7 research outputs found
Evaluation of the Bactericidal Activity of Didecyl Dimethyl Ammonium Chloride in 2-Propanol against Pseudomonas aeruginosa
Antimicrobial activity of Butyl acetate, Ethyl acetate and Isopropyl alcohol on undesirable microorganisms in cosmetic products
Proposed phase 2/ step 2 in-vitro test on basis of EN 14561 for standardised testing of the wound antiseptics PVP-iodine, chlorhexidine digluconate, polihexanide and octenidine dihydrochloride
Specificity of the neutralizers as the cause of errors in evaluating disinfectant efficacy: an assessment of triclosan
Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials
Five oxypropanol amine derivatives that four of them are novel have been synthesized with high yields and
practical methods. in vitro antibacterial susceptibility of Acinetobacter baumannii, Pseudomonas aeruginosa,
Escherichia coli and Staphylococcus aureus strains to synthesized substances were evaluated with agar well-diffusion
method by comparison with commercially available drugs. Most of the bacteria were multidrug resistant.
It was concluded that these compounds are much more effective than reference drugs. These eugenol bearing
oxypropanolamine derivatives were also effective inhibitors against α-glycosidase, cytosolic carbonic anhydrase
I and II isoforms (hCA I and II), and acetylcholinesterase (AChE) enzymes with Ki values in the range
of 0.80 ± 0.24–3.52 ± 1.01 µM for hCA I, 1.08 ± 0.15–3.64 ± 0.92 µM for hCA II, 5.18 ±
0.84–12.46 ± 2.08 µM for α-glycosidase, and 11.33 ± 2.83–32.81 ± 9.73 µM for AChE, respectivel