Effect of essential oils treatment on the frozen storage stability of chub mackerel fillets

The effect of bay leaf (BLO), thyme (TO), rosemary (RO), black seed (BSO), sage (SO), grape seed (GSO), flaxseed (FSO) and lemon (LO) essential oil from vegetable extracted on lipid oxidation and some other quality parameter of frozen chub mackerel during frozen storage at -20A degrees C were examined over a period of 11 months. Taste, odour, texture and overall acceptability of control samples were given 'unacceptable' scores by the sixth month. Based primarily on sensory data, the shelf-lives of frozen chub mackerel were found 6 month for samples treated with oil of TO, RO, BSO, SO and LO and 7 month for samples treated with BLO, GSO and FSO. During the 11-months storing process of chub mackerel, the values of pH, total volatile basic nitrogen (TVB-N), trimethylamine nitrogen (TMA-N) both in control group samples and samples treated with oils did not reach to deterioration levels. Thiobarbituric acid (TBA) and free fatty acid (FFA) values for all treatments remained lower than TBA and FFA values of control samples throughout the 11 month storage period. Particularly, thyme oil treatment is effective in delaying lipid oxidation. Bay leaf, rosemary, sage, lemon, flaxseed and grape seed oils were fallowed

The effect of Lacidipine on Ischemia-Reperfusion Induced oxidative damage in ovaries of female rats.

WOS: 000318217500006In this study, we investigated the effects of lacidipine on XO, MDA, MPO, and GSH levels in ovarian tissues of rats, which are subjected to ischemia and post-ischemic reperfusion. In ovarian ischemia (OI), ovarian ischemia-reperfusion (OIR), 2 mg/kg lacidipine + ovarian ischemia (LOI-2), 4 mg/kg lacidipine + ovarian ischemia (LOI-4), 2 mg/kg lacidipine + ovarian ischemia-reperfusion (LOIR-2), 4 mg/kg lacidipine + ovarian ischemia-reperfusion (LOIR-4) and sham-operated healthy control group (HCG); XO 23.8 +/- 0.94, 13.6 +/- 0.76, 8 +/- 0.57, 5.8 +/- 0.60, 4.5 +/- 0.42, 3.6 +/- 0.55, 2.8 +/- 0.30 u/g, respectively, whereas MDA, 4.8 +/- 0.47, 13.33 +/- 0.66, 3.5 +/- 0.35, 3.4 +/- 0.42, 6.0 +/- 0.57, 5.3 +/- 0.61,2.8 +/- 0.22 mu mol/g protein, respectively. MPO, 6.1 +/- 0.60, 14.1 +/- 0.94, 6.3 +/- 0.66, 6.0 +/- 0.73, 8.8 +/- 0.60, 7.5 +/- 0.76, 6 +/- 1.06 u/g protein, respectively, while GSH 8.0 +/- 0.73, 3.1 +/- 0.47, 8.6 +/- 0.95, 8.9 +/- 0.91, 7.1 +/- 0.60, 7.5 +/- 0.76 ,9.1 +/- 0.47 nmol/g protein, respectively. The present study, conducted on the basis of the mechanism of formation of IR injury, demonstrated that lacidipine prevents ischemia-reperfusion injury in the ovarian tissues

The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide

Cetin, Nihal/0000-0003-3233-8009; Gul, Mehmet Ali/0000-0002-5849-0116;WOS: 000321086300017The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: sham group, ischemia-reperfusion group (IR), nimesulide 25 mg/kg group (NIM 25), and nimesulide 50 mg/kg group (NIM 50). the severe oxidative stress and inflammation that occurred in the ovarian tissue treated I/R were recovered by treatment of nimesulide. the histopathological findings, severe haemorrhage, oedema, vascular congestion accompanied with migration and adhesion of polimorphonuclear leukocytes in the endothelium were observed in the IR group that MDA, MPO and COX-2 levels were found high whereas GSH and COX-1 levels were found low. the severe histopathological findings in IR group were moderate in NIM-25 group whereas those were slight in NIM-50 group. This finding suggests that nimesulide prevents injury due to reperfusion following ischemia better when used with dosage 50 mg/kg

Acrometastasis as first sign of adenocarcinoma of the lung

Lung cancer is a major cause of morbidity and mortality worldwide. Metastasis can be seen in many organs in advanced-stage disease. Acral metastasis rate in cancer is quite low. However, because of the direct opening of the arterial circulation, the risk of acral metastasis stem from lung cancer is higher than any other cancers. Although the mechanism is not known exactly, acral metastases occur in dominant extremities. Here, we present a case with lung adenocarcinoma metastasis of the left hand in the second phalanx. We presented this case which is rarely seen in the literature to emphasize acral metastases