6 research outputs found
ElaboraciĂłn de fichas, guĂas y videos de procedimientos de ensayos normados para el Manual de laboratorio de hormigones de la USFQ
This document shows a manual for the USFQâs concrete laboratory, for which 10
support guides for the American Society of Testing and Materials (ASTM) were made. These
standards have the C designation, which means that are applied at the time of performing tests
that help, either obtain or calculate important information on a material composed of cement;
both in its fresh and hardened state...El presente documento es el desarrollo de un manual para el laboratorio de hormigĂłn
de la USFQ, para el cual se realizaron guĂas de apoyo para 10 normativas ASTM (American
Society of Testing and Materials), con designaciĂłn C; las mismas que son aplicadas al
momento de realizar ensayos que ayuden a obtener, o calcular, informaciĂłn de importancia
sobre un material compuesto por cemento; tanto en su estado fresco, como endurecido..
MASTREE+: Time-series of plant reproductive effort from six continents.
Significant gaps remain in understanding the response of plant reproduction to environmental change. This is partly because measuring reproduction in long-lived plants requires direct observation over many years and such datasets have rarely been made publicly available. Here we introduce MASTREE+, a data set that collates reproductive time-series data from across the globe and makes these data freely available to the community. MASTREE+ includes 73,828 georeferenced observations of annual reproduction (e.g. seed and fruit counts) in perennial plant populations worldwide. These observations consist of 5971 population-level time-series from 974 species in 66 countries. The mean and median time-series length is 12.4 and 10Â years respectively, and the data set includes 1122 series that extend over at least two decades (â„20Â years of observations). For a subset of well-studied species, MASTREE+ includes extensive replication of time-series across geographical and climatic gradients. Here we describe the open-access data set, available as a.csv file, and we introduce an associated web-based app for data exploration. MASTREE+ will provide the basis for improved understanding of the response of long-lived plant reproduction to environmental change. Additionally, MASTREE+ will enable investigation of the ecology and evolution of reproductive strategies in perennial plants, and the role of plant reproduction as a driver of ecosystem dynamics
Effectiveness of Duloxetine versus Other Therapeutic Modalities in Patients with Diabetic Neuropathic Pain: A Systematic Review and Meta-Analysis
Objectives: Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes mellitus (DM) with symptoms like intense pain and impaired quality of life. This condition has no treatment; instead, the pain is managed with various antidepressants, including duloxetine. The aim of this study is to analyze the evidence on the efficacy of duloxetine in the management of DPN. Methods: A systematic search in different databases was conducted using the keywords âdiabetic neuropathyâ, âduloxetine therapyâ, âneuropathic painâ, and âDiabetes Mellitusâ. Finally, eight studies were included in this meta-analysis. Results: All articles comparing duloxetine at different doses vs. a placebo reported significant differences in favor of duloxetine on pain scales like 24 h Average Pain Severity (standardized mean difference [SMD] = â1.06, confidence interval [CI] = â1.09 to â1.03, and p p p p Conclusions: Duloxetine appears to be effective in the management of DPN in different pain, symptom improvement, and quality of life scales
Colombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery â a prospective cohort studyResearch in context
Summary: Background: Surgical care holds significant importance in healthcare, especially in low and middle-income countries, as at least 50% of the 4.2 million deaths within the initial 30 days following surgery take place in these countries. The Lancet Commission on Global Surgery proposed six indicators to enhance surgical care. In Colombia, studies have been made using secondary data. However, strategies to reduce perioperative mortality have not been implemented. This study aims to describe the fourth indicator, perioperative mortality rate (POMR), with primary data in Colombia. Methods: A multicentre prospective cohort study was conducted across 54 centres (hospitals) in Colombia. Each centre selected a 7-day recruitment period between 05/2022 and 01/2023. Inclusion criteria involved patients over 18 years of age undergoing surgical procedures in operating rooms. Data quality was ensured through a verification guideline and statistical analysis using mixed-effects multilevel modelling with a case mix analysis of mortality by procedure-related, patient-related, and hospital-related conditions. Findings: 3807 patients were included with a median age of 48 (IQR 32â64), 80.3% were classified as ASA I or II, and 27% of the procedures had a low-surgical complexity. Leading procedures were Orthopedics (19.2%) and Gynaecology/Obstetrics (17.7%). According to the ClavienâDindo scale, postoperative complications were distributed in major complications (11.7%, 10.68â12.76) and any complication (31.6%, 30.09â33.07). POMR stood at 1.9% (1.48â2.37), with elective and emergency surgery mortalities at 0.7% (0.40â1.23) and 3% (2.3â3.89) respectively. Interpretation: The POMR was higher than the ratio reported in previous national studies, even when patients had a lowârisk profile and low-complexity procedures. The present research represents significant public health progress with valuable insights for national decision-makers to improve the quality of surgical care. Funding: This work was supported by Universidad del Rosario and FundaciĂłn Cardioinfantil-Instituto de CardiologĂa grant number CTO-057-2021, project-ID IV-FGV017
PolĂticas pĂșblicas
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