A rolling horizon optimization framework for the simultaneous energy supply and demand planning in microgrids

This work focuses on the development of optimization-based scheduling strategies for the coordination of microgrids. The main novelty of this work is the simultaneous management of energy production and energy demand within a reactive scheduling approach to deal with the presence of uncertainty associated to production and consumption. Delays in the nominal energy demands are allowed under associated penalty costs to tackle flexible and fluctuating demand profiles. In this study, the basic microgrid structure consists of renewable energy systems (photovoltaic panels, wind turbines) and energy storage units. Consequently, a Mixed Integer Linear Programming (MILP) formulation is presented and used within a rolling horizon scheme that periodically updates input data information

Design and Experimental Validation of an Explicit MPC Controller for Regulating Temperature in PEM Fuel Cell Systems

This paper proposes a temperature controller for PEM fuel cell systems with an air blower as thermal circuit. The objective of this controller is to maintain the stack temperature over a given set-point which is obtained from the results of a real-time optimization algorithm with the goal of minimizing the stack degradation and maximizing the global efficiency. An Explicit MPC is proposed to deal with this control problem which presents delays, the critical sampling time, constraints and disturbances. The simulation results show good performance of the controller which accurately tracks the temperature reference over the overall range of operating conditions. Furthermore, the controller is implemented in real-time on a PEM fuel cell test-bench which is installed in the Fuel Cell Laboratory at the University of Seville

Optimization of a network of compressors in parallel: Operational and maintenance planning – The air separation plant case

A general mathematical framework for the optimization of compressors operations in air separation plants that considers operating constraints for compressors, several types of maintenance policies and managerial aspects is presented. The proposed approach can be used in a rolling horizon scheme. The operating status, the power consumption, the startup and the shutdown costs for compressors, the compressor-to-header assignments as well as the outlet mass flow rates for compressed air and distillation products are optimized under full demand satisfaction. The power consumption in the compressors is expressed by regression functions that have been derived using technical and historical data. Several case studies of an industrial air separation plant are solved. The results demonstrate that the simultaneous optimization of maintenance and operational tasks of the compressors favor the generation of better solutions in terms of total costs

Advanced model-based control studies for the induction and maintenance of intravenous anaesthesia

This paper describes strategies toward model-based automation of intravenous anaesthesia employing advanced control techniques. In particular, based on a detailed compartmental mathematical model featuring pharmacokinetic and pharmacodynamics information, two alternative model predictive control strategies are presented: a model predictive control strategy, based on online optimization, the extended predictive self-adaptive control and a multiparametric control strategy based on offline optimization, the multiparametric model predictive control. The multiparametric features to account for the effect of nonlinearity and the impact of estimation are also described. The control strategies are tested on a set of 12 virtually generated patient models for the regulation of the depth of anaesthesia by means of the bispectral index (BIS) using Propofol as the administrated anaesthetic. The simulations show fast response, suitability of dose, and robustness to induce and maintain the desired BIS setpoint

Key environmental stress biomarker candidates for the optimisation of chemotherapy treatment of leukaemia

The impact of fluctuations of environmental parameters such as oxygen and starvation on the evolution of leukaemia is analysed in the current review. These fluctuations may occur within a specific patient (in different organs) or across patients (individual cases of hypoglycaemia and hyperglycaemia). They can be experienced as stress stimuli by the cancerous population, leading to an alteration of cellular growth kinetics, metabolism and further resistance to chemotherapy. Therefore, it is of high importance to elucidate key mechanisms that affect the evolution of leukaemia under stress. Potential stress response mechanisms are discussed in this review. Moreover, appropriate cell biomarker candidates related to the environmental stress response and/or further resistance to chemotherapy are proposed. Quantification of these biomarkers can enable the combination of macroscopic kinetics with microscopic information, which is specific to individual patients and leads to the construction of detailed mathematical models for the optimisation of chemotherapy. Due to their nature, these models will be more accurate and precise (in comparison to available macroscopic/black box models) in the prediction of responses of individual patients to treatment, as they will incorporate microscopic genetic and/or metabolic information which is patient-specific.peer-reviewe