Converse comparison theorems for backward doubly stochastic differential equations

Converse and general converse comparison theorems are proved for backward doubly stochastic differential equations

Pharyngeal-cervical-brachial syndrome: An atypical case of Guillain-Barre syndrome with anti-sulfatide IgM antibodies

Pharyngeal-cervical-brachial (PCB) syndrome, a rare form of Guillain-Barre syndrome (GBS) is defined by rapidly progressive  oropharyngeal and cervicobrachial weakness associated with areflexia in the upper limbs. We report the observation of a 30-year-old adult male who presented, 10 days after acute diarrhea, oculomotor and severe bulbar palsy followed by cervicobrachial diparesis with  hyporeflexia in the upper limbs. Cerebral magnetic resonance imaging (MRI), the otorhinolaryngological examination, the cerebrospinal fluid (CSF) analysis, the prostigmine test were normal as was the electromyography (EMG) performed on day 10. Laboratory test results such as antiacetylcholin receptor antibodies were negative. At the EMG performed on day 18, there were some signs of demyelination; the  diagnosis of PCB syndrome was made. Determination of antiganglioside antibodies revealed positive Anti-sulfatide IgM antibodies. After administration of immunoglobulin therapy, symptoms got better with a complete recovery in 6 weeks. French title: Syndrome pharyngo-cervico-brachial : Un cas  atypique de syndrome de guillainbarre avec des anticorps Anti-Sulfatide IgM &nbsp

Molecular characterization of Fom-1 gene and development of functional markers for molecular breeding of resistance to Fusarium race 2 in melon

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High-performance FPGA implementation of the secure hash algorithm 3 for single and multi-message processing

The secure hash function has become the default choice for information security, especially in applications that require data storing or manipulation. Consequently, optimized implementations of these functions in terms of Throughput or Area are in high demand. In this work we propose a new conception of the secure hash algorithm 3 (SHA-3), which aim to increase the performance of this function by using pipelining, four types of pipelining are proposed two, three, four, and six pipelining stages. This approach allows us to design data paths of SHA-3 with higher Throughput and higher clock frequencies. The design reaches a maximum Throughput of 102.98 Gbps on Virtex 5 and 115.124 Gbps on Virtex 6 in the case of the 6 stages, for 512 bits output length. Although the utilization of the resource increase with the increase of the number of the cores used in each one of the cases. The proposed designs are coded in very high-speed integrated circuits program (VHSIC) hardware description language (VHDL) and implemented in Xilinx Virtex-5 and Virtex-6 A field-programmable gate array (FPGA) devices and compared to existing FPGA implementations

Pantothenate kinase associated neurodegeneration: Case series

Background: Neurodegeneration with brain iron accumulation (NBIA) encompasses a heterogeneous group of hereditary disorders characterized by iron deposition particularly in the basal ganglia. Pantothenate kinase‐associated neurodegeneration (PKAN) is the most common NBIA. PKAN, due to mutation in the PANK 2 gene has two main presentations.Case report: The classic form usually starts in the first decade of life with severe dystonia, dysarthria, parkinsonism, pyramidal, visual signs, and cognitive disturbances with an aggressive course, leading to death by the second decade of life. The atypical form is characterized by a slower progression, and a more benign course. A brain magnetic resonance imaging usually shows the eye of the tiger sign. Here, we report four cases whose age of onset and clinical presentation suggests typical form of PKAN.Conclusion: In sum, the data of our patients corroborated those of the classic form of PKAN. The perspective in this entity is the development of rational therapeutics targeting the primary biochemical anomaly, with compounds that bypass the defective PANK2 enzyme including phantasein, phosphopanthethein and coenzyme A.   French title :Neurodegenerescence associee a un deficit en pantothenate kinase : Serie de cas Introduction : La neurodégénérescence avec accumulation intracérebrale de fer (NBIA) constitue un groupe hétérogène de pathologies héréditaires caractérisées par un dépôt de fer en particulier dans les noyaux gris centraux. La neurodégénérescence associée à un déficit en Pantothenate kinase (PKAN) représente la forme la plus courante de NBIA. Elle est due à une mutation dans le gène PANK 2 et comporte 2 formes cliniques.Cas cliniques : La forme classique débute généralement au cours de la première décade par une dystonie sévère, une dysarthrie, un parkinsonisme, des signes pyramidaux, visuels et des troubles cognitifs d‘évolution sévère entrainant la mort au cours de la deuxième décade. La forme atypique est caractérisée par une progression plus lente et une évolution plus bénigne. Une imagerie par résonance magnétique cérébrale montre généralement le signe des yeux de tigre. Nous rapportons ici quatre cas dont l‘âge d‘apparition et la présentation clinique suggèrent une forme typique de PKAN.Conclusion : En somme, les données de nos patients corroborent celles de la forme classique de PKAN. La perspective de cette entité est le développement de thérapies rationnelles ciblant l'anomalie biochimique primaire, avec des composés qui contournent l'enzyme PANK2 défectueuse, notamment la fantaséine, la phosphopanthéthéine et la coenzyme A

Unilateral oculomotor nerve palsy caused by a basilar artery dolichoectasia: Paralysie unilatérale du nerf oculomoteur commun causée par une dolichoectasie du tronc basilaire

L’atteinte isolée de l’un des nerfs crâniens oculomoteurs due à une dolicho-ectasie vertébro-basilaire est rare. Nous rapportons le cas d’une patiente ayant présenté une diplopie horizontale d’installation aigue liée à une paralysie partielle du nerf oculomoteur commun gauche. La neuro-imagerie a mis en évidence une anomalie vasculaire de l’artère basilaire suggérant une dolicho-ectasie à proximité de la partie interne du pédoncule cérébral gauche. La patiente a complètement et spontanément récupéré après un mois. Ce cas illustre une étiologie rare de paralysie partielle du nerf oculomoteur commun épargnant la pupille. Isolated dysfunction of the third cranial nerve due to vertebrobasilar dolichoectasia is uncommon. We report a case of a patient who presented with recent onset of horizontal diplopia due to left partial third nerve palsy. Neuroimaging revealed a vascular abnormality in the basilar artery suggesting a dolichoectasia next with a leftward deviation to the internal side of the left cerebral peduncle. The patient fully and spontaneously recovered after one month. This case illustrates a rare etiology of a partial oculomotor nerve palsy sparing the pupil