Prospects and Possibilities

After a long wait, we have the Trusts and Succession (Scotland) Bill to mull over. The proposed legislation will repeal the centenarian Trusts (Scotland) Act 1921 and replace many other provisions relating to trusts and succession. The Bill is largely the product of the Scottish Law Commission’s extensive work in this area, beginning in 2003. This article will evaluate some of the most significant changes and updates to Scots trusts law proposed in the Bill. It will also discuss additional or alternative powers and provisions which have been proposed during the Delegated Powers and Law Reform Committee’s Consultation period, in particular an express power for trustees to consider environmental, social and governance (“ESG”) aims in furtherance of the trust purposes, when making investment decisions

The geology, sedimentology, geochronology and palaeo-environmental reconstruction of the Heelbo hillslope deposit, Free State Province, South Africa

Thesis submitted in fulfillment of the requirements for the Degree of Doctor of Philosophy University of the Witwatersrand South Africa 2015A multidisciplinary sedimentological, stratigraphic, mineralogical and geochronological analysis of a small, fossil-bearing, Holocene hillslope deposit, flanking a mesa, has enabled a reconstruction of the palaeo-environmental history of the region. The hillslope deposit, located on the farm Heelbo in the eastern Free State Povince, South Africa, overlies Jurassic mudrock and sandstone of the Elliot Formation, Karoo Supergroup. The deposit is located on a steep (~10°) slope and covers an area of ~7 km2 in two separate sections. It extends ~475 m downslope and reaches a maximum thickness of at least 6-8 m towards the base. Mineralogy indicates the deposit is sourced from the mesa but its fine grain size and location on a steep slope position Heelbo outside the scope of traditionally described alluvial fans or colluvial deposits. The hillslope deposit is described as an alluvial slope based on the morphology of the deposit and the grain size distribution against the slope gradient. The deposit comprises fine-sand to silt- grain size, but is found on a steep (~10°) slope. The source of the sediment is shown to be the sediment of the mesa, rather than input from an aeolian source. The grains are described as sub-angular and poorly sorted which also suggests a local provenance for the sediment. Microscopic and XRF analysis confirm the derivation of the sediment from the Elliot Formation, with the lithic fragments derived from subarkoses to arkoses of the underlying bedrock of the Upper Elliot Formation (UEF) in the Karoo Supergroup. Secondary calcite was visible in only two of the thin sections, thus it is likely due to a diagenetic overprint that is constrained by depth from the surface or time and not to specific layers. The deposit is cut by several mature and continuous gully networks with V-shaped profiles in the proximal slope, and combined V- and U-shaped profiles in the medial and distal sections. Gully formation is linked to both the sodium adsorption ratio (SARs), and high soil clay content, which facilitates swelling and shrinking. The Heelbo deposit comprises two palaeosols (BT1 and BT2) and four sediment (B1, B2, RB and TS) horizons. Through luminescence dating, the ages were found to be approximately 6390 ± 740 years BP for the oldest Brown (B1) horizon and 250 ± 170 years BP for the Red Brown (RB) horizon. The radiocarbon ages of the sediment were inconclusive, but the 14C ages of the fossil bones were in agreement with the luminescence ages. The multiple palaeosol horizons identified suggest two cycles of deposition, pedogenesis and erosion of the alluvial succession. The palaeosols and the presence of calcareous nodules and rhizocretions, and smectite and mixed-layer clay minerals, together with the total absence of illite and kaolinite, suggest protracted, dry periods with intermittent short periods of high rainfall. This is a similar climate regime to what the region experiences currently. Main findings: The Heelbo alluvial slope comprises locally derived sediment, rather than an aeolian source. Heelbo suggests that the hillslope deposits classification system needs to be re-evaluated and opens opportunities for wider study of Pleistocene-Holocene hillslope deposits in central / northern South Africa. This study also contributes to climate change debates in the Holocene

The geology, sedimentology, geochronology and palaeo-environmental reconstruction of the Heelbo hillslope deposit, Free State Province, South Africa

Thesis submitted in fulfillment of the requirements for the Degree of Doctor of Philosophy University of the Witwatersrand South Africa 2015A multidisciplinary sedimentological, stratigraphic, mineralogical and geochronological analysis of a small, fossil-bearing, Holocene hillslope deposit, flanking a mesa, has enabled a reconstruction of the palaeo-environmental history of the region. The hillslope deposit, located on the farm Heelbo in the eastern Free State Povince, South Africa, overlies Jurassic mudrock and sandstone of the Elliot Formation, Karoo Supergroup. The deposit is located on a steep (~10°) slope and covers an area of ~7 km2 in two separate sections. It extends ~475 m downslope and reaches a maximum thickness of at least 6-8 m towards the base. Mineralogy indicates the deposit is sourced from the mesa but its fine grain size and location on a steep slope position Heelbo outside the scope of traditionally described alluvial fans or colluvial deposits. The hillslope deposit is described as an alluvial slope based on the morphology of the deposit and the grain size distribution against the slope gradient. The deposit comprises fine-sand to silt- grain size, but is found on a steep (~10°) slope. The source of the sediment is shown to be the sediment of the mesa, rather than input from an aeolian source. The grains are described as sub-angular and poorly sorted which also suggests a local provenance for the sediment. Microscopic and XRF analysis confirm the derivation of the sediment from the Elliot Formation, with the lithic fragments derived from subarkoses to arkoses of the underlying bedrock of the Upper Elliot Formation (UEF) in the Karoo Supergroup. Secondary calcite was visible in only two of the thin sections, thus it is likely due to a diagenetic overprint that is constrained by depth from the surface or time and not to specific layers. The deposit is cut by several mature and continuous gully networks with V-shaped profiles in the proximal slope, and combined V- and U-shaped profiles in the medial and distal sections. Gully formation is linked to both the sodium adsorption ratio (SARs), and high soil clay content, which facilitates swelling and shrinking. The Heelbo deposit comprises two palaeosols (BT1 and BT2) and four sediment (B1, B2, RB and TS) horizons. Through luminescence dating, the ages were found to be approximately 6390 ± 740 years BP for the oldest Brown (B1) horizon and 250 ± 170 years BP for the Red Brown (RB) horizon. The radiocarbon ages of the sediment were inconclusive, but the 14C ages of the fossil bones were in agreement with the luminescence ages. The multiple palaeosol horizons identified suggest two cycles of deposition, pedogenesis and erosion of the alluvial succession. The palaeosols and the presence of calcareous nodules and rhizocretions, and smectite and mixed-layer clay minerals, together with the total absence of illite and kaolinite, suggest protracted, dry periods with intermittent short periods of high rainfall. This is a similar climate regime to what the region experiences currently. Main findings: The Heelbo alluvial slope comprises locally derived sediment, rather than an aeolian source. Heelbo suggests that the hillslope deposits classification system needs to be re-evaluated and opens opportunities for wider study of Pleistocene-Holocene hillslope deposits in central / northern South Africa. This study also contributes to climate change debates in the Holocene

Developing the repository manager community

This paper describes activities which have taken place within the UK institutional repository (IR) sector focusing on developing a community of practice through the sharing of experiences and best practice. This includes work done by the UK Council of Research Repositories (UKCoRR) and other bodies, together with informal activities, such as sharing the experience of organising Open Access Week events. The paper also considers future work to be undertaken by UKCoRR to continue developing the community

THE CONTRIBUTION OF LONG-RANGE TRANSPORT OF AIR POLLUTION TO THE SULPHUR BUDGET OF THE UNITED ARAB EMIRATES

Student Number :8701745W - MSc research report - Faculty of ScienceAn air chemistry study over the United Arab Emirates revealed a high concentration of sulphur dioxide. SO2 and its resultant aerosols can have a significant effect on the atmospheric processes. These aerosols could both directly and indirectly affect the climate by scattering solar radiation and increasing the albedo of the atmosphere or by altering the cloud formation processes and characteristics. Sulphur dioxide and the resultant aerosols also have a damaging effect on the environment and on human health. Previous studies reviewed suggest that pollution can be transported for hundreds of kilometres from the source of the emission and affect the air chemistry of the receptor regions. The possibility that long-range transport of pollution to the UAE may have contributed to these high concentrations was also investigated. The possibility that the UAE is a receptor region of pollution transported over long distances is investigated with the intention of identifying the possible source regions of this pollution. In order to examine the import of pollution to the UAE it was important to analyse the background sulphur concentrations of the atmosphere over the UAE

Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis

AbstractThe GTPase dynamin plays an essential role in clathrin-mediated endocytosis [1–3]. Substantial evidence suggests that dynamin oligomerisation around the necks of endocytosing vesicles and subsequent dynamin-catalysed GTP hydrolysis is responsible for membrane fission [4,5]. The pleckstrin homology (PH) domain of dynamin has previously been shown to interact with phosphoinositides, but it has not been determined whether this interaction is essential for dynamin's function in endocytosis [6–9]. In this study, we address the in vivo function of the PH domain of dynamin by assaying the effects of deletions and point mutations in this region on transferrin uptake in COS-7 fibroblasts. Overexpression of a dynamin construct lacking its entire PH domain potently blocked transferrin uptake, as did overexpression of a dynamin construct containing a mutation in the first variable loop of the PH domain. Structural modelling of this latter mutant suggested that the lysine residue at position 535 (Lys535) may be critical in the coordination of phosphoinositides, and indeed, the purified mutant no longer interacted with lipid nanotubes. Interestingly, the inhibitory phenotype of cells expressing this dynamin mutant was partially relieved by a second mutation in the carboxy-terminal proline-rich domain (PRD), one that prevents dynamin from binding to the Src homology 3 (SH3) domain of amphiphysin. These data demonstrate that dynamin's interaction with phosphoinositides through its PH domain is essential for endocytosis. These findings also support our hypothesis that PRD–SH3 domain interactions are important in the recruitment of dynamin to sites of endocytosis

Construction costs, chemical composition and payback time of high- and low-irradiance leaves

The effect of irradiance on leaf construction costs, chemical composition, and on the payback time of leaves was investigated. To enable more generalized conclusions, three different systems were studied: top and the most-shaded leaves of 10 adult tree species in a European mixed forest, top leaves of sub-dominant trees of two evergreen species growing in small gaps or below the canopy in an Amazonian rainforest, and plants of six herbaceous and four woody species grown hydroponically at low or high irradiance in growth cabinets. Daily photon irradiance varied 3-6-fold between low- and high-light leaves. Specific leaf area (SLA) was 30-130% higher at low light. Construction costs, on the other hand, were 1-5% lower for low-irradiance leaves, mainly because low-irradiance leaves had lower concentrations of soluble phenolics. Photosynthetic capacity and respiration, expressed per unit leaf mass, were hardly different for the low- and high-light leaves. Estimates of payback times of the high-irradiance leaves ranged from 2-4 d in the growth cabinets, to 15-20 d for the adult tree species in the European forest. Low-irradiance leaves had payback times that were 2-3 times larger, ranging from 4 d in the growth cabinets to 20-80 d at the most shaded part of the canopy of the mixed forest. In all cases, estimated payback times were less than half the life span of the leaves, suggesting that even at time-integrated irradiances lower than 5% of the total seasonal value, investment in leaves is still fruitful from a carbon-economy point of view. A sensitivity analysis showed that increased SLA of low-irradiance leaves was the main factor constraining payback times. Acclimation in the other five factors determining payback time, namely construction costs, photosynthetic capacity per unit leaf mass, respiration per unit leaf mass, apparent quantum yield, and curvature of the photosynthetic light-response-curve, were unimportant when the observed variation in each factor was examine

Human Tear Fluid Reduces Culturability of Contact Lens-Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence-Associated Type III Secretion System

Purpose The type III secretion system (T3SS) is a significant virulence determinant for Pseudomonas aeruginosa. Using a rodent model, we found that contact lens(CL)-related corneal infections were associated with lens surface biofilms. Here, we studied the impact of human tear fluid on CL-associated biofilm growth and T3SS expression. Methods P. aeruginosa biofilms were formed on contact lenses for up to 7 days with or without human tear fluid, then exposed to tear fluid for 5 or 24 h. Biofilms were imaged using confocal microscopy. Bacterial culturability was quantified by viable counts, and T3SS gene expression measured by RT-qPCR. Controls included trypticase soy broth, PBS and planktonic bacteria. Results With or without tear fluid, biofilms grew to ∼108 CFU viable bacteria by 24 h. Exposing biofilms to tear fluid after they had formed without it on lenses reduced bacterial culturability ∼180-fold (P\u3c.001). CL growth increased T3SS gene expression versus planktonic bacteria [5.46 ± 0.24-fold for T3SS transcriptional activitor exsA (P=.02), and 3.76 ± 0.36-fold for T3SS effector toxin exoS(P=.01)]. Tear fluid further enhanced exsA and exoS expression in CL-grown biofilms, but not planktonic bacteria, by 2.09 ± 0.38-fold (P=.04) and 1.89 ± 0.26-fold (P\u3c.001), respectively. Conclusions Considering the pivitol role of the T3SS in P. aeruginosa infections, its induction in CL-grown P. aeruginosa biofilms by tear fluid might contribute to the pathogenesis of CL-related P. aeruginosa keratitis

DataMoves:Entangling data and movement to support computer science education

In the domain of computing education for children, much work has been done to devise creative and engaging methods of teaching about programming. However, there are many other fundamental aspects of computing that have so far received relatively less attention. This work explores how the topics of number systems and data representation can be taught in a way that piques curiosity and captures learners’ imaginations. Specifically, we present the design of two interactive physical computing artefacts, which we collectively call DataMoves, that enable students, 12-14 years old, to explore number systems and data through embodied movement and dance. Our evaluation of DataMoves, used in tandem with other pedagogical methods, demonstrates that the form of embodied, exploration-based learning adopted has much potential for deepening students’ understandings of computing topics, as well as for shaping positive perceptions of topics that are traditionally considered boring and dull

Pathfinders: Realizing Reconciliation Through Lessons Learned

In 2016, a group of Indigenous and non-Indigenous scholars came together to imagine a better world through a bold approach to education at the Werklund School of Education. This imagining took the form of a newly designed graduate pathway program which focused on meaningfully and actively responding to Canada’s Truth and Reconciliation Commission’s (TRC) (2015) 94 Calls to Action. Central to the design of our program is the inclusion of a capstone service-learning project that asks graduate students to bring together Indigenous and non-Indigenous groups in designing and delivering projects of mutual benefit. In sharing insights from their respective learning journeys, our students reveal the complexities and challenges of reconciliatory work but also its many rewards. Further, in sharing these courageous acts, we hope to inspire others to take action