Some physiological and biochemical properties of silver nanoparticles impact on chickpea (Cicer arietinum L.) plants

Günümüzde nanoteknoloji temelli ürünlere artan talep ile birlikte nanopartiküllerin çevreye yayılma riskleri artmaktadır. Nanopartiküller içinde gümüş nanopartiküller (AgNP) antimikrobiyal özelliklerinden dolayı geniş çapta kullanılmaktadır. Bu nedenle AgNP'lerin mikroorganizmalara ve hayvansal organizmalara olan etkileri araştırılmaktadır, fakat bitkilerle etkileşimleri hakkında az sayıda çalışma bulunmaktadır. Bu çalışmanın amacı gümüş nanopartiküllerin nohut bitkisinde (Cicer arietinum L.) biyokimyasal ve fizyolojik parametrelere olan etkisinin incelenmesidir. Çalışmada nohut bitkisinin farklı konsantrasyonlarda AgNP uygulanarak oransal su içeriği, toplam klorofil miktarı, antioksidan enzim aktiviteleri ve lipid peroksidasyonu analiz edildi. AgNP uygulamasının nohut bitkisinin yapraklarında oransal su içeriğinde azalma, bununla birlikte lipid peroksidasyonunda artışa neden olduğu gözlendi. 40 ve 80 mg/L AgNP uygulamalarının antioksidan enzim aktivitesinde inhibisyona neden olduğu belirlendi. Çalışmamızdan elde edilen sonuçlara göre, C. arietinum bitkisinin düşük doz AgNP uygulamalarında oksidatif hasara karşı koruma mekanizmasının daha iyi olduğu, yüksek doz AgNP uygulamalarına ise nohut bitkisinin hassas olabileceği söylenebilir.Nowadays the demand to nanotechnology-based products increase the risks of the nanoparticle spread to the environment. Among nanoparticles the silver nanoparticles (AgNPs) are widely used due to their antibacterial properties. Therefore studies are performed concerning the effects of AgNPs on microorganisms and animal organisms, however there are studies related to the interaction with plants. The aim of this study was to evaluate the effects of silver nanoparticles (AgNPs) on bicohemical and physiological parameters in chickpea (Cicer arietinum L.) plant. Different concentrations of silver few nanoparticle (AgNPs) were applied and RWC, total chlorophyll content, antioxidant enzyme activities and MDA content were analysed. AgNP application resulted in a reduction of the relative water content, however an increase in lipid peroxidation in the leaves of chickpea plants. 40 and 80 mg/L AgNP treatments caused an inhibition of antioxidant enzyme activity. According to the results obtained from this study, in the low doses of AgNP applications, C. arietinum could have better protection mechanisms against oxidative damage, and it can be said that chickpea plant is likely to be sensitive to high doses of AgNP

Ballistic strength of aerated concrete

In regional studies conducted by the Law Enforcement Agency and the Armed Forces within the scope of counter-terrorism activities, to ensure peace and security throughout the country and for the police and military personnel to provide security services, the need to produce different solutions has arisen in the face of attacks on the security points established at many important points, especially at the entrance and exit points of the cities. In this context, by changing the direction and angle of the wall types made of aerated concrete used in construction techniques, 7 variations were tested on these wall types with materials formed with adhesive mortar+plaster, monolithic elastomer polyurea, and non-Newtonian fluid, and the strength of these materials were tested with BR6 and BR7 bullets. The main purpose of this study was to determine the most suitable material in terms of security parameters in the shortest time and at a low cost and to create a reliable structure for security cabins. At the end of the study, the best results were obtained with the shots made on the narrow surface of the aerated concrete and the shots made on the platform formed with non-Newtonian fluid

Silver nanoparticles induced genotoxicity and oxidative stress in tomato plants

Fazilet Özlem Çekiç (Aksaray, Yazar) Sefa Ekinci (Aksaray, Yazar)Among nanoparticles, silver nanoparticles (AgNPs) are intensively used in many materials owing to their antibacterial effects. In the present study different concentrations of AgNPs in Hoagland solution were applied to tomato seedlings. Total chlorophyll content, relative water content (RWC), antioxidant enzyme activities, and malondialdehyde content (MDA) as well as the genomic template stability (GTS) were analyzed. The intersimple sequence repeat polymerase chain reaction assay (ISSR-PCR) was used to determine the genotoxic effects of AgNPs on DNA. RWC did not change under AgNPs treatments; however, total chlorophyll content was significantly reduced by AgNPs applications. ISSR profiles demonstrated a consistent increase in polymorphic bands by the increase in the concentration of AgNPs. GTS value was also reduced depending on the concentration of AgNPs. SOD and APX activities were increased under low AgNPs treatments; however, these activities were decreased under high concentrations of AgNPs treatments. Tomato plants could be sensitive to AgNPs within the increase in MDA content in all of the AgNPs treatments. AgNPs nanotoxicity could be quite dose-dependent. AgNPs could also have negative effects on tomato plants by enhancing DNA damage and lipid peroxidation

THE EFFECT OF CARVACROL UPON EXPERIMENTALLY INDUCED DIABETIC NEUROPATHY AND NEUROPATHIC PAIN IN RATS

Diabetic neuropathies are the most frequent complication of diabetes. While numerous meta-bolic pathways are disrupted in diabetic neuropathy, oxidative stress has been indicated as a significant reason for this condition. In this study, the effect of carvacrol, which has antioxidant effects, on experi-mental diabetic neuropathy and neuropathic pain was investigated. Alloxan was used to induce diabetes in the experiment. Diabetes was created by administering 120 mg/kg of alloxan intraperitoneally (i.p) once a day for 3 days. Rats with a blood glucose concentration above 250 mg/kg in the blood taken from the tail veins at the end of three days were considered diabetic. Rats were categorized under healthy con-trol (HG), alloxan-induced hyperglycemia (AG), and alloxan-induced hyperglycemia + carvacrol-treated (ACG) groups. Carvacrol was i.p injected at 50 mg/kg dose to the ACG (n = 6) group of rats with hyper-glycemia. The same volume of distilled water as the solvent was applied in the same way to AG (n = 6) and HG (n = 6) rat groups. This procedure was repeated once a day for three months. Carvacrol showed an anti-hyperglycemic effect in diabetic rats, a protective effect against lowering pain threshold, and an-algesic activity in rat paws. Carvacrol prevented the oxidant/antioxidant balance from changing in favor of oxidants. The results supported that carvacrol is an agent against alloxan-induced peripheral diabetic neuropathic pain

sj-docx-1-imj-10.1177_10815589241232366 – Supplemental material for Compliance with guideline recommendations in the management of patients with hospitalized community-acquired pneumonia

Supplemental material, sj-docx-1-imj-10.1177_10815589241232366 for Compliance with guideline recommendations in the management of patients with hospitalized community-acquired pneumonia by Pinar Bakir Ekinci, Emre Kara, Gulcin Telli Dizman, Sefa Metin, Ahmet Cagkan Inkaya, Kutay Demirkan, Lutfi Coplu and Serhat Unal in Journal of Investigative Medicine</p