Comparison of the effects of dexmedetomidine and remiphentanyl on emergence agitation after sevoflurane anesthesia in adults undergoing septoplasty operation: a randomized double-blind trial

OBJECTIVES: Sevoflurane is an ideal agent for anesthesia since its respiratory irritant effect is minimal during mask induction. Emergence agitation (EA) is a common problem after anesthesia with sevoflurane. In this study it was aimed to compare the effects of dexmedetomidine and remifentanyl on emergence agitation after sevoflurane anesthesia in adults undergoing septoplasty operation

Kinematic analysis and palaeoseismology of the Edremit Fault Zone: evidence for past earthquakes in the southern branch of the North Anatolian Fault Zone, Biga Peninsula, NW Turkey

The Edremit Fault Zone (EFZ) forms one of the southern segments of the North Anatolian Fault Zone (NAFZ) at the northern margin of the Edremit Gulf (Biga Peninsula, South Marmara Region, Turkey). Stratigraphic, structural and kinematic results indicate that basinward younging of the fault zone, in terms of a rolling-hinge mechanism, has resulted in at least three discrete Miocene to Holocene deformational phases: the oldest one (Phase 1) directly related to the inactive Kazda Detachment Fault, which was formed under N-S trending pure extension; Phase 2 is characterised by a strike-slip stress condition, probably related to the progression of the NAFZ towards the Edremit area in the Plio-Quaternary; and Phase 3 is represented by the high-angle normal faulting, which is directly interrelated with the last movement of the EFZ. Our palaeoseismic studies on the EFZ revealed the occurrence of three past surface rupture events; the first one occurred before 13178 BC, a penultimate event that may correspond to either the 160 AD or 253 AD historical earthquakes, and the youngest one can be associated with the 6 October 1944 earthquake (M-w=6.8). These palaeoseismic data indicate that there is no systematic earthquake recurrence period on the EFZ

Highly proton conductive phosphoric acid–nonionic surfactant lyotropic liquid crystalline mesophases and application in graphene optical modulators

Proton conducting gel electrolytes are very important components of clean energy devices. Phosphoric acid (PA, H3PO4·H2O) is one of the best proton conductors, but needs to be incorporated into some matrix for real device applications, such as into lyotropic liquid crystalline mesophases (LLCMs). Herein, we show that PA and nonionic surfactant (NS, C12H25(OCH2CH2)10OH, C12E10) molecules self-assemble into PANS–LLCMs and display high proton conductivity. The content of the PANS–LLCM can be as high 75% H3PO4·H2O and 25% 10-lauryl ether (C12H25(OCH2CH2)10OH, C12E10), and the mesophase follows the usual LLC trend, bicontinuous cubic (V1)–normal hexagonal (H1)–micelle cubic (I1), by increasing the PA concentration in the media. The PANS–LLCMs are stable under ambient conditions, as well as at high (up to 130 °C) and low (−100 °C) temperatures with a high proton conductivity, in the range of 10–2 to 10–6 S/cm. The mesophase becomes a mesostructured solid with decent proton conductivity below −100 °C. The mesophase can be used in many applications as a proton-conducting media as well as a phosphate source for the synthesis of various metal phosphates. As an application, we demonstrate a graphene-based optical modulator using supercapacitor structure formed by graphene electrodes and a PANS electrolyte. A PANS–LLC electrolyte-based supercapacitor enables efficient optical modulation of graphene electrodes over a range of wavelengths, from 500 nm to 2 μm, under ambient conditions

Pres-Final-2204: Developing Of A New Scale For Assessing The Adherence To Colchicines Treatment In Pediatric Patients With Fmf

PubMe

fever (MASIF) in a cohort of Turkish children

Objective. To develop and assess the validity and reliability of an adherence scale concerning medical treatment in paediatric FMF patients.Methods. The Medication Adherence Scale in FMF Patients (MASIF) is a 18-item questionnaire that evaluates adherence to medication in four domains. Validation of the instrument was accomplished in paediatric FMF patients (aged 2-18 years) under medication at least for 6 months. The first step was to build up the scale through qualitative approach (with interviews using semi-structured questions). Validation analyses included assessment of feasibility, face and content validity; construct validity, internal consistency and test-retest reliability.Results. One hundred and fifty patients with FMF were enrolled in the study. The mean age of the patients was 11.11 +/- 4.02 years and 48.7% of them were male. The MASIF was found to be feasible and valid for both face and content. It correlated with the Morisky Medication Adherence Scale as a gold standard thereby demonstrating good construct validity (r=0.5 15, p<0.001). Assessment of content validity identified four subscales. The internal consistency, Cronbach's alpha was 0.728. There was a positive and significant correlation between test and retest scores (r-0.843; p<0.001). Also, a significant correlation between parents' and children's reports (r=0.781, p<0.001).Conclusion. Based on these results, the use of this scale to assess and follow up the adherence to treatment in paediatric FMF patients under medical treatment is recommended