LABORATORIO INTEGRAL DE QUÍMICA ORGÁNICA - IQ

GUÍA PEDAGÓGIC

LABORATORIO INTEGRAL DE QUÍMICA ORGÁNICA - QFB

GUÍA DE EVALUACIÓN DEL APRENDIZAJ

Outflows From Evolved Stars: The Rapidly Changing Fingers Of CRL 618

Our ultimate goal is to probe the nature of the collimator of the outflows in the pre-planetary nebula CRL 618. CRL 618 is uniquely suited for this purpose owing to its multiple, bright, and carefully studied finger-shaped outflows east and west of its nucleus. We compare new Hubble Space Telescope images to images in the same filters observed as much as 11 yr ago to uncover large proper motions and surface brightness changes in its multiple finger-shaped outflows. The expansion age of the ensemble of fingers is close to 100 yr. We find strong brightness variations at the fingertips during the past decade. Deep IR images reveal a multiple ring-like structure of the surrounding medium into which the outflows propagate and interact. Tightly constrained three-dimensional hydrodynamic models link the properties of the fingers to their possible formation histories. We incorporate previously published complementary information to discern whether each of the fingers of CRL 618 are the results of steady, collimated outflows or a brief ejection event that launched a set of bullets about a century ago. Finally, we argue on various physical grounds that fingers of CRL 618 are likely to be the result of a spray of clumps ejected at the nucleus of CRL 618 since any mechanism that form a sustained set of unaligned jets is unprecedented.HST GO 11580NASA through Space Telescope Science Institute GO11580NASA NAS5-26555Boeing ScholarshipOffice of Undergraduate Academic Affairs at the University of WashingtonSpanish MICINN CSD2009-00038NASA Office of Space Science NAG5-7584Astronom

“ESTUDIO DE LA INFLUENCIA DE LA CONCENTRACIÓN Y TIEMPO DE REACCIÓN EN PLASTIFICACIÓN Y BIODEGRADACIÓN DE POLIPROPILENO MODIFICADO CON UN ACEITE DE SOYA”

En el presente trabajo se determinaron las condiciones de plastificación de membrana de polipropileno (PP) usando Aceite de Soya Epoxidado y Acrilatado (ASEA), llevando a cabo una reacción de polimerización por injerto, entre el radical libre del carbono trisustituido del PP y el grupo acrilato del ASEA en presencia de luz ultravioleta. Los parámetros a evaluar fueron; el grado de injerto variando la concentración del ASEA y tiempo de reacción en la radiación de luz UV. El método de polimerización por injerto consistió en preparar una solución de ASEA en Dimetilformamida (DMF) a diferentes concentraciones y variando los tiempos de radiación. Se obtuvo un rendimiento de 366 % en peso de injerto a una concentración de 70% y un tiempo de radiación de 6 horas, a estas condiciones se observó el máximo grado de injerto. La membrana fue caracterizada utilizando espectroscopia de infrarrojo con transformada de Fourier (FT-IR-ATR), Difracción de rayos X de polvos, Microscopía Electrónica de Barrido y Ángulo de Contacto.. Para las pruebas de degradación se analizaron diferentes microorganismos tales como Bacillus Cereus, Pseudomonas, Aspergilus Niger y Rhizopus, durante 60 días. Encontrando que el microorganismo Pseudomona spp produce el mayor porcentaje de degradación a una concentración de 70% y 6 h de radiación UV. En el capítulo 1 y 2 se describe las generalidades de los polímeros, los tipos de polimerización que se llevan a cabo, los diferentes iniciadores de la polimerización, se describe las características del polipropileno y sus tipos. Se mencionan las generalidades de las membranas y su clasificación. Se habla de las membranas poliméricas, los métodos de preparación y la modificación de las mismas. El capítulo 3 detalla el tema de los aceites naturales y sus derivados, las reacciones en las que están involucrados, se habla de las generalidades del Aceite de Soya Epoxidado y Acrilatado, su polimerización y utilidades. El tema de la degradación polimérica se ve reflejado en el capítulo 4, se describen las generalidades de los microorganismos y su clasificación, las características de las bacterias Bacilluous cereus y Pseudomonas SPP, los hongos Aspergilu niger y 12 Rhizopus stolonifer, los factores que afectan la biodegradación y sus mecanismos. Mientras que en el capítulo 5 se toma el tema de las técnicas de caracterización para el análisis de las pruebas. Finalmente, en el capítulo 6 y 7 se muestra la metodología, los resultados y análisis arrojados en las pruebas para la determinación de las condiciones de polimerización por injerto de la ASEA en la MPP a diferentes concentraciones en peso y variando los tiempos de radiación UV, y las pruebas preliminares de biodegradación usando los microorganismos Bacilluous cereus y Pseudomonas SPP, los hongos Aspergilu niger y Rhizopus stolonifer; además de las conclusiones a las que se llegó en el presente trabajo

An investigation into the characteristics of the phospholipid transfer protein RdgBβ and the phospholipid biosynthetic enzyme Cds1 in the mammalian heart

The conversion of phosphatidic acid (PA) to cytidine diphosphate-diacylglycerol (CDP-DAG) by CDP-DAG synthase (Cds) is the rate-limiting step for the biosynthesis of the mitochondrial lipid, cardiolipin (CL) and phosphatidylinositol (PI), the precursor for many signalling phosphoinositides. There are two Cds isoforms in mammals, Cds1 and Cds2. During cardiomyocyte growth and development, mitochondrial biogenesis is increased under the control of the transcription factor, PGC-1α which also regulates Cds1 expression. Mitochondria have limited capacity to synthesise their own lipids and are dependent on the endo/sarcoplasmic reticulum for many of their lipids, including PI and PA. RdgBβ (Retinal degeneration B beta) is a phosphatidylinositol transfer protein (PITP), recently found to be enriched in cardiac tissue, able to transfer both PI and PA. This investigation attempts to identify the residues within the PITP domain that are required for PA transfer and it focuses on the characterisation of the expression and distribution of RdgBβ and Cds1 in rat hearts and H9c2 cells which are derived from embryonic rat ventricles. Withdrawal of serum and the addition of retinoic acid induces differentiation of H9c2 cells towards a cardiomyocyte-like phenotype. At the protein level, proliferating H9c2 cells have low RdgBβ expression which increases dramatically following differentiation with retinoic acid. The increase in RdgBβ expression occurred in parallel with an elevation in mitochondrial content. In addition to the cytosol, RdgBβ was also located at membrane fractions, suggesting that RdgBβ may facilitate PI and PA transport between the ER and the mitochondria. The regulation of mRNA expression of Cds1 was not associated with cellular differentiation but with vasopressin stimulation of H9c2 cells. Both myoblasts and differentiated H9c2 cells showed an increase of Cds1 mRNA suggesting that Cds1 is involved in the PI cycle

The influence of the Common Agricultural Policy on agricultural landscapes

Agriculture is both a large‐scale user of land and a provider of landscapes. The adaptation of agricultural practices to local conditions has led to a wide variety of "cultural landscapes" in Europe. The Common Agricultural Policy being a major driver of land use and farming practices change in Europe, it also affects landscapes. The report analyzes how the CAP design and implementation have influenced the agricultural landscapes. It provides a catalogue of CAP measures that have been and are currently influencing landscapes are presented, as well as the expected effects derived from the proposal for the post 2013 CAP. It differentiates between Pillar 1 and Pillar 2, and between measures with a direct focus on landscapes vs. non‐targeted measures which also have the potential to have an influence (positive or negative)). The olive and livestock sectors, where the influence of CAP on landscape is of particular interest, are also analyzed. By providing a list of the potential influences of the CAP on the landscape elements and structures valued by EU citizens, this report provides a knowledge base to support an effective CAP policy design in the direction of improved landscape management, an important component of EU project towards a more sustainable agriculture.JRC.J.4-Agriculture and Life Sciences in the Econom

Propuesta de un diseño de gestión de calidad para la empresa Industrial Ocampo, bajo la NTC 6001 versión 2017, para el año 2020.

Este trabajo será elaborado bajo la dirección de la norma técnica colombiana 6001 gestión en MiPymes, donde se trabajarán diferentes objetivos que aportaran al desarrollo del sistema de gestión de calidad para la empresa Industrial Ocampo SAS, donde se dará a conocer el estado actual de la empresa frente a los requisitos de la norma, abordar el tema por procesos en la organización bajo el ciclo PHVA Planear, Hacer, Verificar y Actuar, y dar a conocer un plan de calidad donde se establezcan responsables, actividades, objetivos y fechas para el desarrollo de premisas identificadas.PregradoADMINISTRADOR(A) DE EMPRESA

Arrestin in ciliary invertebrate photoreceptors : molecular identification and functional analysis in vivo

© The Authors, 2011. This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. The definitive version was published in Journal of Neuroscience 31 (2011): 1811-1819, doi:10.1523/JNEUROSCI.3320-10.2011.Arrestin was identified in ciliary photoreceptors of Pecten irradians, and its role in terminating the light response was established electrophysiologically. Downstream effectors in these unusual visual cells diverge from both microvillar photoreceptors and rods and cones; the finding that key regulatory mechanisms of the early steps of visual excitation are conserved across such distant lineages of photoreceptors underscores that a common blueprint for phototransduction exists across metazoa. Arrestin was detected by Western blot analysis of retinal lysates, and localized in ciliary photoreceptors by immunostaining of whole-eye cryosections and dissociated cells. Two arrestin isoforms were molecularly identified by PCR; these present the canonical N- and C-arrestin domains, and are identical at the nucleotide level over much of their sequence. A high degree of homology to various β-arrestins (up to 70% amino acid identity) was found. In situ hybridization localized the two transcripts within the retina, but failed to reveal finer spatial segregation, possibly because of insufficient differences between the riboprobes. Intracellular dialysis of anti arrestin antibodies into voltage-clamped ciliary photoreceptors produced a gradual slow-down of the photocurrent falling phase, leaving a tail that decayed over many seconds after light termination. The antibodies also caused spectrally neutral flashes to elicit prolonged aftercurrents in the absence of large metarhodopsin accumulation; such aftercurrents could be quenched by chromatic illumination that photoconverts metarhodopsin back to rhodopsin. These observations indicate that the antibodies depleted functionally available arrestin, and implicate this molecule in the deactivation of the photoresponse at the rhodopsin level.This work was supported by National Science Foundation Grant 0639774