random sampling technique consisted of 410 teachers. It was found that participant teachers perceived school principals' democratic attitudes as moderate level. Furthermore, teachers' perceptions of school principals' democratic attitudes and organizational alienation did not differ statistically regarding their gender and professional experience. In contrast, their perceptions differed in terms of school level. At the end of the research, it was reached that teachers' perceptions of organizational alienation correlated statistically positively with school principals' democratic attitudes. School principals' democratic attitudes could explain 9% of the variance in teachers' perceptions of organizational alienation. In light of these findings, school principals should create environments where teachers can express themselves freely and use horizontal and vertical communication channels effectively. Further, teachers should take part in professional team projects with school principals, where they can be involved in decision-making processes to increase their perceptions of school principals’ democratic attitudes. Based on all findings obtained in the study, school principals should create environments where teachers can express themselves freely and use both horizontal and vertical communication channels effectively. Further, teachers should take part in professional team projects with school principals, where they can be involved in decision-making processes to increase their perceptions of school principals' democratic attitudes

The Examination of Online Information Searching Strategies of Students That Use Social Network

Bu çalışmanın amacı, sosyal ağ kullanan öğrencilerin çevrimiçi bilgi arama stratejilerini, eğitim düzeyi, yaş ve günlük internet kullanım süresi açısından incelemektir. İlişkisel tarama modelinde desenlenen araştırmanın örneklemini çevrimiçi bir sosyal ağ uygulaması aracılığıyla ulaşılan 1135 katılımcı oluşturmaktadır. Araştırma verileri Demografik Özellikleri Belirleme Formu ve Çevrimiçi Bilgi Arama Stratejileri Envanteri ile toplanmıştır. Verilerin çözümlenmesinde betimsel istatistikler ve tek faktörlü varyans analizi tekniklerinden yararlanılmıştır. Araştırmanın bulgularına göre sosyal ağ kullanan öğrencilerin çevrimiçi bilgi arama stratejileri, yaş, eğitim düzeyi ve günlük internet kullanım süresi bakımından anlamlı farklılık göstermektedir. Bu anlamlı farklılığın daha net belirlenmesi ve bütüncül bir bakış açısının ortaya konması için gelecek araştırmalarda farklı sosyal ağ platformu kullanan bireyler ile birlikte sosyal ağ kullanmayan bireyler de sürece katılarak veri toplanması ve çok değişkenli istatistiksel yöntemlerden yararlanılması önerilmektedir.The purpose of this study is to determine the online information searching strategies of students that use social network by the educational level, age and daily internet use. The sample of the study designed as a relational model constitute 1135 participant achieved through the social networking application. The research data were collected with the Demographic Characteristics Form and the Online Information Searching Strategy Inventory. In data analysis, descriptive statistics and one way Anova were used. According to findings, online information searching strategies of students that use social network had significant difference in terms of educational level, age and daily internet use. Future researches are recommended with various social networking platform users and nonusers and utilization of multivariate statisticals methods to clarify this significant difference and reveal holistic perspective

Çocuk Hastalarda Avulsiyon Nedeniyle Kaybedilmiş Anterior Dişler Yerine Uygulanan Farklı Tedavi Yaklaşımları: 3 OLGU SUNUMU

Avulsiyon sık görülen görülen ciddi bir yaralanma tipidir. Avulse dişler uzun dönem takibi sonucu kaybedilebilir veya replantasyon gerçekleşmeyebilir. Bu durum avülse dişlerin yerine çocuklarda büyüme ve gelişmeyi olumsuz etkilemeyecek şekilde çeşitli tedaviler uygulamayı gerektirmektedir. Bu vaka raporunda üst kesici dişlerini avulsiyon sonrası kaybetmiş 3 farklı hastaya uygulanan tedavi yaklaşımları sunulmuştur. İlk olguda kaza yerinde dişleri kaybolmuş hastaya diş ilaveli hareketli yer tutucu yapılmıştır. Fakat işbirliği sağlanamamış, sabit yer tutucuya geçilmesine karar verilmiştir. İkinci olguda avulse dişiyle kliniğe başvurmuş hastanın dişi replante edilmiştir. 2 yıllık takip sonucu eksternal rezorpsiyon gözlenen dişin çekimi gerçekleşmiş ve yerine fiberle güçlendirilmiş adeziv köprü uygulaması yapılmıştır. Üçüncü olguda avulse 12 numaralı dişi replante edilememiş 10 yaşındaki erkek hastaya diş ilaveli hareketli yer tutucu yapılmıştır. Bu hastaların farklı tedavi yaklaşımlarıyla estetik , fonetik ,gelişimsel ihtiyaçları karşılanmıştır

Pilot Ölçekli Fotofermentatif Hidrojen Üretimi için bir Reaktör Sisteminin Tasarımı, Kurulumu, İşletilmesi ve Analizi

TÜBİTAK MAG Proje01.11.2016Hidrojen, sürdürülebilir yöntemlerle üretildiği takdirde tükenen fosil yakıtların yerini alabilecek potansiyele sahiptir. Fotosentetik bakteriler, ışık altında organik besiyerlerinden hidrojen üretebilmektedir. Küçük ölçeklerde (1 litre veya daha az hacimli) iyi tanımlanmış bu biyolojik üretimin, ‘pilot ölçek’ tabir edilen 10 litre ve üzeri sistemlerde, ucuz besiyerleriyle ve doğal güneş ışığıyla, açık ortamda gerçekleştirilebilmesi, büyük ölçeklerde üretimi değerlendirmek için önemli bir adımdır. Bu projede, bir şeker yan ürünü olan melastan tek aşamalı bir sistemle açık havada ve 9-20 litre sıvı hacimli fotobiyoreaktör sistemlerinde hidrojen üretimi planlanmış, gerçekleştirilmiş ve incelenmiştir. İlk aşamada, pilot-ölçekli, modüler bir fotobiyoreaktör, akış ve ışık dağılımı, sıvı-gaz sızdırmazlığı, kapladığı yüzey alanı ve soğutma entegrasyonu gibi çok sayıda kriter göz önünde bulunarak tasarlanmıştır. Tasarımın akış dağılımı simüle edilmiş, sonuçlar doğrultusunda tüplerin iç çap ve uzunluğu gibi parametreler belirlenmiş ve 9-20 litre hacimli cam fotobiyoreaktörler yerli imkanlarla imal edilmiştir. İkinci aşamada, fotobiyoreaktörlerin açık havada üzerine etki eden ısı unsurları modellenerek mertebe olarak hesaplanmış ve buna bağlı soğutma görevi belirlenmiştir. Temel bulgular, radyasyon öğelerinin belirleyici unsurlar olduğunu göstermektedir. Bu bulgular ışığında bir sıcaklık kontrol sistemi tasarlanmış, üretilmiş ve fotobiyoreaktöre entegre edilmiştir. Şeker kullanımına yönelik küçük-ölçekli deneylerde, 5 mM sükroz içerecek şekilde seyreltilen melasta en yüksek hidrojen üretimi elde edilmiş, pilot-ölçekli deneyler de buna göre tasarlanmıştır. Pilot-ölçekli fotobiyoreaktörler, 2015 ve 2016 yaz aylarında iki kez çalıştırılmış, ilk denemede 9-11 litrelik iki fotobiyoreaktör, ikincisinde ise 20 litrelik tek bir fotobiyoreaktör işletilmiştir. Sıvı ortam sıcaklığı kontrol sistemiyle sabit tutulmuştur. Melasla çalıştırılan iki fotobiyoreaktörde de 0.52 mol/m3saat'e varan ve küçük-ölçekli deney değerlerine yakın hızlarda hidrojen üretimi gözlenmiştir. Deneylerde pH değeri tekrarlanabilir bir şekilde düşmekte ve optimum koşullardan uzaklaşmaya sebep olduğu için hidrojen üretimini olumsuz etkilemektedir. Son olarak, teknik olarak yapılabildiği gösterilen pilot-ölçekli üretimin ekonomik uygulanabilirliğine yönelik bir analiz gerçekleştirilmiştir. Yapılan analizde, ekonomik uygulanabilirliğin olması için bakteri bazında üretkenliğin yükseltilmesi gerektiği anlaşılmıştır. Üretkenliği artırmaya yönelik öneriler raporda belirtilmiştir

Relationship of Serum Trimethylamine N-Oxide Levels With Carotid Intima-Media Thickness and Disease Activity in Psoriasis Patients

Introduction:  Psoriasis is an inflammatory disease that can cause cardiovascular comorbidities. Some recent studies have indicated that impaired gut microbiota and metabolites may be associated with inflammatory diseases. Objectives: In this study, the relationship between serum trimethylamine n-oxide (TMAO, a gut bacterial metabolite) level and carotid intima-media thickness (CIMT) and disease severity in psoriasis patients was investigated. Methods: Age- and gender-matched 73 patients and 72 healthy controls were included in the study. In both groups serum trimethylamine n-oxide(TMAO), oxidized low- density lipoprotein (ox-LDL), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglyceride, total cholesterol, high-sensitivity C-reactive protein (hs-CRP), creatinine, aspartate aminotransferase (AST) and alanine aminotransferase(ALT) levels were recorded and the carotid intima-media thickness (CIMT) was measured by B-mode ultrasonography by a cardiologist.   Results: TMAO, hs-CRP, oxidized-LDL, triglyceride and CIMT levels were statistically higher in the patient group. HDL levels were statistically higher in the control group. There was no significant difference between the two groups in terms of total cholesterol and LDL-C levels. In partial correlation analyzes in the patient group, positive correlations were observed between TMAO and CIMT, LDL-C and total cholesterol levels. Linear regression analysis showed that TMAO levels positively predicted CIMT levels. Conclusions: This study confirmed that psoriasis is a risk factor for the development of cardiovascular disease and that elevated serum TMAO levels in these patients indicate the presence of intestinal dysbiosis. Furthermore, TMAO levels were found to be a predictor of the risk of developing cardiovascular disease in psoriasis patients

Evaluation of the efficacy, safety, and side effects of secukinumab in patients with moderate-to-severe psoriasis: Real-world data from a retrospective multicenter study

Background: Clinical studies have demonstrated that IL-17A inhibition with secukinumab is effective for clearing the skin of patients with psoriasis and has a favorable safety profile. Objective: The authors aim to determine whether secukinumab is effective and safe for the treatment of moderate-to-severe chronic psoriasis based on clinical experience with this drug. Method: The authors conducted a multicenter retrospective study in nine referral centers and included patients with psoriasis who had received secukinumab between March 2018 to November 2020. Data on demographic characteristics, Psoriasis Area and Severity Index (PASI) scores, and previous treatments were collected from medical records. Patients were evaluated at 12, 24, and 52 weeks with respect to response to treatment and side effects. Results: In total, 229 patients were recruited for the study. A PASI score improvement of ≥90 points over the baseline was achieved by 79%, 69.8%, and 49.3% of patients at weeks 12, 24, and 52, respectively. The most common adverse events wereCandida infections and fatigue. In total, 74 (32%) patients discontinued treatment by week 52, including due to adverse events, or secondary ineffectiveness. Study limitations: Retrospective design. Conclusions: These findings suggest that secukinumab therapy is reasonably effective in patients with moderate-to-severe psoriasis. Comorbidities and time length of the disease can affect the response to treatment. The rates of adverse events were high in this patient population

Evaluation of Vascular Involvement in Children with Celiac Disease

Aim:Celiac disease is associated with an increased risk of cardiovascular disease due to inflammation and autoimmunity involved in its pathophysiology. We aimed to evaluate vascular involvement in children with celiac disease based on their augmentation index, carotid pulse wave velocity, carotid intima-media thickness, echocardiographic findings, and blood pressure.Materials and Methods:This cross-sectional and controlled study was performed at a single center between 2018 and 2019. The study population consisted of 44 patients with celiac disease who had been on a gluten-free diet for at least one year.Results:We compared celiac patients with a healthy group. While the celiac patients had significantly higher carotid intima media thickness and carotid pulse wave velocity values, there was no difference in the augmentation index values. There was no significant difference in carotid artery intimal medial thickness, augmentation index and carotid pulse wave velocity values between the diet-compliant and non-compliant groups.Conclusion:Although hypertension was not detected, arterial stiffness and carotid intima media thickness measurements were higher in the celiac disease patients compared to the healthy controls. This showed that these parameters can be used in early vascular damage assessment. These measurements, which are non-invasive and repeatable, can be a guide for the monitoring of the development of preclinical atherosclerosis in the follow-up of the pediatric patients diagnosed with celiac disease