17 research outputs found
Sunscreen-Assisted Selective Photochemical Transformations
In this review, we describe a simple and general procedure to accomplish selective photochemical reaction sequences for two chromophores that are responsive to similar light frequencies. The essence of the method is based on the exploitation of differences in the molar absorptivity at certain wavelengths of the photosensitive groups, which is enhanced by utilizing light-absorbing auxiliary filter molecules, or “sunscreens”. Thus, the filter molecule hinders the reaction pathway of the least absorbing molecule or group, allowing for the selective reaction of the other. The method was applied to various photochemical reactions, from photolabile protecting group removal to catalytic photoinduced olefin metathesis in different wavelengths and using different sunscreen molecules. Additionally, the sunscreens were shown to be effective also when applied externally to the reaction mixture, avoiding any potential chemical interactions between sunscreen and substrates and circumventing the need to remove the light-filtering molecules from the reaction mixture, adding to the simplicity and generality of the method
Photoactivation of Ruthenium Phosphite Complexes for Olefin Metathesis
The commercially
available catalyst <b><i>cis</i>-Caz-1</b> is extremely
robust, especially when reactions are performed in
an atmosphere of air. This phosphite-containing ruthenium complex
only shows olefin metathesis activity at high temperatures. Herein,
we report photoactivation of <b><i>cis</i>-Caz-1</b> at room temperature with UVA light. Thus, a wide variety of olefin
metathesis reactions was performed under mild conditions with good
yields. In addition, we report the synthesis, characterization, and
catalytic activity of a phosphite-chelated ruthenium benzylidene complex, <b><i>cis</i>-PhosRu-1</b>, which can be efficiently activated
either by irradiation with visible light (λ = 405 nm) or by
heat
Synthesis and Catalytic Properties of Sulfur-Chelated Ruthenium Benzylidenes Bearing a Cyclic (Alkyl)(amino)carbene Ligand
Sulfur-chelated
ruthenium olefin metathesis precatalysts that possess
cyclic (alkyl)(amino)carbenes (CAAC) can benefit from the synergetic
effect of both ligands. Changing the steric bulk of the CAAC ligand
by using different substitution patterns was shown to affect the geometry
of the complexes produced and determined whether the complexes could
be catalytically dormant. The <i>cis</i>-dichloro latent
catalysts could be activated both by heat or light, even in the visible
region, for representative acyclic diene metathesis and ring-opening
metathesis polymerization reactions, olefin cross-metathesis, and
ring-closing metathesis without isomerization byproducts. Thus, these
complexes were shown to combine the uniqueness of CAAC-containing
Ru olefin metathesis catalysts with the advantage of the thermal and
photolatency imposed by sulfur chelation of the benzylidene
Synthesis and Catalytic Properties of Sulfur-Chelated Ruthenium Benzylidenes Bearing a Cyclic (Alkyl)(amino)carbene Ligand
Sulfur-chelated
ruthenium olefin metathesis precatalysts that possess
cyclic (alkyl)(amino)carbenes (CAAC) can benefit from the synergetic
effect of both ligands. Changing the steric bulk of the CAAC ligand
by using different substitution patterns was shown to affect the geometry
of the complexes produced and determined whether the complexes could
be catalytically dormant. The <i>cis</i>-dichloro latent
catalysts could be activated both by heat or light, even in the visible
region, for representative acyclic diene metathesis and ring-opening
metathesis polymerization reactions, olefin cross-metathesis, and
ring-closing metathesis without isomerization byproducts. Thus, these
complexes were shown to combine the uniqueness of CAAC-containing
Ru olefin metathesis catalysts with the advantage of the thermal and
photolatency imposed by sulfur chelation of the benzylidene
Synthesis and Catalytic Properties of Sulfur-Chelated Ruthenium Benzylidenes Bearing a Cyclic (Alkyl)(amino)carbene Ligand
Sulfur-chelated
ruthenium olefin metathesis precatalysts that possess
cyclic (alkyl)(amino)carbenes (CAAC) can benefit from the synergetic
effect of both ligands. Changing the steric bulk of the CAAC ligand
by using different substitution patterns was shown to affect the geometry
of the complexes produced and determined whether the complexes could
be catalytically dormant. The <i>cis</i>-dichloro latent
catalysts could be activated both by heat or light, even in the visible
region, for representative acyclic diene metathesis and ring-opening
metathesis polymerization reactions, olefin cross-metathesis, and
ring-closing metathesis without isomerization byproducts. Thus, these
complexes were shown to combine the uniqueness of CAAC-containing
Ru olefin metathesis catalysts with the advantage of the thermal and
photolatency imposed by sulfur chelation of the benzylidene
Synthesis and Catalytic Properties of Sulfur-Chelated Ruthenium Benzylidenes Bearing a Cyclic (Alkyl)(amino)carbene Ligand
Sulfur-chelated
ruthenium olefin metathesis precatalysts that possess
cyclic (alkyl)(amino)carbenes (CAAC) can benefit from the synergetic
effect of both ligands. Changing the steric bulk of the CAAC ligand
by using different substitution patterns was shown to affect the geometry
of the complexes produced and determined whether the complexes could
be catalytically dormant. The <i>cis</i>-dichloro latent
catalysts could be activated both by heat or light, even in the visible
region, for representative acyclic diene metathesis and ring-opening
metathesis polymerization reactions, olefin cross-metathesis, and
ring-closing metathesis without isomerization byproducts. Thus, these
complexes were shown to combine the uniqueness of CAAC-containing
Ru olefin metathesis catalysts with the advantage of the thermal and
photolatency imposed by sulfur chelation of the benzylidene
Synthesis and Catalytic Properties of Sulfur-Chelated Ruthenium Benzylidenes Bearing a Cyclic (Alkyl)(amino)carbene Ligand
Sulfur-chelated
ruthenium olefin metathesis precatalysts that possess
cyclic (alkyl)(amino)carbenes (CAAC) can benefit from the synergetic
effect of both ligands. Changing the steric bulk of the CAAC ligand
by using different substitution patterns was shown to affect the geometry
of the complexes produced and determined whether the complexes could
be catalytically dormant. The <i>cis</i>-dichloro latent
catalysts could be activated both by heat or light, even in the visible
region, for representative acyclic diene metathesis and ring-opening
metathesis polymerization reactions, olefin cross-metathesis, and
ring-closing metathesis without isomerization byproducts. Thus, these
complexes were shown to combine the uniqueness of CAAC-containing
Ru olefin metathesis catalysts with the advantage of the thermal and
photolatency imposed by sulfur chelation of the benzylidene
Combining a ligand photogenerator and a Ru precatalyst: a photoinduced approach to cross-linked ROMP polymer films
Although metathesis photoinduced catalysis is now well established, there is little development in thin film preparation using photochemically activated ring-opening metathesis polymerization (ROMP). Herein, a N-heterocyclic carbene (NHC) photogenerator (1,3-bis(mesityl)imidazolium tetraphenylborate) is combined with an inactive metathesis catalyst ([RuCl2(p-cymene)]2) to generate under UV irradiation an active catalyst (p-cymene)RuCl2 (NHC), that is capable of producing in a single step cross-linked copolymer films by ROMP of norbornene with dicyclopentadiene. The study shows that the photoinitiated catalytic system can be optimized by increasing the yield of photogenerated NHC through a sensitizer (2-isopropylthioxanthone), and by choosing [RuI2(p-cymene)]2 as precatalyst to provide a long-term photolatency. The cross-linked polymer structure is investigated by a range of techniques including gel content measurement, FT-IR and solid-state 13C NMR spectroscopy, TGA and DSC, which reveal a cross-linking mechanism proceeding through both metathesis and olefin coupling.CATALYTIC SCAFFOLDS BASED ON AMYLOID AGGREGATE