2,871 research outputs found

    on the choice of contact parameters for the forced response calculation of a bladed disk with underplatform dampers

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    Abstract Underplatform dampers (UPDs) are still in use to reduce the vibration amplitude of turbine blades and to shift the position of resonant frequencies. The dynamics of blades with UPDs is nonlinear and the analysis is challenging from both the experimental and the numerical point of view. A key point in obtaining a predictive numerical tool is the choice of the correct contact parameters (contact stiffness and friction coefficient) that are required as input to the contact model. The paper presents different approaches to choose these parameters: the contact stiffness in normal and tangential direction are both calculated and measured. The calculation is based on the analytical models in literature, the measurements are carried out on a dedicated test rig. The friction coefficient is also measured. Test results of the forced response of the same bladed disk with UPDs are available for each blade, they come from an experimental campaign under controlled excitation and centrifugal force. The forced response of the bladed disk is not used as a mean to tune the contact parameters, but rather as a validation tool: the effect of the different choices of contact parameters in the code is highlighted by the comparison of the calculated and experimental forced response of the bladed disk

    Vitamin D3 in High-Quality cow milk: an Italian case study

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    The quality-labeling category of High-Quality (HQ) milk defined by the Italian legislation must comply with specific requirements concerning rigorous breeder management, hygienic controls, fat and protein content, bacterial load, somatic cells, lactic acid content, and non-denatured soluble serum proteins. However, there is no specification for the vitamin D content of HQ milk. Moreover, the data on the vitamin D content of this milk category is very scarce. In the present study, the content of vitamin D3 was evaluated in HQ raw and pasteurized cow milk obtained from Italian cowsheds and supermarkets. The vitamin D3 content varied from not detected (less than 1 \ub5g L-1) to 17.0\ub12.0 \ub5g L-1 milk and was not related to the milk fat content. These results represent a case study including a significant although not exhaustive part of the contemporary Italian market of HQ milk. It was shown for the first time that HQ raw milk does not necessarily contain more vitamin D3, even though non-expert consumers likely to buy milk labeled as HQ could expect it. The vitamin D3 content in HQ pasteurized whole milk should be reported on the label of the milk package as a best practice of consumer information policy

    Resting state functional thalamic connectivity abnormalities in patients with post-stroke sleep apnoea: a pilot case-control study

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    OBJECTIVE: Sleep apnoea is common after stroke, and has adverse effects on the clinical outcome of affected cases. Its pathophysiological mechanisms are only partially known. Increases in brain connectivity after stroke might influence networks involved in arousal modulation and breathing control. The aim of this study was to investigate the resting state functional MRI thalamic hyper connectivity of stroke patients affected by sleep apnoea (SA) with respect to cases not affected, and to healthy controls (HC). PATIENTS AND METHODS: A series of stabilized strokes were submitted to 3T resting state functional MRI imaging and full polysomnography. The ventral-posterior-lateral thalamic nucleus was used as seed. RESULTS: At the between groups comparison analysis, in SA cases versus HC, the regions significantly hyper-connected with the seed were those encoding noxious threats (frontal eye field, somatosensory association, secondary visual cortices). Comparisons between SA cases versus those without SA, revealed in the former group significantly increased connectivity with regions modulating the response to stimuli independently to their potentiality of threat (prefrontal, primary and somatosensory association, superolateral and medial-inferior temporal, associative and secondary occipital ones). Further significantly functionally hyper connections were documented with regions involved also in the modulation of breathing during sleep (pons, midbrain, cerebellum, posterior cingulate cortices), and in the modulation of breathing response to chemical variations (anterior, posterior and para-hippocampal cingulate cortices). CONCLUSIONS: Our preliminary data support the presence of functional hyper connectivity in thalamic circuits modulating sensorial stimuli, in patients with post-stroke sleep apnoea, possibly influencing both their arousal ability and breathing modulation during sleep

    Guidelines on the use of inverse velocity method as a tool for setting alarm thresholds and forecasting landslides and structure collapses

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    Predicting the time of failure is a topic of major concern in the field of geological risk management. Several approaches, based on the analysis of displacement monitoring data, have been proposed in recent years to deal with the issue. Among these, the inverse velocity method surely demonstrated its effectiveness in anticipating the time of collapse of rock slopes displaying accelerating trends of deformation rate. However, inferring suitable linear trend lines and deducing reliable failure predictions from inverse velocity plots are processes that may be hampered by the noise present in the measurements; data smoothing is therefore a very important phase of inverse velocity analyses. In this study, different filters are tested on velocity time series from four case studies of geomechanical failure in order to improve, in retrospect, the reliability of failure predictions: Specifically, three major landslides and the collapse of an historical city wall in Italy have been examined. The effects of noise on the interpretation of inverse velocity graphs are also assessed. General guidelines to conveniently perform data smoothing, in relation to the specific characteristics of the acceleration phase, are deduced. Finally, with the aim of improving the practical use of the method and supporting the definition of emergency response plans, some standard procedures to automatically setup failure alarm levels are proposed. The thresholds which separate the alarm levels would be established without needing a long period of neither reference historical data nor calibration on past failure events

    Multi-analytical methodology to indagate the Pietraforte sandstone risk assessment

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    Pietraforte sandstone is one of the most important stone material used during Renaissance in Historic Center of Florence, a UNESCO World Heritage Site. One of its main uses as building material is rusticated block facades, a peculiar masonry technique typical of many historical Florentine palace (ie. Palazzo Pitti, Palazzo Medici Riccardi, Palazzo Strozzi, etc.). The characteristic color of Pietraforte, ranging from grey to yellow-ochreous, is a distinctive feature of the urban landscape of Florence. Stone rusticated blocks constitute elements with different overhangs which make them subject to decay phenomena due to weathering that, together with their intrinsic characteristics, can lead to detachment and loss of blocks (even of considerable size). The study of Pietraforte as a geoheritage with its morphological, mechanical, physical, mineralogical, and petrographic characterization is an important starting point to understand the possible evolution of decay processes. A multi-analytical characterization of this stone in several study cases allow the comparison of Florentine rusticated blocks used in different architectural registers (rough-hewn, smooth-faced and pillow rusticated), highlighting different behaviors of Pietraforte in distint architectural contexts. For example, convolute laminations and calcite veins (Pecchioni et al. 2007, Pecchioni et al. 2020), typical macroscopic characteristics of Pietraforte, show different behavior depending on the type of rusticated blocks. A multi-analytical methodology has been developed including sampling for physical, petrographic and mineralogical characterization and Non Destructive Techniques (NTD), using ultrasonic pulse velocity and sclerometric tests for mechanical behaviors (Salvatici et al. 2020, Centauro et al. 2022, Calandra et al. 2023). The main morphological features of Pietraforte from a geological point of view are investigated pondering each rusticated blocks as a rock mass and applied some methods of rock slope stability analysis. The study performed in this work aims to protect and preserve geoheritage stones finding a new and sustainable restoration and conservation approach for Pietraforte built Cultural Heritage weaknesses. Furthermore this multi analytical approach allow the diagnosis of the vulnerability of the stone material to detachments of scales, fragments and whole blocks that represent a damage to the monuments and a danger for people

    Submarine geomorphology of the Southwestern Sardinian continental shelf (Mediterranean Sea): Insights into the Last Glacial Maximum sea-level changes and related environments

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    During the lowstand sea-level phase of the Last Glacial Maximum (LGM), a large part of the current Mediterranean continental shelf emerged. Erosional and depositional processes shaped the coastal strips, while inland areas were affected by aeolian and fluvial processes. Evidence of both the lowstand phase and the subsequent phases of eustatic sea level rise can be observed on the continental shelf of Sardinia (Italy), including submerged palaeo-shorelines and landforms, and indicators of relict coastal palaeo-environments. This paper shows the results of a high-resolution survey on the continental shelf off San Pietro Island (southwestern Sardinia). Multisensor and multiscale data—obtained by means of seismic sparker, sub-bottom profiler chirp, multibeam, side scan sonar, diving, and uncrewed aerial vehicles—made it possible to reconstruct the morphological features shaped during the LGM at depths between 125 and 135 m. In particular, tectonic controlled palaeo-cliffs affected by landslides, the mouth of a deep palaeo-valley fossilized by marine sediments and a palaeo-lagoon containing a peri-littoral thanatocenosis (18,983 ± 268 cal BP) were detected. The Younger Dryas palaeo-shorelines were reconstructed, highlighted by a very well preserved beachrock. The coastal paleo-landscape with lagoon-barrier systems and retro-littoral dunes frequented by the Mesolithic populations was reconstructed

    Biofilm production in Staphylococcus epidermidis strains isolated from the skin of hospitalized patients: Genetic and phenotypic characteristics

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    A major virulence factor of Staphylococcus epidermidis is its ability to form biofilms, permitting it to adhere to a surface and, in turn, to form a mucoid layer on polymer surfaces. Multiple factors have been found to influence bacterial attachment. Currently, this bacterium is commonly associated with hospital infections as a consequence of its ability to colonize, albeit accidentally, medical devices. This study investigated the genetic and phenotypic formation of biofilm in 105 S. epidermidis strains isolated from the skin of hospitalized patients. Fifty-eight of these strains were positive for the mecA gene (MRSE) and 47 were found to be negative (MSSE). Genetic characterizations were performed for the detection of the mecA, icaADBC, atlE, aap, bhp, IS256 and agr groups by PCR. Biofilm production was examined by culturing the strains in TBS medium and TBS with 0.5 and 1% respectively of glucose, and a semiquantitative assay on tissue culture plates was used. Although a molecular analysis estimate of detailed biofilm formation is costly in terms of time and complexity, a semiquantitative assay can be proposed as a rapid and cheap diagnostic method for initial screening to discover virulent strains. We confirmed a close correlation between genetic and phenotypic characteristics, highlighting the fact that, when S. epidermidis isolates were cultured in TSB with 1% of glucose, an increase in biofilm production was observed, as confirmed by positivity for the ica locus by molecular analysis
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