120 research outputs found

    Double-sided arc welding with multiple electrodes of vertical joints of steel tanks

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    The increase of the welding productivity is still of immediate interest, which in turn requires the development and implementation of more high-performance welding methods that ensure a consistently high quality of welded joints. One of the ways to further increase the productivity of arc welding processes in the construction of tanks is the industrial use of automatic double-sided arc welding with multiple electrodes in separate weld pools. To establish the relationship between the parameters of the welding mode, energy characteristics, as well as the distance between the torches and their angle of inclination relative to the groove, a physical and mathematical model of the production of the welding joint when four arcs participate in pairs from both sides of the joint has been developed. Thus, computer modeling showed that during weld formation with the movement of the electrode down (vertical down), the possibility of supplying each pair of arcs with pulsed current should be taken into account. During groove filling with the movement of the electrodes up (vertical up), their lateral oscillations and delays at the edges should be carried out according to an aperiodic law in order to minimize the effects of 'magnetic blow'. © Published under licence by IOP Publishing Ltd

    Non-Newtonian Couette-Poiseuille flow of a dilute gas

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    The steady state of a dilute gas enclosed between two infinite parallel plates in relative motion and under the action of a uniform body force parallel to the plates is considered. The Bhatnagar-Gross-Krook model kinetic equation is analytically solved for this Couette-Poiseuille flow to first order in the force and for arbitrary values of the Knudsen number associated with the shear rate. This allows us to investigate the influence of the external force on the non-Newtonian properties of the Couette flow. Moreover, the Couette-Poiseuille flow is analyzed when the shear-rate Knudsen number and the scaled force are of the same order and terms up to second order are retained. In this way, the transition from the bimodal temperature profile characteristic of the pure force-driven Poiseuille flow to the parabolic profile characteristic of the pure Couette flow through several intermediate stages in the Couette-Poiseuille flow are described. A critical comparison with the Navier-Stokes solution of the problem is carried out.Comment: 24 pages, 5 figures; v2: discussion on boundary conditions added; 10 additional references. Published in a special issue of the journal "Kinetic and Related Models" dedicated to the memory of Carlo Cercignan

    Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes

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    We report on single-molecule nanopore sensing combined with position-encoded DNA molecular probes, with chemistry tuned to simultaneously identify various antigen proteins and multiple RNA gene fragments of SARS-CoV-2 with high sensitivity and selectivity. We show that this sensing strategy can directly detect spike (S) and nucleocapsid (N) proteins in unprocessed human saliva. Moreover, our approach enables the identification of RNA fragments from patient samples using nasal/throat swabs, enabling the identification of critical mutations such as D614G, G446S, or Y144del among viral variants. In particular, it can detect and discriminate between SARS-CoV-2 lineages of wild-type B.1.1.7 (Alpha), B.1.617.2 (Delta), and B.1.1.539 (Omicron) within a single measurement without the need for nucleic acid sequencing. The sensing strategy of the molecular probes is easily adaptable to other viral targets and diseases and can be expanded depending on the application required

    Electrochemical Nanoprobes for Single-Cell Analysis

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    The measurement of key molecules in individual cells with minimal disruption to the biological milieu is the next frontier in single-cell analyses. Nanoscale devices are ideal analytical tools because of their small size and their potential for high spatial and temporal resolution recordings. Here, we report the fabrication of disk-shaped carbon nanoelectrodes whose radius can be precisely tuned within the range 5–200 nm. The functionalization of the nanoelectrode with platinum allowed the monitoring of oxygen consumption outside and inside a brain slice. Furthermore, we show that nanoelectrodes of this type can be used to impale individual cells to perform electrochemical measurements within the cell with minimal disruption to cell function. These nanoelectrodes can be fabricated combined with scanning ion conductance microscopy probes, which should allow high resolution electrochemical mapping of species on or in living cells

    Measurements of the νμ\nu_{\mu} and νˉμ\bar{\nu}_{\mu}-induced Coherent Charged Pion Production Cross Sections on 12C^{12}C by the T2K experiment

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    We report an updated measurement of the νμ\nu_{\mu}-induced, and the first measurement of the νˉμ\bar{\nu}_{\mu}-induced coherent charged pion production cross section on 12C^{12}C nuclei in the T2K experiment. This is measured in a restricted region of the final-state phase space for which pμ,π>0.2p_{\mu,\pi} > 0.2 GeV, cos(θμ)>0.8\cos(\theta_{\mu}) > 0.8 and cos(θπ)>0.6\cos(\theta_{\pi}) > 0.6, and at a mean (anti)neutrino energy of 0.85 GeV using the T2K near detector. The measured νμ\nu_{\mu} CC coherent pion production flux-averaged cross section on 12C^{12}C is (2.98±0.37(stat.)±0.31(syst.)+0.490.00(Q2model))×1040 cm2(2.98 \pm 0.37 (stat.) \pm 0.31 (syst.) \substack{ +0.49 \\ -0.00 } \mathrm{ (Q^2\,model)}) \times 10^{-40}~\mathrm{cm}^{2}. The new measurement of the νˉμ\bar{\nu}_{\mu}-induced cross section on 12C^{12}{C} is (3.05±0.71(stat.)±0.39(syst.)+0.740.00(Q2model))×1040 cm2(3.05 \pm 0.71 (stat.) \pm 0.39 (syst.) \substack{ +0.74 \\ -0.00 } \mathrm{(Q^2\,model)}) \times 10^{-40}~\mathrm{cm}^{2}. The results are compatible with both the NEUT 5.4.0 Berger-Sehgal (2009) and GENIE 2.8.0 Rein-Sehgal (2007) model predictions

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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