Partisipasi Online Dalam Pembelajaran Community of Inquiry (Coi) Pada Materi Distilasi

Participation of chemistry student State University of Malang in the course of chemical separation is not maximized. It is necessary to apply one student centered learning strategy, that inquiry. Inquiry who form a learners group called the Community of Inquiry (CoI). Face-to-face meeting is a little on the distillation that can not maintain CoI in the classroom so that online learning is applied. The purpose of this study was to determine the online participation through CoI in the distillation. The method used is the pre-experimental with descriptive data analysis. Descriptive analysis states student participation in online learning in the distillation was high.Partisipasi mahasiswa Jurusan Kimia Universitas Negeri Malang dalam matakuliah pemisahan kimia belum maksimal sehingga perlu diterapkan salah satu strategi pembelajaran berpusat pada mahasiswa, yaitu inkuiri. Penerapan inkuiri dapat dilakukan dengan membentuk suatu kelompok mahasiswa yang disebut Community of Inquiry (CoI). Pertemuan tatap muka yang sedikit pada materi distilasi tidak dapat mempertahankan CoI di dalam kelas sehingga dilakukan pembelajaran online. Tujuan penelitian ini adalah mengetahui partisipasi online mahasiswa melalui penerapan pembelajaran CoI pada materi distilasi. Metode penelitian yang digunakan adalah pra-eksperimental dengan analisis data deskriptif. Hasil analisis deskriptif menyatakan partisipasi mahasiswa dalam pembelajaran online pada materi distilasi adalah tinggi

Facility-Based Treatment of Under Five Diarrhoea in Cross River State: A Clinical Audit

Introduction: Diarrhoea is the second leading cause of under-five mortality globally and ranks second among the top 10 priority child health problems in Nigeria. The World Health Organization (WHO) has recommended some cost-effective, evidence- based interventions for diarrhoea case management. It is needful to evaluate the current practice in the treatment of diarrhoea in under-fives in health facilities in the country.Objective: To determine the extent to which current treatment practice for diarrhoea in underfives conforms to the WHO recommendation.Method: A clinical audit was conducted between May and June 2013 in 32 health facilities in the Southern Senatorial district of Cross River State, Nigeria. Trained field workers extracted information from patients’ case records using a validated audit tool. Treatment was checked as appropriate, inappropriate, wrong or none, based on prescription on patients’ case records.Result: Of the 370 case records audited, prescription for diarrhoea was appropriate in 40 (10.8%), inappropriate in 231 (62.4%), wrong in 82 (22.2%) and no prescription was made in 17 (4.6%).Conclusion: Treatment of diarrhoea in under-fives in health facilities in the State is suboptimum. Retraining of health workers on the current WHO and UNICEF treatment guidelines is highly recommended.Keywords: Diarrhoea, Underfives, Health Facilities, Prescription, Clinical Audi

Quality of life of patients with kidney failure in sub-Saharan Africa: protocol for a systematic review of quantitative studies

Introduction: The burden of chronic kidney disease (CKD) is rising in sub-Saharan Africa. Access to kidney replacement therapy (KRT) remains limited and modelling suggests a significant hidden burden of kidney failure managed without KRT. Kidney failure is contributing to serious health-related suffering (SHS) at a global level. Despite this, access to palliative care remains extremely disparate. There is an urgent need for greater palliative care provision for patients with kidney failure in sub-Saharan Africa. To inform this, it is important to understand their current quality of life. This article outlines our review protocol, ensuring transparency of our planned methods and reporting. Methods and analysis: A comprehensive search will be conducted of MEDLINE (Ovid), EMBASE, CINAHL, African Index Medicus and Africa Journals Online. ProQuest Dissertations & Theses Global will be searched for grey literature. Eligible sources will be quantitative observational studies, conducted in sub-Saharan Africa, and published in English or French. The primary outcome measure will be quality of life of those with kidney failure, measured using a validated quality of life tool. Abstract screening, data extraction and risk of bias assessments will be conducted independently by two reviewers. Meta-analysis will be performed on study subgroups, if appropriate, based on heterogeneity of included studies; otherwise results will be summarised narratively. This protocol is structured according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidance. Ethics and dissemination: Ethical approval is not required because this review will synthesise published data. Findings will be disseminated in a peer-reviewed journal. PROSPERO registration ID: 27543

Booster Dose of Bacille Calmette-Guérin Vaccine for Tuberculosis in Low and Middle-Income Countries: A Systematic Review

Background: The Bacille Calmette-Guérin (BCG) vaccine, given as a single dose, offers variable protection against Tuberculosis (TB). It is plausible that repeat doses could improve the effectiveness of the BCG vaccine in settings where the population remain at risk of the disease. Objective: To assess the effectiveness of BCG revaccination as a booster dose in preventing TB in Low- and Middle- Income Countries (LMICs). Methods: We searched the electronic databases without language or publication restrictions and followed the procedures for preparing systematic reviews, including assessing the risk of bias as outlined in the Cochrane handbook. We included randomised controlled trials (RCTs) conducted in LMICs involving children and adults receiving one or more BCG vaccine doses after the primary BCG vaccination. The incidence of severe forms of TB, active TB and adverse events were the primary outcomes. Results: Five RCTs were included in this systematic review. Revaccination with BCG probably makes little or no difference to the risk of active TB measured after five years (Relative risk (RR) 1.16, 95% CI 0.88 to 1.51; 348,083 participants; one study, moderate certainty evidence) or nine years post-revaccination (RR 0.96, 95% CI 0.82 to 1.12; 348,083 participants; one study, moderate certainty evidence). In populations with HIV co-infection, revaccination probably increases the risk of pulmonary tuberculosis compared to placebo (RR 1.74, 95% CI 1.00 to 3.01; 46,764 participants; one study, moderate certainty evidence). Conclusion: The available evidence suggests that BCG revaccination probably makes little or no difference in preventing tuberculosis disease in LMICs

Pharmacy Admissions: The Dating Game

Abstract: Background: According to the American Association of Colleges of Pharmacy, as of July 2015, there are 132 US-based colleges and schools of pharmacy. The decision on which school students choose can be one of the most important decisions they will make in their lives. Many factors can affect these decisions, such as: curricular content, location/facilities, finances, and diversity. Although there are many factors that impact student decisions, the relative importance of these factors is unknown. This project will determine the importance of these factors in order to aid school recruitment. Objectives: The objective of this project is to determine the influence of the following factors on student decisions regarding which school to attend: (1) academic standards, programs, and offerings, (2) ethnic, gender, and cultural diversity of enrolled students, (3) cost and financial aid offerings, (4) prestige, (5) facilities offered, and (6) location of the school. Methods: A cross-sectional study design will be performed by surveying undergraduate and graduate students in schools of pharmacy in each geographic region of the United States, both public and private, as well as to faith-based institutions. The survey, sent via Qualtrics, will obtain demographic information and assess the importance of 6 factors identified in the objectives. The survey will be designed using a review of the literature and undergo expert and peer review. Data will be analyzed in SPSS to determine overall results as well as differences by demographic information using a One Way ANOVA, Chi-Squared test, and Kruskal-Wallis test, as appropriate. An a priori of α=0.05 will e be set for statistical significance. After analysis is complete, educational materials will be created for student recruitment based on important factors identified. Project Significance: This study will provide information for pharmacy schools to improve their recruiting process and target potential students who best fit their program

Microfluidic Microcirculation Mimetic as a Tool for the Study of Rheological Characteristics of Red Blood Cells in Patients with Sickle Cell Anemia

Sickle cell disorder (SCD) is a multisystem disease with heterogeneous phenotypes. Al- though all patients have the mutated hemoglobin (Hb) in the SS phenotype, the severity and frequency of complications are variable. When exposed to low oxygen tension, the Hb molecule becomes dense and forms tactoids, which lead to the peculiar sickled shapes of the affected red blood cells, giving the disorder its name. This sickle cell morphology is responsible for the profound and widespread pathologies associated with this disorder, such as vaso-occlusive crisis (VOC). How much of the clinical manifestation is due to sickled erythrocytes and what is due to the relative contributions of other elements in the blood, especially in the microcapillary circulation, is usually not visualized and quantified for each patient during clinical management. Here, we used a microfluidic microcirculation mimetic (MMM), which has 187 capillary-like constrictions, to impose deformations on erythrocytes of 25 SCD patients, visualizing and characterizing the morpho-rheological properties of the cells in normoxic, hypoxic (using sodium meta-bisulfite) and treatment conditions (using hydroxyurea). The MMM enabled a patient-specific quantification of shape descriptors (circularity and roundness) and transit time through the capillary constrictions, which are readouts for morpho-rheological proper- ties implicated in VOC. Transit times varied significantly (p < 0.001) between patients. Our results demonstrate the feasibility of microfluidics-based monitoring of individual patients for personalized care in the context of SCD complications such as VOC, even in resource-constrained setting

Money supply, interest rate, liquidity and share prices: A test of their linkage

This paper reports new evidence of a liquidity effect on share prices from money supply changes. Money supply impacts on interest rate and liquidity were first proposed in 1969 and there is evidence that money supply increase leads to interest rate decline. Yet the proposition that money supply increase should lead to liquidity surge – thus to credit expansion – has yet received unanimous empirical support. Using quarterly data over 1968-2011, our results from a two-stage simultaneous solution of a system of equations indicate that money supply changes lead to a positive liquidity effect, as per the theory prediction. By extending the liquidity equation to asset prices, we also show that liquidity change has a significant positive effect on share prices, after controlling the effect of earnings. These findings, obtained after solutions to serious econometric issues of existing studies, appear to provide a clear verification of theory on the money supply effect on liquidity and on asset price

Applications and Action Mechanisms of Probiotic-Based Multi-Components

editorial reviewedProbiotic-based multi-component preparations refer to a mixture of bioactive agents, containing probiotics or postbiotics as main functional ingredients, and prebiotics, protectants, stabilizers, encapsulating agents, and other compounds as additional constituents.One Health approaches to support agroecological transformation of peri-urban farming1. No poverty2. Zero hunger3. Good health and well-being10. Reduced inequalities11. Sustainable cities and communities12. Responsible consumption and production13. Climate action17. Partnerships for the goal

Embedded Software of the KM3NeT Central Logic Board

The KM3NeT Collaboration is building and operating two deep sea neutrino telescopes at the bottom of the Mediterranean Sea. The telescopes consist of latices of photomultiplier tubes housed in pressure-resistant glass spheres, called digital optical modules and arranged in vertical detection units. The two main scientific goals are the determination of the neutrino mass ordering and the discovery and observation of high-energy neutrino sources in the Universe. Neutrinos are detected via the Cherenkov light, which is induced by charged particles originated in neutrino interactions. The photomultiplier tubes convert the Cherenkov light into electrical signals that are acquired and timestamped by the acquisition electronics. Each optical module houses the acquisition electronics for collecting and timestamping the photomultiplier signals with one nanosecond accuracy. Once finished, the two telescopes will have installed more than six thousand optical acquisition nodes, completing one of the more complex networks in the world in terms of operation and synchronization. The embedded software running in the acquisition nodes has been designed to provide a framework that will operate with different hardware versions and functionalities. The hardware will not be accessible once in operation, which complicates the embedded software architecture. The embedded software provides a set of tools to facilitate remote manageability of the deployed hardware, including safe reconfiguration of the firmware. This paper presents the architecture and the techniques, methods and implementation of the embedded software running in the acquisition nodes of the KM3NeT neutrino telescopes