Zonal analysis of two high-speed inlets

Using a zonal technique, thin layer Navier-Stokes solutions for two high speed inlet geometries are presented and compared with experimental data. The first configuration consists of a 3-D inlet preceded by a sharp flat plate. Results with two different grids demonstrate the importance of adequate grid refinement in high speed internal flow computations. The fine grid solution has reasonably good agreement with experimental heat transfer and pressure values inside the inlet. The other configuration consists of a 3-D inlet mounted on a research hypersonic forebody. Numerical results for this configuration have good agreement with experimental pressure data along the forebody, but not inside the inlet. A more refined grid calculation is currently being done to better predict the flowfield in the inlet

Effect of bovine somatotropin on neutrophil functions and clinical symptoms during Streptococcus uberis mastitis.

The effect of recombinant bovine somatotropin (bST) on the chemiluminescence, diapedesis, and expression of adhesion receptors (CD11a, CD11b, CD18) of isolated polymorphonuclear leukocytes was studied. The plasma concentrations of insulin-like growth factor-I (IGF-I), bST, cortisol, and alpha-lactalbumin were also monitored. In addition, general and local clinical symptoms and the differentiation of circulating leukocytes were also studied during experimentally induced Streptococcus uberis mastitis in cows. Ten cows were infected with 500 cfu of S. uberis O140J in both left quarters. Five cows were subcutaneously treated with 500 mg of recombinant bST 7 d before and after infection, and 5 control cows received the excipient. General (fever, tachycardia, inappetance, and depression) and local symptoms (swelling, pain, firmness, and flecks in milk) were more acute, severe, and longer-lasting in control cows. Treatment with bST had no effect on chemiluminescence and diapedesis of circulating polymorphonuclear leukocytes and no effect on the expression of adhesion receptors. Recombinant bST induced significantly higher IGF-I and bST concentrations in plasma. The leukopenia observed after infection was less pronounced in the bST-treated cows, and the number of circulating band neutrophils and metamyelocytes was significantly lower in the treated group. The concentration of cortisol did not differ between both groups, but the blood concentration of alpha-lactalbumin significantly increased in both groups from 6 d after infection. These results showed that treatment with recombinant bST improves animal welfare by protecting the cows from severe local and general clinical symptoms during subsequent S. uberis mastitis, but that it has no effect on chemiluminescence, diapedesis, and the expression of adhesion receptors of circulating polymorphonuclear leukocytes

Modeling and Simulation Techniques for the NASA SLS Service Module Panel Separation Event; from Loosely-Coupled Euler to Fully-Coupled 6-DOF, Time-Accurate, Navier-Stokes Methodologies

An aerodynamic database has been generated for use by the Orion Multi-Purpose Crew Vehicle (MPCV) Program to analyze Service Module (SM) panel jettison from the NASA SLS vehicle. The database is a combination of CFD data for the panel aerodynamic coefficients, and MATLAB code written to query the CFD data. The Cart3D inviscid CFD flow solver was used to generate the panel aerodynamic coefficients for static panel orientations and free stream conditions that can occur during the jettison event. The MATLAB code performs the multivariate interpolation to obtain aerodynamic coefficients. The MATLAB code uses input for SM panel parameters and returns the SM panel aerodynamic force and moment coefficients for use with a Six-Degree-of-Freedom (6-DOF) motion solver to model the jettison event. This paper examines the accuracy of the sequential-static database approach by modeling the panel jettison event with a fully-coupled, time-dependent, viscous, moving-body CFD simulation. The fully-coupled simulation is obtained using the Loci/Chem unstructured Navier-Stokes CFD solver. The results show that the fully-coupled approach agrees well with the loosely-coupled database/6-DOF approach, indicating that unsteady effects are minimal for the panel jettison event. These results suggest that the database/6-DOF approach is sufficient. In addition, this paper presents the development of an uncertainty model for use in Monte Carlo analysis of the panel jettison event. Here viscous CFD simulations are obtained with Loci/Chem and compared to the inviscid CFD forces and moments. An uncertainty model based on model-form error and numerical error is presented

Archival ethics: The truth of the matter

This essay explores the question of whether records professionals are as aware of the ethical dimensions of their work as they should be. It consider first the historical and professional context of archival ethics, then examines a recent case about business archives involving the author that suggests the need for renewed attention to professional ethics, and concludes with a discussion about how archivists might reconsider the ethical dimensions of their work

Development of an Aerodynamic Analysis Method and Database for the SLS Service Module Panel Jettison Event Utilizing Inviscid CFD and MATLAB

This paper describes the development, testing, and utilization of an aerodynamic force and moment database for the Space Launch System (SLS) Service Module (SM) panel jettison event. The database is a combination of inviscid Computational Fluid Dynamic (CFD) data and MATLAB code written to query the data at input values of vehicle/SM panel parameters and return the aerodynamic force and moment coefficients of the panels as they are jettisoned from the vehicle. The database encompasses over 5000 CFD simulations with the panels either in the initial stages of separation where they are hinged to the vehicle, in close proximity to the vehicle, or far enough from the vehicle that body interference effects are neglected. A series of viscous CFD check cases were performed to assess the accuracy of the Euler solutions for this class of problem and good agreement was obtained. The ultimate goal of the panel jettison database was to create a tool that could be coupled with any 6-Degree-Of-Freedom (DOF) dynamics model to rapidly predict SM panel separation from the SLS vehicle in a quasi-unsteady manner. Results are presented for panel jettison simulations that utilize the database at various SLS flight conditions. These results compare favorably to an approach that directly couples a 6-DOF model with the Cart3D Euler flow solver and obtains solutions for the panels at exact locations. This paper demonstrates a method of using inviscid CFD simulations coupled with a 6-DOF model that provides adequate fidelity to capture the physics of this complex multiple moving-body panel separation event

The effects of physical activity on on-task and off-task behaviors of an elementary school student with ADHD

The purpose of this study was to explore and evaluate a possible connection between the participation in a physical activity and the on-task and off-task behaviors of an elementary school student with attention-deficit/hyperactivity disorder (ADHD). Specifically, the intervention phase applied in this study hoped to increase the on-task behaviors exhibited by the student while also decreasing off-task behaviors. After observing the student in the baseline phase, the intervention was applied based on the student’s choice of physical activity. Then, the researcher observed the student through whole interval recording of on-task behavior and partial interval recording of off-task behavior for ten minutes and in one minute intervals. Results showed an increase in her on-task behavior and a decrease in her off-task behavior during the times she participated in the physical activity. Additionally, social validity questionnaires completed by the student and classroom teacher show a positive experience with the intervention and the intention to continue using the physical activity to promote on-task behavior for the student

Pre-Therapeutic Dosimetry Employing Scandium-44 for Radiolabeling PSMA-617

In recent years, the positron emitter scandium-44 moved into the focus of research providing favorable nuclide properties for an application in nuclear medicine. Radiolabeling of PSMA-617 with scandium-44 as diagnostic match for [177Lu]Lu-PSMA-617 instead of gallium-68 would enable pre-therapeutic dosimetry in clinical setting. Due to the chemical similarities of scandium and lutetium, the in vitro and in vivo characteristics of [177Lu]Lu-PSMA-617 are more similar to [44Sc]Sc-PSMA-617 than to the 68Ga-compounds [68Ga]Ga-PSMA-617 or [68Ga]Ga-PSMA-11. [44Sc]Sc-PSMA-617 showed its potential in a clinical setting as a PET imaging agent of prostate cancer providing several advantages over gallium-68 labeled tracers. The longer half-life of the nuclide would allow, for example, an optimized patient management and treatment, long-term or late time point imaging as well as transportation to more distant PET centers. However, especially clinical applications like individual dosimetry or intraoperative applications are still under investigation

The occlusal plane inclination relative to craniofacial form: A cephalometric investigation

Background Objectives: The occlusal plane has been given much attention throughout the orthodontic literature. Studies have shown that the occlusal plane inclination varies relative to vertical and sagittal skeletal discrepencies. The Six Elements of Orofacial Harmony does not address the occlusal plane inclination as a parameter in diagnosis and treatment planning despite its spatial influence on the position of the chin. The occlusal plane inclination is considered a critical factor in treatment planning for orthognathic surgery. The objective of this study was to systematically evaluate the inclination of the occlusal plane (Op°) relative to various skeletal and dental cephalometric parameters. Methods: A sample of 105 pretreatment cephalometric radiographs, in subjects with a range of skeletal and dental morphological characteristics, was appraised. Differences in the Op° and AP measurements of pogonion relative to the GALL were evaluated among the various anteroposterior, vertical, and soft tissue facial convexity groups were compared. Correlation coefficients evaluating relationships among the cephalometric measurements were calculated. A stepwise regression analysis was performed to further elucidate the variables which contribute to changes in the Op°. Results: The occlusal plane inclination was most significantly correlated with SN-MPº, MPº, Pog\u27GALL, Pog-GALL, Pogc\u27- GALL, TVL-Pog, and S-Go. The regression analysis indicated that SN-MPº, PPº, Element IV Md Ant, PP-Msc, PP-1, Mp-Mic, Sn\u27-Me\u27, SNº, Element IV Mx Ant and Co-Gn are good predictors of Opº. There were statistically significant differences among all vertical groups for the mean Opº. The mean Opº was found to differ among Class II and III skeletal profiles and convex and concave soft tissue facial convexities. Conclusions: Opº varies relative to sagittal and vertical jaw dimensions. There is a strong relationship between the occlusal plane inclination and the vertical dimension. Hyperdivergent profiles tend to have steeper occlusal plane inclinations. Hypodivergent profiles tend to have flatter occlusal plane inclinations. There is a tendency towards steeper occlusal planes in Class II skeletal subjects and a flatter occlusal plane in Class III skeletal subjects. There is a tendency towards steeper occlusal planes in subjects with convex profiles and flatter occlusal planes in patients with concave profiles. The occlusal plane inclination is highly correlated with the measurement of soft tissue pogonion to the GALL. There is a strong correlation between the occlusal plane inclination and maxillary incisor inclination. The occlusal plane inclination should be considered when diagnosis and treatment planning to maximize dental and facial esthetics

(SNP045) Irene Eppard interviewed by Dorothy Noble Smith, transcribed by Sharon G. Marston

Records the reminiscences of Irene Eppard, (née Breeden), who was born and raised near Thorofare Mountain, in Rockingham County, Virgina, and lived there until the local families were evicted in 1936. Describes her early home and school life, popular community gatherings such as corn shucking and apple butter boiling parties, as well as courting, wedding and funeral rituals. Includes references to the gardens and livestock raised by the mountain people, their methods of food preservation and popular holiday traditions.https://commons.lib.jmu.edu/snp/1035/thumbnail.jp