310 research outputs found
Non-Continuous Double Barrier Reflected BSDES With Jumps under a Stochastic Lipschitz Coefficient
Converse comparison theorems for backward doubly stochastic differential equations
Converse and general converse comparison theorems are proved for backward doubly stochastic differential equations
Approximation scheme for solutions of backward stochastic differential equations via the representation theorem
Pharyngeal-cervical-brachial syndrome: An atypical case of Guillain-Barre syndrome with anti-sulfatide IgM antibodies
Pharyngeal-cervical-brachial (PCB) syndrome, a rare form of Guillain-Barre syndrome (GBS) is defined by rapidly progressive oropharyngeal and cervicobrachial weakness associated with areflexia in the upper limbs. We report the observation of a 30-year-old adult male who presented, 10 days after acute diarrhea, oculomotor and severe bulbar palsy followed by cervicobrachial diparesis with hyporeflexia in the upper limbs. Cerebral magnetic resonance imaging (MRI), the otorhinolaryngological examination, the cerebrospinal fluid (CSF) analysis, the prostigmine test were normal as was the electromyography (EMG) performed on day 10. Laboratory test results such as antiacetylcholin receptor antibodies were negative. At the EMG performed on day 18, there were some signs of demyelination; the diagnosis of PCB syndrome was made. Determination of antiganglioside antibodies revealed positive Anti-sulfatide IgM antibodies. After administration of immunoglobulin therapy, symptoms got better with a complete recovery in 6 weeks.
French title: Syndrome pharyngo-cervico-brachial : Un cas atypique de syndrome de guillainbarre avec des anticorps Anti-Sulfatide IgM
 
Molecular characterization of Fom-1 gene and development of functional markers for molecular breeding of resistance to Fusarium race 2 in melon
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High-performance FPGA implementation of the secure hash algorithm 3 for single and multi-message processing
The secure hash function has become the default choice for information security, especially in applications that require data storing or manipulation. Consequently, optimized implementations of these functions in terms of Throughput or Area are in high demand. In this work we propose a new conception of the secure hash algorithm 3 (SHA-3), which aim to increase the performance of this function by using pipelining, four types of pipelining are proposed two, three, four, and six pipelining stages. This approach allows us to design data paths of SHA-3 with higher Throughput and higher clock frequencies. The design reaches a maximum Throughput of 102.98 Gbps on Virtex 5 and 115.124 Gbps on Virtex 6 in the case of the 6 stages, for 512 bits output length. Although the utilization of the resource increase with the increase of the number of the cores used in each one of the cases. The proposed designs are coded in very high-speed integrated circuits program (VHSIC) hardware description language (VHDL) and implemented in Xilinx Virtex-5 and Virtex-6 A field-programmable gate array (FPGA) devices and compared to existing FPGA implementations
Pantothenate kinase associated neurodegeneration: Case series
Background: Neurodegeneration with brain iron accumulation (NBIA) encompasses a heterogeneous group of hereditary disorders characterized by iron deposition particularly in the basal ganglia. Pantothenate kinaseâassociated neurodegeneration (PKAN) is the most common NBIA. PKAN, due to mutation in the PANK 2 gene has two main presentations.Case report: The classic form usually starts in the first decade of life with severe dystonia, dysarthria, parkinsonism, pyramidal, visual signs, and cognitive disturbances with an aggressive course, leading to death by the second decade of life. The atypical form is characterized by a slower progression, and a more benign course. A brain magnetic resonance imaging usually shows the eye of the tiger sign. Here, we report four cases whose age of onset and clinical presentation suggests typical form of PKAN.Conclusion: In sum, the data of our patients corroborated those of the classic form of PKAN. The perspective in this entity is the development of rational therapeutics targeting the primary biochemical anomaly, with compounds that bypass the defective PANK2 enzyme including phantasein, phosphopanthethein and coenzyme A.
French title :Neurodegenerescence associee a un deficit en pantothenate kinase : Serie de cas
Introduction : La neurodĂ©gĂ©nĂ©rescence avec accumulation intracĂ©rebrale de fer (NBIA) constitue un groupe hĂ©tĂ©rogĂšne de pathologies hĂ©rĂ©ditaires caractĂ©risĂ©es par un dĂ©pĂŽt de fer en particulier dans les noyaux gris centraux. La neurodĂ©gĂ©nĂ©rescence associĂ©e Ă un dĂ©ficit en Pantothenate kinase (PKAN) reprĂ©sente la forme la plus courante de NBIA. Elle est due Ă une mutation dans le gĂšne PANK 2 et comporte 2 formes cliniques.Cas cliniques : La forme classique dĂ©bute gĂ©nĂ©ralement au cours de la premiĂšre dĂ©cade par une dystonie sĂ©vĂšre, une dysarthrie, un parkinsonisme, des signes pyramidaux, visuels et des troubles cognitifs dâĂ©volution sĂ©vĂšre entrainant la mort au cours de la deuxiĂšme dĂ©cade. La forme atypique est caractĂ©risĂ©e par une progression plus lente et une Ă©volution plus bĂ©nigne. Une imagerie par rĂ©sonance magnĂ©tique cĂ©rĂ©brale montre gĂ©nĂ©ralement le signe des yeux de tigre. Nous rapportons ici quatre cas dont lâĂąge dâapparition et la prĂ©sentation clinique suggĂšrent une forme typique de PKAN.Conclusion : En somme, les donnĂ©es de nos patients corroborent celles de la forme classique de PKAN. La perspective de cette entitĂ© est le dĂ©veloppement de thĂ©rapies rationnelles ciblant l'anomalie biochimique primaire, avec des composĂ©s qui contournent l'enzyme PANK2 dĂ©fectueuse, notamment la fantasĂ©ine, la phosphopanthĂ©thĂ©ine et la coenzyme A
Unilateral oculomotor nerve palsy caused by a basilar artery dolichoectasia: Paralysie unilatérale du nerf oculomoteur commun causée par une dolichoectasie du tronc basilaire
Lâatteinte isolĂ©e de lâun des nerfs crĂąniens oculomoteurs due Ă une dolicho-ectasie vertĂ©bro-basilaire est rare. Nous rapportons le cas dâune patiente ayant prĂ©sentĂ© une diplopie horizontale dâinstallation aigue liĂ©e Ă une paralysie partielle du nerf oculomoteur commun gauche. La neuro-imagerie a mis en Ă©vidence une anomalie vasculaire de lâartĂšre basilaire suggĂ©rant une dolicho-ectasie Ă proximitĂ© de la partie interne du pĂ©doncule cĂ©rĂ©bral gauche. La patiente a complĂštement et spontanĂ©ment rĂ©cupĂ©rĂ© aprĂšs un mois. Ce cas illustre une Ă©tiologie rare de paralysie partielle du nerf oculomoteur commun Ă©pargnant la pupille.
Isolated dysfunction of the third cranial nerve due to vertebrobasilar dolichoectasia is uncommon. We report a case of a patient who presented with recent onset of horizontal diplopia due to left partial third nerve palsy. Neuroimaging revealed a vascular abnormality in the basilar artery suggesting a dolichoectasia next with a leftward deviation to the internal side of the left cerebral peduncle. The patient fully and spontaneously recovered after one month. This case illustrates a rare etiology of a partial oculomotor nerve palsy sparing the pupil
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