The Islamic economic option (IEO) and the challenge of faith to the New World Order.

Islam is an ever-present reality in the political, economic and social life throughout the Arab-Islamic world. In this region, there exists a pervasive notion that Islam should be an integral part of all economic and political aspects of the state. At present, many nations across the Arab-Islamic world face political and economic instability and uncertainty. Since the legitimacy of many regimes in the region is consistently called into question, and since Islamic movements and political parties often form the strongest opposition, the emergence of an Islamic government is a strong possibility. Overall, the purpose of this thesis is to examine the concept of an Islamic Economic Option. This thesis looks at what extent Islamic economic concepts differ from Western economic models. It asks whether or not an IEO could serve as a practical alternative to Western models and form a program that is compatible with the global order. Given an Islamic opposition movement\u27s hypothetical rise to power, this thesis also asks what sort of economic strategy the group would follow and if it would retreat or remain involved in the global economy. (Abstract shortened by UMI.) Source: Masters Abstracts International, Volume: 44-03, page: 1215. Thesis (M.A.)--University of Windsor (Canada), 2005

Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial

Background Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain. Methods RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov , NCT00541047 . Findings Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths. Interpretation Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy. Funding Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society

Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial

Background Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear. Methods RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047. Findings Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths. Interpretation Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population

Kafala and Social Reproduction: Migration Governance Regimes and Labour Relations in the Gulf

With its roots in a system of imperial labour governance that ‘delegated responsibility over the conduct of individuals to other parties’ (AlShehabi 2019), kafala has often been understood as a policy by which states in the Gulf regulate, police, and exploit migrant labour. This chapter instead works to develop a concept of kafala as a migration governance regime, a way for states to integrate citizens as actors in the migration governance complex and, in doing so, obfuscate questions of accountability, transparency, and regulation. This is most keenly seen in the case of domestic workers who stand to benefit the least from recent reforms to kafala across the region. By focusing on the ways that kafala integrates individual households into the migration governance complex, this chapter aims to foreground the importance of the socially reproductive work done by migrant labourers to the Gulf, and attempts to explain the mechanisms through which their work sits outside the purview of the state’s governance of migrant labourers to the Gulf. The chapter attempts to explain the mechanisms through which domestic work is often excluded from wider considerations regarding migrant labour, even as domestic work is the most common form that migrant labour takes

Labour market regulation as global social policy: The case of nursing labour markets in Oman

This article examines global social policy formation in the area of skilled migration, with a focus on the Gulf Arab region. Across the globe, migration governance presents challenges to multiple levels of authority; its complexity crosses many scales and involves a multitude of actors with diverse interests. Despite this jurisdictional complexity, migration remains one of the most staunchly defended realms of sovereign policy control. Building on global social policy literature, this article examines how ‘domestic’ labour migration policies reflect the entanglement of multiple states’ and agencies’ interests. Such entanglements result in what we characterize as a ‘multiplex system’, where skilled-migration policies are formed within, and shaped by, globalized policy spaces. To illustrate, we examine policies that shape the nursing labour market in Oman during a period when the state aims to transition from dependence on an expatriate to an increasingly nationalized labour force. Engaging a case-study methodology including a survey of migrant healthcare workers, semi-structured interviews and data analysis, we find that nursing labour markets in Oman represent an example of global policy formation due to the interaction of domestic and expatriate labour policies and provisioning systems. The transnational structuring of policy making that emerges reflects a contingent process marked by conflicting outcomes. We contend that Oman’s nursing labour market is an example of new spaces where global social policies emerge from the tension of competing national state and market interests.Middle Eastern Studie

The Ontological (In)security of Similarity: Wahhabism versus Islamism in Saudi Foreign Policy

It has long been argued that identity matters in international relations. Yet, how identity impacts enmity and conflict among states remains the subject of debate. The existing literature asserts that differences in identity can be a source of conflict, whereas convergence and similarity lead to cooperation. Nevertheless, empirical evidence from the Middle East has long defied this hypothesis. The Kingdom of Saudi Arabia, which prides itself on being an Islamic model and claims Islamic leadership, has opposed the rise to power of Islamist movements in the Middle East. To address this paradox, this article builds on the growing literature on ontological security to propose a theoretical framework explaining how similarity can generate anxiety and identity risks. This framework, I argue, moves beyond traditional regime‐security approaches to reveal that security is not only physical but also ontological. I then illustrate the argument through a comparison of Saudi identity risks in the wake of the Iranian revolution (1979) and the ascendance of the Muslim Brotherhood to power in Egypt (2012). Ultimately, these cases provide intriguing insights into foreign policy behaviour during critical situations