1,035 research outputs found

    Knospe-Betriebe unter der Lupe

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    Die Analyse SMART zeigt auf, wie nachhaltig Knospe-Betriebe sind. Das FiBL hat im Auftrag von Bio Suisse 185 Betriebe analysiert, erste Ergebnisse sind nun ausgewertet

    Fermes Bourgeon sous la loupe

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    L’analyse SMART montre à quel point les fermes Bourgeon sont durables. Le FiBL a analysé 185 fermes sur mandat de Bio Suisse, et les premiers résultats sont maintenant disponibles

    Der Lebensyzklus eines Kleidungsstücks aus Baumwolle

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    Der Lebensyzklus eines Kleidungsstücks aus Baumwolle

    Repräsentative SMART-Nachhaltigkeitsbewertung der Bio Suisse-Betriebe. Kurzbericht 2018

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    Die Knospe gilt als Garant für eine nachhaltige Landwirtschaft. Doch wie nachhaltig wirtschaften die Knospe-Höfe tatsächlich,was läuft gut, wo gibt es Verbesserungspotential? Diesen Fragen gingen das FiBL und die SFS im Auftrag von Bio Suisse auf den Grund. Zum Einsatz kam dabei SMART (Sustainability Monitoring and Assessment RouTine), ein Instrument, welches das FiBL zur ganzheitlichen Nachhaltigkeitsanalyse und Bewertung von landwirtschaftlichen Betrieben und Lebensmittelunternehmen entwickelt hat. Die Bewertung beruht auf einer Betriebsbesichtigung und einem etwa zwei- bis dreistündigen Interview mit den Betriebsleitern zu verschiedenen für die Landwirtschaft relevanten Themenbereichen. Innerhalb von drei Jahren wurden so 185 Höfe auf ihre Nachhaltigkeit hin untersucht. Die Stichprobe wurde so gewählt, dass alle Betriebstypen und Landwirtschaftszonen abgebildet wurden. Zu den Projektzielen gehörten: - Repräsentative Bewertung der Nachhaltigkeitsleistungen der Knospe-Betriebe durch eine externe Institution. - Ermöglichung der kontinuierlichen Entwicklung der Betriebe und Sicherstellung der Zukunftsfähigkeit der Bio Suisse Betriebe sowie der Marke Knospe. - Erarbeitung einer glaubwürdigen Informationsbasis zur Kommunikation der Nachhaltigkeit von Knospe-Betrieben. Die Ergebnisse sollen sowohl für die Verbesserung des Beratungs- und Schulungsangebots im Bereich Nachhaltigkeit als auch für die strategische Weiterentwicklung des Verbands genutzt werden

    Concept for a multi-purpose academic gripper

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    In “concept for a new precise academic gripper” the mechanical aspects of the new gripper were presented [3]. In this paper, the idea is improved and expanded towards a clever control part. This paper mainly focuses on the functional ideas and the state of research concerning the imaging tasks. Experiment and intermediate results of the imaging process are discussed. Different approaches of skin colour detection in diverse colour spaces have been tested. Skin colour detection is investigated whether skin colour can be monitored to improve work safety in terms of functional safety. To enhance versatility, several ideas are combined to form a clever gripping device

    Energetische und ökologische Analyse einer thermochemischen Bioraffinerie zur Herstellung von Plattformchemikalien

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    Bei der nachhaltigen Bereitstellung von Plattformchemikalien der organischen Chemie rücken biobasierte Reststoffe als Kohlenstoffquelle in den Fokus. Diese Studie beschäftigt sich mit der Konversion von Biomasse zu Plattformchemikalien in einer thermochemischen Bioraffinerie auf Basis einer Torrefizierung mit überhitztem Dampf. Auch die folgenden Separationsverfahren werden in die Betrachtung einbezogen. Zunächst wird ein verfahrenstechnischer Aufbau der Bioraffinerie und ihren nachgeschalteten Separationsverfahren entworfen. Anschließend werden die Prozesse analysiert und hinsichtlich der zentralen Material- und Energieströme kalkuliert. Die zu erwarteten Umweltbelastungen werden schließlich daraus abgeleitet und Hotspots identifiziert

    Representative Farm-Based Sustainability Assessment of the Organic Sector in Switzerland Using the SMART-Farm Tool

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    The agricultural sector faces serious environmental, social and economic challenges. In response, there has been a proliferation of labels and certifications aiming to ensure minimum farm sustainability performance. Organic agriculture (OA) a prominent example, having received substantial research attention relating to agronomic and environmental performance. While international OA movements are evolving to include broader sustainability aspirations, limited research exists on the social and economic performance of OA. To address this, we conducted a representative farm-based assessment of the Swiss organic sector to evaluate its contribution to sustainability across a wide range of themes based on the FAO Sustainability of Agriculture and Food Assessment (SAFA) Guidelines. We assessed 185 farms using the Sustainability Assessment and Monitoring RouTine (SMART) Farm Tool, chosen through stratified random sampling by farm type and agricultural zone. The results indicate that the Swiss organic sector makes a substantially positive contribution to sustainability, with average scores for theme goal achievement of 62% (Good Governance), 77% (Environmental Integrity), 70% (Economic Resilience), and 87% (Social Well-being). A set of 45 influential indicators (28 for plant production/mix farms and 30 for livestock farms) were selected based on the ability to explain variance (using Principal Component Analysis) and importance for goal achievement. The indicator sets explained a large amount of variation (ca. 70% for both farm types) and revealed a snapshot of management topics relevant to sustainability performance across the sector. These covered socio-political engagement, emissions to air and water, biodiversity, animal welfare, profitability, vulnerability, product quality, local economy, capacity building, and workplace risks. The spread of results across the sample, and comparisons to secondary data (literature and official statistics), revealed the importance of both well-studied issues (e.g., wide spread of energy consumption, variable yield levels/stability, local value chain dynamics) and more novel insights (e.g., strong political engagement, variable price premiums, lacking social security of farming families, insecure land tenure). We propose these topics as a basis for deeper analysis, designing improvement measures and conducting comparative research. This would bring much-needed breadth into the typically narrow debate surrounding the relative merits of OA

    PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study

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    Background: A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, safety, efficacy and indication profiles of PuraStat in a clinical setting. Methods: In this prospective observational multicentre pilot study, patients with acute non-variceal gastrointestinal bleeding (upper and lower) were included. Primary and secondary application of PuraStat was evaluated. Haemoglobin, prothrombin time, platelets and transfusion behaviour were documented before and after haemostasis. The efficacy of PuraStat was assessed during the procedure, at 3 days and 1 week after application. Results: 111 patients with acute gastrointestinal bleeding were recruited into the study. 70 percent (78/111) of the patients had upper gastrointestinal bleeding and 30% (33/111) had lower gastrointestinal bleeding. After primary application of PuraStat, initial haemostatic success was achieved in 94% of patients (74/79, 95% CI 88-99%), and in 75% of the patients when used as a secondary haemostatic product, following failure of established techniques (24/32, 95% CI 59-91%). The therapeutic success rates (absence of rebleeding) after 3 and 7 days were 91% and 87% after primary use, and 87% and 81% in all study patients. Overall rebleeding rate at 30 day follow-up was 16% (18/111). In the 5 patients who finally required surgery (4.5%), PuraStat allowed temporary haemostasis and stabilisation. Conclusions: PuraStat expanded the therapeutic toolbox available for an effective treatment of gastrointestinal bleeding sources. It could be safely applied and administered without complications as a primary or secondary therapy. PuraStat may additionally serve as a bridge to surgery in order to achieve temporary haemostasis in case of refractory severe bleeding, possibly playing a role in preventing immediate emergency surgery

    SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.

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    Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen consumption rate as a measure of mitochondrial respiration in B cells from patients with primary antibody deficiency. The highest oxygen consumption rate values were detected in three study participants with persistent polyclonal B cell lymphocytosis (PPBL). Exome sequencing identified germline mutations in SDHA, which encodes succinate dehydrogenase subunit A, in all three patients with PPBL. SDHA gain-of-function led to an accumulation of fumarate in PPBL B cells, which engaged the KEAP1-Nrf2 system to drive the transcription of genes encoding inflammatory cytokines. In a single patient trial, blocking the activity of the cytokine interleukin-6 in vivo prevented systemic inflammation and ameliorated clinical disease. Overall, our study has identified pathological mitochondrial retrograde signaling as a disease modifier in primary antibody deficiency

    Study of the BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

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    The decay BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} is studied in proton-proton collisions at a center-of-mass energy of s=13\sqrt{s}=13 TeV using data corresponding to an integrated luminosity of 5 fb1\mathrm{fb}^{-1} collected by the LHCb experiment. In the Λc+K\Lambda_{c}^+ K^{-} system, the Ξc(2930)0\Xi_{c}(2930)^{0} state observed at the BaBar and Belle experiments is resolved into two narrower states, Ξc(2923)0\Xi_{c}(2923)^{0} and Ξc(2939)0\Xi_{c}(2939)^{0}, whose masses and widths are measured to be m(Ξc(2923)0)=2924.5±0.4±1.1MeV,m(Ξc(2939)0)=2938.5±0.9±2.3MeV,Γ(Ξc(2923)0)=0004.8±0.9±1.5MeV,Γ(Ξc(2939)0)=0011.0±1.9±7.5MeV, m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV}, where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt Λc+K\Lambda_{c}^{+} K^{-} sample. Evidence of a new Ξc(2880)0\Xi_{c}(2880)^{0} state is found with a local significance of 3.8σ3.8\,\sigma, whose mass and width are measured to be 2881.8±3.1±8.5MeV2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV} and 12.4±5.3±5.8MeV12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}, respectively. In addition, evidence of a new decay mode Ξc(2790)0Λc+K\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-} is found with a significance of 3.7σ3.7\,\sigma. The relative branching fraction of BΛc+ΛˉcKB^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} with respect to the BD+DKB^{-} \to D^{+} D^{-} K^{-} decay is measured to be 2.36±0.11±0.22±0.252.36 \pm 0.11 \pm 0.22 \pm 0.25, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages
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