Cartography of high-dimensional flows: A visual guide to sections and slices

Symmetry reduction by the method of slices quotients the continuous symmetries of chaotic flows by replacing the original state space by a set of charts, each covering a neighborhood of a dynamically important class of solutions, qualitatively captured by a `template'. Together these charts provide an atlas of the symmetry-reduced `slice' of state space, charting the regions of the manifold explored by the trajectories of interest. Within the slice, relative equilibria reduce to equilibria and relative periodic orbits reduce to periodic orbits. Visualizations of these solutions and their unstable manifolds reveal their interrelations and the role they play in organizing turbulence/chaos.Comment: 12 Pages, 12 figure

Editorial

Presentamos aquí un espacio de discusión y reflexión en torno a los desafíos teóricos, metodológicos y epistemológicos que implican pensar las migraciones contemporáneas. Es un compromiso ético en la producción de conocimiento acercarnos de manera clara a nuevas perspectivas y posibilidades de encuentro y vínculo de las relaciones en escenarios inéditos donde las identificaciones se están erigiendo

Pacifico Agravo e eles: Esta herida llena de peces de Lorena Salazar Masso

Mothers and daughters and sons, the effect of being a mother and the process of becoming one or not being one are widely recognized narratives in literature, film and culture in general. This article traces the Western feminist agendas regarding the experience of motherhood/maternity in order to arrive at the concept of parenthood, to then enter into a dialogue with the novel Esta herida llena de peces (2021) by Colombian writer Lorena Salazar Masso. In it, two mothers who share the same child travel together by river in the midst of a conflict that overwhelms the inhabitants of the Colombian Pacific region, embracing a permanent state of transit and readjustment as the only way to live. Current studies on liminality will serve as the fabric to find those spaces of the novel that link its characters-they/mothers and the Atrato river with the reformulation of social and cultural forces/values. In short, the article tracks those intersections between the experience of parenthood of both mothers and the river as liminal spaces of unceasing transformation.Las narrativas de la maternidad y el proceso de ser o no ser madres son frecuentes en la literatura, en el cine y en la cultura en general. Un breve recorrido por las agendas feministas de Occidente permitirá visualizar la experiencia de la maternidad/maternaje, llegar al concepto de parentalidad y dialogar con la novela Esta herida llena de peces (2021) de Lorena Salazar Masso. Dos madres que comparten un hijo y un viaje por el río en medio de un conflicto que desborda a los habitantes del Pacífico colombiano son el relieve que presenta aquel estado permanente de tránsito y de reajuste. Los estudios sobre la liminalidad constituyen el tejido para encontrar espacios de la novela que vinculan a sus personajes-ellas y al río Atrato, con la reformulación de fuerzas/valores sociales y culturales. Se analizan las intersecciones entre la experiencia de la parentalidad de ambas madres y el río como espacios liminales de transformación continua.As narrativas da  maternidade, o processo de ser ou não  ser mães são frequentes na literatura, no cinema e na cultura em geral. Um breve percurso pelas agendas feministas do Ocidente. Uma  breve incursão pelas agendas feministas ocidentais  permitirá visualizar a experiência da maternidade/maternagem, chegar ao conceito de parentalidade e dialogar com o romance Esta herida llena de peces (2021) da escritora colombiana Lorena Salazar Masso. Duas mães que compartilham o mesmo filho e uma viagem pelo rio em meio a um conflito que assola os habitantes da região do Pacífico  são  o relevo que apresenta o estado permanente de trânsito e de reajuste colombianos. Os estudos sobre a liminaridade constituem o tecido para encontrar espaços do romance que vinculam aos seus personagens-elas e ao rio Atrato, com a reformulação de forças/valores sociais e culturais. São analisadas as interseceções entre a experiencia de la parentalidade de ambas mães e o rio como espaços liminais de transformação continua

Circuitos mediáticos y relato de género en el Medio Oriente durante los años sesenta : el caso de Kuwait.

El siguiente artículo se propone identificar los alcances del discurso mediático en el establecimiento de imaginarios culturales de género dentro del marco de descolonización y modernización de naciones en el Medio Oriente, tomando el caso de Kuwait. A través de una lectura de imágenes de anuncios publicitarios provenientes del periódico Kuwait Times durante la década de los sesenta, se explicará cómo el cambio de los centros de poder en la nueva conformación geopolítica además de dar el impulso histórico a Kuwait para formularse como una nación democrática dio también paso a la mediación informativa, cuya plataforma es la creación de productores y consumidores de información dentro de esta zona. En consecuencia, la democracia y la modernidad interpelaron un diálogo que se refleja en las imágenes del periódico, exponiendo las complejas y múltiples realidades del relato de género en Kuwait en la década de los sesenta y su sucesiva relevancia hoy día

Improved corrosion resistance of commercially pure magnesium after its modification by plasma electrolytic oxidation with organic additives

The optimal mechanical properties render magnesium widely used in industrial and biomedical applications. However, magnesium is highly reactive and unstable in aqueous solutions, which can be modulated to increase stability of reactive metals that include the use of alloys or by altering the surface with coatings. Plasma electrolytic oxidation is an efficient and tuneable method to apply a surface coating. By varying the plasma electrolytic oxidation parameters voltage, current density, time and (additives in the) electrolytic solution, the morphology, composition and surface energy of surface coatings are set. In the present study, we evaluated the influence on surface coatings of two solute additives, i.e. hexamethylenetetramine and mannitol, to base solutes silicate and potassium hydroxide. Results from in vitro studies in NaCl demonstrated an improvement in the corrosion resistance. In addition, coatings were obtained by a two-step anodization procedure, firstly anodizing in an electrolyte solution containing sodium fluoride and secondly in an electrolyte solution with hexamethylenetetramine and mannitol, respectively. Results showed that the first layer acts as a protective layer which improves the corrosion resistance in comparison with the samples with a single anodizing step. In conclusion, these coatings are promising candidates to be used in biomedical applications in particular because the components are non-toxic for the body and the rate of degradation of the surface coating is lower than that of pure magnesium

Centromere-associated repeat arrays on Trypanosoma brucei chromosomes are much more extensive than predicted

BACKGROUND: African trypanosomes belong to a eukaryotic lineage which displays many unusual genetic features. The mechanisms of chromosome segregation in these diploid protozoan parasites are poorly understood. Centromeres in Trypanosoma brucei have been localised to chromosomal regions that contain an array of ~147 bp AT-rich tandem repeats. Initial estimates from the genome sequencing project suggested that these arrays ranged from 2 - 8 kb. In this paper, we show that the centromeric repeat regions are much more extensive. RESULTS: We used a long-range restriction endonuclease mapping approach to more accurately define the sizes of the centromeric repeat arrays on the 8 T. brucei chromosomes where unambiguous assembly data were available. The results indicate that the sizes of the arrays on different chromosomes vary from 20 to 120 kb. In addition, we found instances of length heterogeneity between chromosome homologues. For example, values of 20 and 65 kb were obtained for the arrays on chromosome 1, and 50 and 75 kb for chromosome 5. CONCLUSIONS: Our results show that centromeric repeat arrays on T. brucei chromosomes are more similar in size to those of higher eukaryotes than previously suspected. This information provides a firmer framework for investigating aspects of chromosome segregation and will allow epigenetic features associated with the process to be more accurately mapped

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

PMCID: PMC3544714This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Differentiation and multipotential characteristics of mesenchymal stem cells derived from adipose tissue of an endangered wild cat (Leopardus guigna)

Adipose tissue derived mesenchymal stem cells (AMSCs) had been isolated and used for cell therapy in domestic cats. For wild cats, the isolation of AMSCs has only been reported in the black-footed cat (Felis nigripes). AMSCs obtained from wild cats may be useful to treat injuries of endangered cat species that remain in captivity or arrive at wildlife rehabilitation centers. Additionally, AMSCs might allow improvement of cloning techniques or assist in derivation of induced pluripotent stem cells. Endangered wild cats such as the guigna (Leopardus guigna), an endemic and endangered species from Chile and Argentina, might benefit greatly from the development of novel treatments or techniques that can be applied for its conservation. The objective of this study was to characterise putative AMSCs from guigna in terms of their main biological attributes, particularly, growth kinetics, differentiation ability and surface marker expression. Results obtained from this characterisation were compared with AMSCs isolated from domestic cats. AMSCs were isolated from peritoneal adipose tissue of female cats and subcutaneous tissue from a female guigna. Migration potential, colony-forming unit assay, mesodermal differentiation and surface marker expression (CD45, CD44, CD90, MHCI and MHCII) were evaluated. Domestic cat and guigna AMSCs displayed similar growth properties in culture. Both AMSC types showed mesodermal differentiation potential, in vitro homing potential and similar surface marker expression. These results indicate that AMSCs from subcutaneous tissue of guigna could have potential use as regenerative treatment for this species and might be considered for use in other biotechnological applications

Intermediate monocytes and cytokine production associated with severe forms of chagas disease

Q1Monocytes are classified according to their CD14 and CD16 expression into classical (reparative), intermediate (inflammatory), and non-classical. This study assessed the frequency of monocyte and the relationship between monocyte subset percentages and the levels of blood cytokines in Colombian chagasic patients with different clinical forms. This study included chagasic patients in different clinical stages: indeterminate (IND) n = 14, chronic chagasic cardiomyopathy (CCC) n = 14, and heart transplant chagasic (HTCC) n = 9; controls with non-chagasic cardiopathy (NCC) n = 15, and healthy individuals (HI) n = 15. Peripheral blood mononuclear cells (PBMCs) were isolated, labeled for CD14, CD16, and HLA-DR, and analyzed by flow cytometry. Cytokines were measured with a bead-based immunoassay. Percentages of total CD14+ CD16+ and CD14+ HLA-DR+ monocytes were higher in patients with heart involvement (CCC, HTCC, and NCC) than controls. Percentages of intermediate monocytes increased in symptomatic chagasic patients (CCC and HTCC) compared to asymptomatic chagasic patients (IND) and controls (HI). Asymptomatic chagasic patients (IND) had higher percentages of classical monocytes, an increased production of CCL17 chemokine compared to chagasic symptomatic patients (CCC), and their levels of CCL17 was positively correlated with the percentage of classical monocyte subset. In CCC, the percentages of intermediate and classical monocytes were positively correlated with IL-6 levels, which were higher in this group compared to HI, and negatively with IL-12p40 concentration, respectively. Remarkably, there also was an important increased of classical monocytes frequency in three chronic chagasic patients who underwent cardiac transplant, of which one received anti-parasitic treatment. Our findings suggest that cardiac chagasic patients have an increased percentage of inflammatory monocytes and produce more IL-6, a biomarker of heart failure and left ventricular dysfunction, whereas asymptomatic chagasic individuals present a higher percentage of reparative monocytes and CCL17.N/