Vibration stimuli and the differentiation of musculoskeletal progenitor cells: Review of results in vitro and in vivo

Due to the increasing burden on healthcare budgets of musculoskeletal system disease and injury, there is a growing need for safe, effective and simple therapies. Conditions such as osteoporosis severely impact on quality of life and result in hundreds of hours of hospital time and resources. There is growing interest in the use of low magnitude, high frequency vibration (LMHFV) to improve bone structure and muscle performance in a variety of different patient groups. The technique has shown promise in a number of different diseases, but is poorly understood in terms of the mechanism of action. Scientific papers concerning both the in vivo and in vitro use of LMHFV are growing fast, but they cover a wide range of study types, outcomes measured and regimens tested. This paper aims to provide an overview of some effects of LMHFV found during in vivo studies. Furthermore we will review research concerning the effects of vibration on the cellular responses, in particular for cells within the musculoskeletal system. This includes both osteogenesis and adipogenesis, as well as the interaction between MSCs and other cell types within bone tissue

Quantum dot emission from site-controlled ngan/gan micropyramid arrays

InxGa1−xN quantum dots have been fabricated by the selective growth of GaN micropyramid arrays topped with InGaN/GaN quantum wells. The spatially, spectrally, and time-resolved emission properties of these structures were measured using cathodoluminescence hyperspectral imaging and low-temperature microphotoluminescence spectroscopy. The presence of InGaN quantum dots was confirmed directly by the observation of sharp peaks in the emission spectrum at the pyramid apices. These luminescence peaks exhibit decay lifetimes of approximately 0.5 ns, with linewidths down to 650 me

The pion form factor in improved lattice QCD

We calculate the electromagnetic form factor of the pion in lattice gauge theory. The non-perturbatively improved Sheikoleslami-Wohlert lattice action is used together with the O(a) improved current. The form factor is compared to results for other choices for the current and features of the structure of the pion deduced from the 'Bethe-Salpeter wave function' are discussed.Comment: 8 pages, LaTex, 2 figure

Infinitesimals without Logic

We introduce the ring of Fermat reals, an extension of the real field containing nilpotent infinitesimals. The construction takes inspiration from Smooth Infinitesimal Analysis (SIA), but provides a powerful theory of actual infinitesimals without any need of a background in mathematical logic. In particular, on the contrary with respect to SIA, which admits models only in intuitionistic logic, the theory of Fermat reals is consistent with classical logic. We face the problem to decide if the product of powers of nilpotent infinitesimals is zero or not, the identity principle for polynomials, the definition and properties of the total order relation. The construction is highly constructive, and every Fermat real admits a clear and order preserving geometrical representation. Using nilpotent infinitesimals, every smooth functions becomes a polynomial because in Taylor's formulas the rest is now zero. Finally, we present several applications to informal classical calculations used in Physics: now all these calculations become rigorous and, at the same time, formally equal to the informal ones. In particular, an interesting rigorous deduction of the wave equation is given, that clarifies how to formalize the approximations tied with Hook's law using this language of nilpotent infinitesimals.Comment: The first part of the preprint is taken directly form arXiv:0907.1872 The second part is new and contains a list of example

Detection of the Togninia Teleomorph of Phaeoacremonium aleophilum in Australia

Moist incubation of grapevine wood infected with both Phaeoacremonium aleophilum and Phaeomoniella chlamydospora yielded an ascomycete referable to the genus Togninia (Ascomycota, Calosphaeriales). Single ascospore cultures were morphologically identical to Pm. aleophilum. The rDNA ITS sequence of single ascospore isolates was identical to published sequences for the majority of Pm. aleophilum isolates. Comparison with the morphology of other wood staining Togninia species confirms that the teleomorph of Pm. aleophilum is Togninia minima

Canonical Transformations and Path Integral Measures

This paper is a generalization of previous work on the use of classical canonical transformations to evaluate Hamiltonian path integrals for quantum mechanical systems. Relevant aspects of the Hamiltonian path integral and its measure are discussed and used to show that the quantum mechanical version of the classical transformation does not leave the measure of the path integral invariant, instead inducing an anomaly. The relation to operator techniques and ordering problems is discussed, and special attention is paid to incorporation of the initial and final states of the transition element into the boundary conditions of the problem. Classical canonical transformations are developed to render an arbitrary power potential cyclic. The resulting Hamiltonian is analyzed as a quantum system to show its relation to known quantum mechanical results. A perturbative argument is used to suppress ordering related terms in the transformed Hamiltonian in the event that the classical canonical transformation leads to a nonquadratic cyclic Hamiltonian. The associated anomalies are analyzed to yield general methods to evaluate the path integral's prefactor for such systems. The methods are applied to several systems, including linear and quadratic potentials, the velocity-dependent potential, and the time-dependent harmonic oscillator.Comment: 28 pages, LaTe

Mechanism of carrier-induced ferromagnetism in magnetic semiconductors

Taking into account both random impurity distribution and thermal fluctuations of localized spins, we have performed a model calculation for the carrier (hole) state in Ga$_{1-x}$Mn$_x$As by using the coherent potential approximation (CPA). The result reveals that a {\it p}-hole in the band tail of Ga$_{1-x}$Mn$_x$As is not like a free carrier but is rather virtually bounded to impurity sites. The carrier spin strongly couples to the localized {\it d} spins on Mn ions. The hopping of the carrier among Mn sites causes the ferromagnetic ordering of the localized spins through the double-exchange mechanism. The Curie temperature obtained by using conventional parameters agrees well with the experimental result.Comment: 7 pages, 4 figure

Cluster Spin Glass Distribution Functions in La2−x_{2-x}Srx_xCuO4_4

Signatures of the cluster spin glass have been found in a variety of experiments, with an effective onset temperature $T_{on}$ that is frequency dependent. We reanalyze the experimental results and find that they are characterized by a distribution of activation energies, with a nonzero glass transition temperature $T_g(x)<T_{on}$. While the distribution of activation energies is the same, the distribution of weights depends on the process. Remarkably, the weights are essentially doping independent.Comment: 5 pages, 5 ps figure

Electromagnetic vertex function of the pion at T > 0

The matrix element of the electromagnetic current between pion states is calculated in quenched lattice QCD at a temperature of $T = 0.93 T_c$. The nonperturbatively improved Sheikholeslami-Wohlert action is used together with the corresponding ${\cal O}(a)$ improved vector current. The electromagnetic vertex function is extracted for pion masses down to $360 {\rm MeV}$ and momentum transfers $Q^2 \le 2.7 {\rm GeV}^2$.Comment: 17 pages, 8 figure