21 research outputs found

    Poly (acrylonitrile-co-methyl methacrylate) nanoparticles: I. Preparation and characterization

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    This work concerns the preparation and characterization of poly (acrylonitrile-co-methyl methacrylate) Copolymer, P(AN-co-MMA), nano-particles using precipitation polymerization technique. Potassium per-sulfate redox initiation system was used to perform polymerization process in an alcoholic aqueous system. The impact of different polymerization conditions such as comonomer concentration and ratio, polymerization time, polymerization temperatures, initiator concentration and co-solvent composition on the polymerization yield and particle size was studied. Maximum polymerization yield, 70%, was obtained with MMA:AN (90%:10%) comonomer composition. Particle sizes ranging from 16 nm to 1483 nm were obtained and controlled by variation of polymerization conditions. The co-polymerization process was approved by FT-IR and TGA analysis. The copolymer composition was investigated by nitrogen content analysis. Copolymers with a progressive percentage of PAN show thermal stabilities close to PAN Homopolymer. SEM photographs prove spherical structure of the produced copolymers. The investigated system shows promising future in the preparation of nanoparticles from comonomers without using emulsifiers or dispersive agents

    Non-mastoidectomy Cochlear Implant Approaches: A Literature Review

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    Abstract Introduction Posterior tympanotomy approach for cochlear implant (CI) surgery, has been the most commonly used worldwide with current 0.7% rate of facial nerve injury. Non-mastoidectomy CI approaches include the suprameatal approach (SMA) and its modifications, the transcanal approach and its modifications and the pericanal approach for electrode insertion. Objectives The objective of this study was to review the literature regarding nonmastoidectomy CI approaches. Data Synthesis A search was performed in the LILACS, MEDLINE, SciELO, PubMed databases and Cochrane Library in February 2015, and the key words used in the search were CI, SMA, transcanal approach, pericanal approach, or electrode extrusion. About 30 studies that met the criteria described in "Study Selection" were read in full. The studies showed 1014 patients that underwent CI by SMA or its modifications, 266 CI patients treated by transcanal approach or its modifications, and 15 patients implanted by the pericanal approach. Reported complication with SMA was 99 (9.8%) minor and 13 (1.3%) major. With transcanal, there were 24 complications; 19 (7.1%) minor and 5 (1.9%) major. No post-operative complication was reported in pericanal approach. Studies showed no reported facial nerve paresis or paralysis in all non-mastoidectomy approaches. Conclusion Complications rates with non-mastoidectomy approaches are similar to those found in the mastoidectomy approach. Thus, non-mastoidectomy approaches may be an alternative in cases where the conventional mastoidectomy approach is difficult to perform. It would be helpful for CI surgeons to become familiarized with these approaches
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