Urine carcinoembryonic antigen levels are more useful than serum levels for early detection of Bilharzial and non-Bilharzial urinary bladder carcinoma: Observations of 43 Egyptian cases

BACKGROUND: Both urinary bilharziasis and urothelial neoplasia are associated with increased production of tissue carcinoembryonic antigen (CEA). PATIENTS AND METHODS: Urine and serum CEA were determined in 43 patients with urinary bladder carcinoma including 22 post bilharzial and 21 nonbiharzial cases, in addition to 10 normal control cases. RESULTS: A significant increase was detected in both urine and serum CEA levels with bladder carcinoma compared to control cases. Urinary CEA was significantly elevated in 86% of bilharzial, versus 62% in nonbilharzial bladder carcinoma. Only 10.5% of control cases had urinary CEA elevation. The mean urinary CEA in bilharzial, was higher than that of nonbilharzial carcinoma, but the difference was not statistically significant. There was a definite relationship between urine CEA and the stage of malignancy; the higher the stage, the higher the level of urine CEA. No relationship could be detected between the stage of malignancy and serum CEA, or between the grades of malignancy and urine or serum CEA levels. CONCLUSION: Urinary CEA is more useful than serum CEA in the early detection of urotherlial carcinoma particularly if provoked by bilharziasis. Its level is also correlated with the tumor stage

YAG Laser in the Treatment of Nail Psoriasis: Clinical and Dermoscopic Assessment

Background: The Nd:YAG laser has emerged as a promising modality for the management of nail psoriasis owing to its ability for deep penetration of the skin surface, which has the advantage of destroying deep vessels. Objective: To assess the efficacy and safety of Nd:YAG laser in treating nail psoriasis. Methods: The present study was a randomized controlled study, conducted on 20 patients of both sexes (age older than 12 years) with mild to moderate psoriasis with nail involvement. We utilized facial telangiectasia parameters of Nd:YAG laser and beam diameter of 2.5 mm. Laser energy started with 110 J/cm2 in the first session and 130 J/cm2 in the rest of the sessions. Sessions were performed once monthly for up to 6 sessions. Results: We found no statistically significant difference in total Nail Psoriasis Severity Index (NAPSI) and nail bed scores before and after treatment among the treated group. However, there was statistically significant improvement in nail matrix score after treatment. On the other hand, the control group did not show any statistically significant changes for all scores throughout the study, except for the nail matrix score mean difference (0.35 ± 1.23 vs -1.00 ± 1.86 in the treated group). The degree of dermoscopic improvement was evident in the treated group (45% vs 25% in the control group). However, it was not statistically significant because of small sample size. The patients' satisfaction and the external investigator's assessment showed statistically significant negative correlation with total NAPSI mean difference in the treated group. Conclusion: The role of Nd:YAG laser in nail psoriasis is still controversial

Impact of Augmented Reality on Pattern Designing Using Origami-Style among Clothing and Textile Students

The study aimed to examine the effects of augmented reality technology on the development of origami-style pattern designing skills among female students in the clothing and textile field, as well as to explore their attitudes towards this technology. The quasi-experimental approach was employed to achieve the research objectives, with a sample of 24 female students from the Fourth Grade of the Department of Clothing and Textile, Faculty of Home Economics at Al-Azhar University. The participants were divided into two groups: a control group of 12 students who studied in the traditional way, and an experimental group of 12 students who used augmented reality technology to learn. The study was conducted in the second semester of the academic year 2020/2021. The results showed that there was a statistically significant difference (at a significance level of 0.01) between the average scores of the control group and the experimental group in both cognitive achievement and skill performance, with the experimental group performing better. Additionally, the retention of learned information was higher among the experimental group, and they had a more positive attitude towards using augmented reality technology in learning

Early Childhood Mathematics Curriculum in the light of the standards of the National Council of Mathematics Teachers

This study aims at exploring the preschool mathematics curriculum in light of the National Council of Teachers of Mathematics Standards. The study researched a sample of (140) preschool educators. An analysis of the mathematical content of preschool Self-Learning curriculum was conducted, and Saudi preschool educators were surveyed, in terms of their educational practices, and the processes used in teaching mathematics in their classes In accordance with the U.S. national standards for mathematicians, it means the methods in which children interact with sports content or content, namely (problem solving- communication- logical thinking - representation - Connection), where the study showed that the reality of the components of the mathematics curriculum applied in kindergartens within Saudi Arabia achieved these standards at these levels was The application of representation, communication and connectivity are the most achieved in the self-learning curriculum units with ratios of (86.4%, 83%, 82%), respectively, while problem-solving and logical thinking have reached the minimum use in the classroom, indicating that these processes are the least interested in application from the sample point of view, with 80%, respectively, using them (80%, 67.80%), despite the critical importance of these two processes specifically in building mathematical concepts as they focus on the ability of the child to be focused on the ability of the child. To use his accumulated sports skills to meet challenges such as predicting and examining hypotheses in order to find a scientific solution to the sports situation

A universal low-noise analog receiver baseband in 65-nm CMOS

In this paper, a novel universal receiver baseband approach is introduced. The chain includes a post-mixer noise shaping blocker pre-filter, a programmable-gain post mixer amplifier (PMA) with blocker suppression, a differential ramp-based novel linear-in-dB variable gain amplifier and a Sallen–Key output buffer. The 1.2-V chain is implemented in a 65-nm CMOS process, occupying a die area of 0.45 mm2. The total power consumption of the baseband chain is 11.5 mW. The device can be tuned across a bandwidth of 700-KHz to 5.2-MHz with 20 kHz resolution and is tested for two distinct mobile-TV applications; integrated services digital broadcasting-terrestrial ISDB-T (3-segment f c = 700 kHz) and digital video broadcasting-terrestrial/handheld (DVB-T/H f c = 3.8 MHz). The measured IIP3 of the whole chain for the adjacent blocker channel is 24.2 and 24 dBm for the ISDB-T and DVB-T/H modes, respectively. The measured input-referred noise density is 10.5 nV/sqrtHz in DVB-T/H mode and 14.5 nV/sqrtHz in ISDB-T mode

Early Childhood Teachers Beliefs about Mathematics Teaching and Learning

The current research aimed to investigate the beliefs that early childhood teachers adopt about teaching and learning mathematics in the kindergartens of the Kingdom of Saudi Arabia. The teachers are role models for the child from whom he draws his knowledge, behavior, attitudes, concepts and experiences. and their classroom practice, which positively affects the level of the child and his attitudes towards the learning and teaching processes in general, and the mathematics course in particular, because of its importance in real life because it helps him to think, make decisions and solve problems he faces in his life. This has been confirmed by many researches and studies that the child is affected by his teachers beliefs, behaviors, decisions and dealings with him and the extent to which these beliefs are positive, which are the result of his personal and professional experience. One of the early childhood teachers, and the results of the study revealed that the responses of early childhood teachers about their beliefs about the processes of learning and teaching mathematics in general were positive, where most of the beliefs came to a large degree. This indicates that the teachers of this stage have positive opinions and ideas about the learning and teaching processes and the educational system, which affects their teaching efficiency, which is reflected in the child’s level of mathematics in an effective and positive manner. That is why the researchers recommend the necessity of providing workshops to develop, develop and support positive beliefs. The teachers of this stage are in line with modern educational trends

Internet-based search of randomised trials relevant to mental health originating in the Arab world

BACKGROUND: The internet is becoming a widely used source of accessing medical research through various on-line databases. This instant access to information is of benefit to busy clinicians and service users around the world. The population of the Arab World is comparable to that of the United States, yet it is widely believed to have a greatly contrasting output of randomised controlled trials related to mental health. This study was designed to investigate the existence of such research in the Arab World and also to investigate the availability of this research on-line. METHODS: Survey of findings from three internet-based potential sources of randomised trials originating from the Arab world and relevant to mental health care. RESULTS: A manual search of an Arabic online current contents service identified 3 studies, MEDLINE, EMBASE, and PsycINFO searches identified only 1 study, and a manual search of a specifically indexed, study-based mental health database, PsiTri, revealed 27 trials. CONCLUSION: There genuinely seem to be few trials from the Arab world and accessing these on-line was problematic. Replication of some studies that guide psychiatric/psychological practice in the Arab world would seem prudent

Search for low-mass dark matter via bremsstrahlung radiation and the Migdal effect in SuperCDMS

We present a new analysis of previously published SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to 220  MeV/c2 at 2.7×10−30  cm2 via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to 30  MeV/c2 at 5.0×10−30  cm2

Need for recovery amongst emergency physicians in the UK and Ireland: A cross-sectional survey

OBJECTIVES: To determine the need for recovery (NFR) among emergency physicians and to identify demographic and occupational characteristics associated with higher NFR scores. DESIGN: Cross-sectional electronic survey. SETTING: Emergency departments (EDs) (n=112) in the UK and Ireland. PARTICIPANTS: Emergency physicians, defined as any registered physician working principally within the ED, responding between June and July 2019. MAIN OUTCOME MEASURE: NFR Scale, an 11-item self-administered questionnaire that assesses how work demands affect intershift recovery. RESULTS: The median NFR Score for all 4247 eligible, consented participants with a valid NFR Score was 70.0 (95% CI: 65.5 to 74.5), with an IQR of 45.5-90.0. A linear regression model indicated statistically significant associations between gender, health conditions, type of ED, clinical grade, access to annual and study leave, and time spent working out-of-hours. Groups including male physicians, consultants, general practitioners (GPs) within the ED, those working in paediatric EDs and those with no long-term health condition or disability had a lower NFR Score. After adjusting for these characteristics, the NFR Score increased by 3.7 (95% CI: 0.3 to 7.1) and 6.43 (95% CI: 2.0 to 10.8) for those with difficulty accessing annual and study leave, respectively. Increased percentage of out-of-hours work increased NFR Score almost linearly: 26%-50% out-of-hours work=5.7 (95% CI: 3.1 to 8.4); 51%-75% out-of-hours work=10.3 (95% CI: 7.6 to 13.0); 76%-100% out-of-hours work=14.5 (95% CI: 11.0 to 17.9). CONCLUSION: Higher NFR scores were observed among emergency physicians than reported in any other profession or population to date. While out-of-hours working is unavoidable, the linear relationship observed suggests that any reduction may result in NFR improvement. Evidence-based strategies to improve well-being such as proportional out-of-hours working and improved access to annual and study leave should be carefully considered and implemented where feasible