Vernacular housing practices in Burkina Faso: Representative models of construction in Ouagadougou and walls hygrothermal efficiency

peer reviewedIn Burkina Faso, particularly in Ouagadougou, the walls of the houses are made of several local materials. The choice of a material implies a suitable constructive technique and an appropriate architecture. The walls are either earth-based, i.e. Compressed Earth Blocks (CEBs) or Adobe, or based on cement-based materials such as hollow concrete blocks. This paper proposes a description of the vernacular construction practices according to the material used for the walls and tries to explore the hygrothermal behaviour of various wall compositions. A hygrothermal simulation of a hollow concrete blocks wall and a CEBs wall using the WUFI®Pro software is carried out in order to compare the humidity flux passing through interior surface of each wall and to analyze the influence of integrated moisture in the calculation of heat flow. It is shown that, for CEBs wall, both thermal and hygrothermal simulation of heat flow give similar results. © 2017 The Authors. Published by Elsevier Ltd

Body mass index and disease activity in chronic inflammatory rheumatic diseases: results of the Cardiovascular in Rheumatology (Carma) Project

Objective: Since obesity has been associated with a higher inflammatory burden and worse response to therapy in patients with chronic inflammatory rheumatic diseases (CIRD), we aimed to confirm the potential association between body mass index (BMI) and disease activity in a large series of patients with CIRDs included in the Spanish CARdiovascular in rheuMAtology (CARMA) registry. Methods: Baseline data analysis of patients included from the CARMA project, a 10-year prospective study of patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA) attending outpatient rheumatology clinics from 67 Spanish hospitals. Obesity was defined when BMI (kg/m2) was >30 according to the WHO criteria. Scores used to evaluate disease activity were Disease Activity Score of 28 joints (DAS28) in RA, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in AS, and modified DAS for PsA. Results: Data from 2234 patients (775 RA, 738 AS, and 721 PsA) were assessed. The mean ± SD BMI at the baseline visit were: 26.9 ± 4.8 in RA, 27.4 ± 4.4 in AS, and 28.2 ± 4.7 in PsA. A positive association between BMI and disease activity in patients with RA (β = 0.029; 95%CI (0.01- 0.05); p = 0.007) and PsA (β = 0.036; 95%CI (0.015-0.058); p = 0.001) but not in those with AS (β = 0.001; 95%CI (-0.03-0.03); p = 0.926) was found. Disease activity was associated with female sex and rheumatoid factor in RA and with Psoriasis Area Severity Index and enthesitis in PsA. Conclusions: BMI is associated with disease activity in RA and PsA, but not in AS. Given that obesity is a potentially modifiable factor, adequate control of body weight can improve the outcome of patients with CIRD and, therefore, weight control should be included in the management strategy of these patients

X-ray Cluster Cosmology

Sensitive, wide-area X-ray surveys which would be possible with the WFXT will detect huge samples of virialized objects spanning the mass range from sub-groups to the most massive clusters, and extending in redshift to beyond z=2. These samples will be an excellent dataset for carrying out many traditional cosmological tests using the cluster mass function and power spectrum. Uniquely, WFXT will be able not only to detect clusters but also to make detailed X-ray measurements for a large number of clusters and groups right from the survey data. Very high quality measurements of the cluster mass function and spatial correlation over a very wide range of masses, spatial scales, and redshifts, will be useful for expanding the cosmological discovery space, and in particular, in searching for departures from the "concordant" Lambda-CDM cosmological model. Finding such departures would have far-reaching implications on our understanding of the fundamental physics which governs the Universe.Comment: ASTRO2010 decadal survey science white pape

Body mass index and disease activity in chronic inflammatory rheumatic diseases: results of the cardiovascular in rheumatology (Carma) project

Objective: Since obesity has been associated with a higher inflammatory burden and worse response to therapy in patients with chronic inflammatory rheumatic diseases (CIRD), we aimed to confirm the potential association between body mass index (BMI) and disease activity in a large series of patients with CIRDs included in the Spanish CARdiovascular in rheuMAtology (CARMA) registry. Methods: Baseline data analysis of patients included from the CARMA project, a 10-year prospective study of patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA) attending outpatient rheumatology clinics from 67 Spanish hospitals. Obesity was defined when BMI (kg/m2) was >30 according to the WHO criteria. Scores used to evaluate disease activity were Disease Activity Score of 28 joints (DAS28) in RA, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in AS, and modified DAS for PsA. Results: Data from 2234 patients (775 RA, 738 AS, and 721 PsA) were assessed. The mean ± SD BMI at the baseline visit were: 26.9 ± 4.8 in RA, 27.4 ± 4.4 in AS, and 28.2 ± 4.7 in PsA. A positive association between BMI and disease activity in patients with RA (β = 0.029; 95%CI (0.01- 0.05); p = 0.007) and PsA (β = 0.036; 95%CI (0.015-0.058); p = 0.001) but not in those with AS (β = 0.001; 95%CI (-0.03-0.03); p = 0.926) was found. Disease activity was associated with female sex and rheumatoid factor in RA and with Psoriasis Area Severity Index and enthesitis in PsA. Conclusions: BMI is associated with disease activity in RA and PsA, but not in AS. Given that obesity is a potentially modifiable factor, adequate control of body weight can improve the outcome of patients with CIRD and, therefore, weight control should be included in the management strategy of these patients