A Model Curriculum Integrating Values/Morals Education into Secondary Level Language Arts Instruction

The purpose of the project was to develop a model curriculum integrating values/morals education with language arts instruction. To accomplish this purpose a current literature search regarding values/morals education and related language arts instruction was conducted. Additionally, related information from selected schools was obtained and analyzed

A Study of Knowledge and Practical Skill Performance in University Students: A Comparison of Technology Enriched versus Traditional Classroom Instruction

Context: Technology is increasingly utilized in the delivery of athletic training education. Hand-held technology affords continued education outside the classroom. Purpose: To determine the effect of mobile technology on the acquisition of knowledge and practical skills in a university upper extremity evaluation course. Design and Setting: A cohort retrospective archival assessment in a university office environment of grades and performance on written and practical examinations in an upper extremity evaluation course. Participants: Sixty-four college age participants (male n=35, 54.69%, female n=29, 45.31%) previously enrolled in an undergraduate or graduate athletic training program who completed the upper extremity evaluation course between Spring 2009 and Spring 2012. Main Outcome Measures: Dependent variables included final written examination score, final oral practical examination score, and final grade. The independent variable was the technology-enriched instruction provided using the Flashcards Deluxe application available on Android, Apple iPod Touch, iPhone, or iPad devices. This application allows participants to study electronic flashcards with text, pictures, and sound on a mobile device. The control group did not receive the technology-enriched instruction. Results: A one-way between subjects ANOVA was conducted to compare the effect of technology on final written examination, final oral practical examination, and overall grade. There was a significant effect on the final written examination [F (1,63)= 11.621, p = .001,η²=.158]; however, oral practical examination [F(1,63)=0.348, p=.557,η²=.006] and overall grade [F(1,63)=0.695, p=.408,η²=.011] were not significant. Conclusion: Participants with technology-enriched instruction performed significantly better on their final written examination. Based on the findings, technology-enriched instruction improves a student’s knowledge comprehension of orthopedic principles of evaluation. Student performance was improved on written examinations following the use of electronic flashcards. Based on the findings in this study, technology-enriched instruction improves a student’s comprehension of upper extremity evaluation knowledge. It is reasonable to believe the use of flashcards would assist in student comprehension in other learning areas as well

Sampling Daphnia's expressed genes: preservation, expansion and invention of crustacean genes with reference to insect genomes

<p>Abstract</p> <p>Background</p> <p>Functional and comparative studies of insect genomes have shed light on the complement of genes, which in part, account for shared morphologies, developmental programs and life-histories. Contrasting the gene inventories of insects to those of the nematodes provides insight into the genomic changes responsible for their diversification. However, nematodes have weak relationships to insects, as each belongs to separate animal phyla. A better outgroup to distinguish lineage specific novelties would include other members of Arthropoda. For example, crustaceans are close allies to the insects (together forming Pancrustacea) and their fascinating aquatic lifestyle provides an important comparison for understanding the genetic basis of adaptations to life on land versus life in water.</p> <p>Results</p> <p>This study reports on the first characterization of cDNA libraries and sequences for the model crustacean <it>Daphnia pulex</it>. We analyzed 1,546 ESTs of which 1,414 represent approximately 787 nuclear genes, by measuring their sequence similarities with insect and nematode proteomes. The provisional annotation of genes is supported by expression data from microarray studies described in companion papers. Loci expected to be shared between crustaceans and insects because of their mutual biological features are identified, including genes for reproduction, regulation and cellular processes. We identify genes that are likely derived within Pancrustacea or lost within the nematodes. Moreover, lineage specific gene family expansions are identified, which suggest certain biological demands associated with their ecological setting. In particular, up to seven distinct ferritin loci are found in <it>Daphnia </it>compared to three in most insects. Finally, a substantial fraction of the sampled gene transcripts shares no sequence similarity with those from other arthropods. Genes functioning during development and reproduction are comparatively well conserved between crustaceans and insects. By contrast, genes that were responsive to environmental conditions (metal stress) and not sex-biased included the greatest proportion of genes with no matches to insect proteomes.</p> <p>Conclusion</p> <p>This study along with associated microarray experiments are the initial steps in a coordinated effort by the <it>Daphnia </it>Genomics Consortium to build the necessary genomic platform needed to discover genes that account for the phenotypic diversity within the genus and to gain new insights into crustacean biology. This effort will soon include the first crustacean genome sequence.</p

Benefit-Cost Analysis in Environmental, Health, and Safety Regulation: A Statement of Principles

Benefit-cost analysis can play a very important role in legislative and regulatory policy debates on improving the environment, health, and safety. It can help illustrate the tradeoffs that are inherent in public policymaking as well as make those tradeoffs more transparent. It can also help agencies set regulatory priorities. Benefit-cost analysis should be used to help decisionmakers reach a decision. Contrary to the views of some, benefit-cost analysis is neither necessary nor sufficient for designing sensible public policy. If properly done, it can be very helpful to agencies in the decisionmaking process. Decisionmakers should not be precluded from considering the economic benefits and costs of different policies in the development of regulations. Laws that prohibit costs or other factors from being considered in administrative decisionmaking are inimical to good public policy. Currently, several of the most important regulatory statutes have been interpreted to imply such prohibitions. Benefit-cost analysis should be required for all major regulatory decisions, but agency heads should not be bound by a strict benefit-cost test. Instead, they should be required to consider available benefit-cost analyses and to justify the reasons for their decision in the event that the expected costs of a regulation far exceed the expected benefits. Agencies should be encouraged to use economic analysis to help set regulatory priorities. Economic analyses prepared in support of particularly important decisions should be subjected to peer review both inside and outside government. Benefits and costs of proposed major regulations should be quantified wherever possible. Best estimates should be presented along with a description of the uncertainties. Not all benefits or costs can be easily quantified, much less translated into dollar terms. Nevertheless, even qualitative descriptions of the pros and cons associated with a contemplated action can be helpful. Care should be taken to ensure that quantitative factors do not dominate important qualitative factors in decisionmaking. The Office of Management and Budget, or some other coordinating agency, should establish guidelines that agencies should follow in conducting benefit-cost analyses. Those guidelines should specify default values for the discount rate and certain types of benefits and costs, such as the value of a small reduction in mortality risk. In addition, agencies should present their results using a standard format, which summarizes the key results and highlights major uncertainties.

Is There a Role for Benefit-Cost Analysis in Environmental, Health, and Safety Regulation?

Benefit-cost analysis has a potentially important role to play in helping inform regulatory decision-making, although it should not be the sole basis for such decision-making. This paper offers eight principles on the appropriate use of benefit-cost analysis.Environment, Health and Safety, Regulatory Reform

Z' Coupling Information from the LHeC

If the LHC discovers a $Z'$-like state the extraction of its couplings to the particles of the Standard Model becomes mandatory in order to determine the nature of the underlying new physics theory. It has been well-known for some time that the direct measurements performed at the LHC in the Drell-Yan channel cannot determine these parameters uniquely in a model-independent manner even if large integrated luminosities, $\sim 100 fb^{-1}$, become available and the $Z'$ is relatively light \lsim 1.5 TeV. Here we examine the possibility that a proposed $e_{L,R}^\pm p$ collider upgrade at the LHC, the LHeC, with $\sqrt s=1.5-2$ TeV could be helpful with such coupling determinations in the years before a Linear Collider is constructed. We show that the polarization and charge asymmetries constructed from the cross sections for these processes can be useful in this regard depending upon the specific values of the particular $Z'$ model parameters.Comment: 16 pages, 9 figs, minor modification

Development of in-vessel reflood instrumentation at ORNL. [PWR]

A program under the sponsorship of the United States Nuclear Regulatory Commission was intiated at the Oak Ridge National Laboratory (ORNL) in late 1977. The program, Advanced Instrumentation for Reflood Studies (AIRS), is charged with developing instrumentation for measurement of in-vessel fluid phenomena in pressurized water reactor reflood facilities. The goal of the ORNL program is to develop techniques and systems for measuring fluid flow in-core, deentrainment in the upper plenum and liquid fallback from the upper plenum into the core. A large portion of the development at ORNL is devoted to the impedance probes for measurement of two-phase flow velocities and void fractions. Film probe development at ORNL is limited to adapting the present techniques to the environment of a reflood facility. As the development progresses on all the measurement techniques, ORNL will fabricate and supply instrument systems to the reflood facilities included in the 2D/3D Program

Removal of Magnetic Impurities from Strontium Copper Oxychloride

Analyses of a copper-deficient series of Strontium Copper Oxychloride polycrystalline samples are reported. Magnetic susceptibility, X-ray powder diffraction, and differential thermal analyses show a small Curie-type magnetic signal correlates with =0.6% (excess) copper ions in the nominally stoichiometric material. The analyses also imply that the extra magnetic signal is from an impurity phase, possibly related to Strontium Copper Oxide. The concentration of the impurity phase can be controlled by varying the copper stoichiometry

Search for charge-asymmetric production of W\u27 bosons in tt + jet events from pp collisions at √s = 7 TeV

A search is presented for charge-asymmetric production of a W\u27 boson that has been proposed to accommodate the forward–backward asymmetry observed in the production of top–antitop quark pairs at the Tevatron. The new heavy W\u27 boson would be produced in association with a top quark and would decay into top and down quarks. The data correspond to an integrated luminosity of 5.0 fb−1 in pp collisions at a center-of-mass energy of 7 TeV, recorded by the CMS detector at the LHC. No significant excess above the standard model expectations is observed, and, from a combination of the electron-plusjets and muon-plus-jets channels, a 95% confidence level lower limit of 840 GeV/c2 is set on the W\u27 boson mass for a W\u27 boson model with values for coupling constants to top and down quarks gL = 0 and gR = 2. In addition, a kinematic reconstruction of the W[1] resonance mass using the inherent charge asymmetry of this model finds no indication of the presence of W\u27 events in the data

Phase II study of fosaprepitant + 5HT3 receptor antagonist + dexamethasone in patients with germ cell tumors undergoing 5-day cisplatin-based chemotherapy: A Hoosier Cancer Research Network Study

Purpose A phase III study adding aprepitant to a 5HT3 receptor antagonist (5HT3-RA) plus dexamethasone in germ cell tumor (GCT) patients treated with 5-day cisplatin combination chemotherapy demonstrated a significant improvement in complete response (CR) (J Clin Onc 30:3998-4003, 2012). Fosaprepitant has demonstrated non-inferiority compared to aprepitant in single-day cisplatin chemotherapy and is approved as a single-dose alternative. This single-arm phase II study is the first clinical trial evaluating fosaprepitant in patients receiving multi-day cisplatin regimen. Methods GCT patients receiving a 5-day cisplatin combination chemotherapy were enrolled. Fosaprepitant 150 mg was given IV on days 3 and 5. A 5HT3-RA days 1–5 (days 1, 3, and 5, if palonosetron) plus dexamethasone 20 mg days 1 and 2 and 4 mg po bid days 6, 7, and 8 was administered. Rescue antiemetics were allowed. The primary objective was to determine the CR rate—no emetic episodes or use of rescue medications. Accrual of 64 patients was planned with expected CR > 27 %. Results Sixty-five patients were enrolled of whom 54 were eligible for analysis. Median age was 33. Fifty-one patients received bleomycin, etoposide, and cisplatin (BEP) chemotherapy. CR was observed in 13 (24.1 %) patients (95 % Agresti-Coull binomial C.I. 14.5 %, 37.1 %). Conclusion The data in this phase II study, in contrast to our prior phase III study, appears to indicate a lower CR rate with the substitution of fosaprepitant for aprepitant. It is unknown whether the substitution of fosaprepitant for aprepitant provides the same benefit in multi-day cisplatin that was achieved with single-day cisplatin