Clinical and Laboratory Characteristics of Hyperprolactinemia in Children and Adolescents: National Survey

Conclusion: We present the largest cohort of children and adolescents with hyperprolactinemia in the literature to date. Hyperprolactinemia is more common in females and cabergoline is highly effective and practical to use in adolescents, due to its biweekly dosing. Indications for surgery in pediatric cases need to be revised

Rapid Acting Insulin Analogue Treatment in Children and Adolescents with Type 1 Diabetes Mellitus; Insulin Glulisine Experience

WOS: 000384166800599

A NEW PREDICTION SYSTEM FOR EVALUATION OF OPTIMAL FINAL HEIGHT IN CHILDREN WITH GROWTH HORMONE DEFICIENCY: IGRO

WOS: 000412595405178

Evaluation of Epicardial AdiposeTissue Thickness in Children Detected Subclinical Hypothyroidism

WOS: 000384166801532

THE ADHERENCE TO GROWTH HORMONE THERAPY IN CHILDREN WITH GROWTH HORMONE DEFICIENCY

WOS: 000412595403207

AN ASSESMENT OF UNEXPECTEDLY HIGH HbA1c LEVEL IN A CASE WITH TYPE 1 DIABETES

WOS: 000382619500017The HbA1c test provides information about blood glucose levels of previous months depending on the erythrocyte lifetime when monitoring diabetic patients. However, various factors such as HbF and other hemoglobin variants can interfere with the measurement of HbA1c. In this study, an unexpectedly high HbA1c level was observed in a patient with type 1 diabetes. In the hemoglobin chain analysis, which explained the reason for the high value, high fetal hemoglobin levels were detected and interfered with HbA1c measurement with the HPLC method. This finding was in concordance with the literature. As a conclusion, it should be considered that hemoglobinopathy might be found in the patients who have higher levels of HbA1c which is not in agreement with the blood glucose. Thus, it can be said that HbA1c test is not a good marker for monitoring such diabetic patients. In such cases, fructosamine or other glycated end products may be a more reliable marker

THE EVALUATION OF PATIENTS RECEIVING GROWTH HORMONE THERAPY

WOS: 000412595402073

Evaluation of Body Composition via Bioelectrical Impedance Analysis in Children with Subclinical Hypothyroidism and Effect of LT4 Treatment; Follow-up Results

KILINC, FATMA/0000-0001-8297-958XWOS: 000384166801535

The effect of subclinical hypothyroidism on body composition parameters in children

WOS:000538622200001PubMed: 32460403Background It's known that overt hypothyroidism increases body fat content and weight. There's limited research about the effect of subclinical hypothyroidism (SH) on body composition in children and the effect of LT4 treatment. We aimed to evaluate body composition parameters in healthy subjects and in children with mild SH (MSH) and determine the effect of LT4 treatment. Methods Sixty-four healthy children and 32 children with MSH were included. Anthropometric measurements and hormonal parameters were evaluated. Body composition was evaluated using bioelectric impedance analysis (BIA). Patients were put on LT4 treatment. BIA was performed again after 12 months of therapy. Results There was no significant difference between the anthropometric parameters and basal metabolic rate of the healthy children and the MSH group. The percentage of trunk muscle mass (TMM) in the MSH group was lower than in the control group (P .05). Conclusions The percentage of TMM in children with MSH was found lower than healthy control group. After LT4 treatment, the percentage of the FFM, TMM and TFFM were increased and the difference between percentage of TMM in children with MSH and healthy controls was insignificant. Our data indicated that MSH might be associated with early changes in body composition parameters

Amylase/creatinine clearance ratio in diabetic ketoacidosis: a case report

WOS: 000345022900035PubMed: 25153214Diabetic ketoacidosis (DKA) accompanies any other intra-abdominal pathology. Serum amylase/lipase levels are commonly used in order to rule out acute pancreatitis in patients having abdominal pain in DKA. A more specific and noninvasive diagnostic tool - amylase/creatinine clearance ratio (ACCR) - can be used to rule out pancreatitis in patients with DKA. A 14-year-old girl was admitted with abdominal pain and nausea. She had been followed up for type 1 diabetes mellitus for the last 5 years. The serum amylase levels were increased up to 687 U/L (normal: 28-120 U/L) on the third day of hospitalization. Simultaneous serum and urinary amylase concentrations were measured, and ACCR was calculated (1.2%). The diagnosis of pancreatitis was ruled out. The serum amylase levels decreased in the following days, and she was discharged. ACCR determination is a simple and specific test to diagnose pancreatitis, especially in patients with DKA