93 research outputs found
THE INFLUENCE OF COMORBID ENDEMIC GOITER ON THE QUALITY OF LIFE OF PATIENTS WITH GASTROINTESTINAL PATHOLOGY
THE INFLUENCE OF COMORBID ENDEMIC GOITER ON THE QUALITY OF LIFE OF PATIENTS WITH GASTROINTESTINAL PATHOLOGY
The impairment of adaptive mechanisms of functional systems of the body plays an important role in the occurrence of
gastrointestinal diseases. This impairment is caused by unfavorable ecological and radiation conditions, external stress factors, food
containing carcinogens, macro - and microelements deficiency. Technogenic environmental pollution contributes to decrease in the
level of iodine in the body and more severe course of thyroid pathology. Diseases of the digestive and endocrine systems and their
combination will occupy one of the leading places among the existing pathologies according to the forecasts of WHO experts in the
XXI century. Adaptation of the body to various environmental influences is the most important factor in the quality of life. The
relevance of the study was determined by the high incidence of psychological disadaptation, borderline personality disorders and, as
a consequence, decrease in the quality of life in patients with gastrointestinal pathology and hypothyroidism. The article presents the
results of comparative analysis of the quality of life indications of patients with gastric ulcer and / or gastroesophageal reflux
disease in combination with hypothyroidism. The Russian-language analogue of the international questionnaire SF36 was used to
analyze the indicatoions of patients\u27 quality of life. The results of the study will allow to formulate the diagnosis exactly and organize
adequate, comprehensive multidisciplinary treatment
Search for R-Parity Violating Decays of Scalar Fermions at LEP
A search for pair-produced scalar fermions under the assumption that R-parity
is not conserved has been performed using data collected with the OPAL detector
at LEP. The data samples analysed correspond to an integrated luminosity of
about 610 pb-1 collected at centre-of-mass energies of sqrt(s) 189-209 GeV. An
important consequence of R-parity violation is that the lightest supersymmetric
particle is expected to be unstable. Searches of R-parity violating decays of
charged sleptons, sneutrinos and squarks have been performed under the
assumptions that the lightest supersymmetric particle decays promptly and that
only one of the R-parity violating couplings is dominant for each of the decay
modes considered. Such processes would yield final states consisting of
leptons, jets, or both with or without missing energy. No significant
single-like excess of events has been observed with respect to the Standard
Model expectations. Limits on the production cross- section of scalar fermions
in R-parity violating scenarios are obtained. Constraints on the supersymmetric
particle masses are also presented in an R-parity violating framework analogous
to the Constrained Minimal Supersymmetric Standard Model.Comment: 51 pages, 24 figures, Submitted to Eur. Phys. J.
Measurement of the Hadronic Photon Structure Function F_2^gamma at LEP2
The hadronic structure function of the photon F_2^gamma is measured as a
function of Bjorken x and of the factorisation scale Q^2 using data taken by
the OPAL detector at LEP. Previous OPAL measurements of the x dependence of
F_2^gamma are extended to an average Q^2 of 767 GeV^2. The Q^2 evolution of
F_2^gamma is studied for average Q^2 between 11.9 and 1051 GeV^2. As predicted
by QCD, the data show positive scaling violations in F_2^gamma. Several
parameterisations of F_2^gamma are in agreement with the measurements whereas
the quark-parton model prediction fails to describe the data.Comment: 4 pages, 2 figures, to appear in the proceedings of Photon 2001,
Ascona, Switzerlan
Womenâs beliefs about medicines and adherence to pharmacotherapy in pregnancy: Opportunities for community pharmacists?
Background During pregnancy women might weigh benefits of treatment against potential risks to the unborn child. However, non-adherence to necessary treatment can adversely affect both mother and child. To optimize pregnant womenâs beliefs and medication adherence, community pharmacists are ideally positioned to play an important role in primary care. Objective This narrative review aimed to summarize the evidence on 1) pregnant womenâs beliefs, 2) medication adherence in pregnancy, and 3) community pharmacistsâ counselling during pregnancy. Method Three search strategies were used in Medline and Embase to find original studies evaluating womenâs beliefs, medication adherence and community pharmacistsâ counselling during pregnancy. All original descriptive and analytic epidemiological studies performed in Europe, North America and Australia, written in English and published from 2000 onwards were included. Results We included 14 studies reporting on womenâs beliefs, 11 studies on medication adherence and 9 on community pharmacistsâ counselling during pregnancy. Women are more reluctant to use medicines during pregnancy and tend to overestimate the teratogenic risk of medicines. Risk perception varies with type of medicine, level of health literacy, education level and occupation. Furthermore, low medication adherence during pregnancy is common. Finally, limited evidence showed current community pharmacistsâ counselling is insufficient. Barriers hindering pharmacists are insufficient knowledge and limited access to reliable information. Conclusion Concerns about medication use and non-adherence are widespread among pregnant women. Community pharmacistsâ counselling during pregnancy is insufficient. Further education, training and research are required to support community pharmacists in fulfilling all the opportunities they have when counselling pregnant women
Aging and growth parameter from the Piaractus mesopotamicus (pacu) from the CuiabĂĄ river, Mato Grosso, Brazil
Three principles for the progress of immersive technologies in healthcare training and education
The Public Repository of Xenografts enables discovery and randomized phase II-like trials in mice
More than 90% of drugs with preclinical activity fail in human trials, largely due to insufficient efficacy. We hypothesized that adequately powered trials of patient-derived xenografts (PDX) in mice could efficiently define therapeutic activity across heterogeneous tumors. To address this hypothesis, we established a large, publicly available repository of well-characterized leukemia and lymphoma PDXs that undergo orthotopic engraftment, called the Public Repository of Xenografts (PRoXe). PRoXe includes all de-identified information relevant to the primary specimens and the PDXs derived from them. Using this repository, we demonstrate that large studies of acute leukemia PDXs that mimic human randomized clinical trials can characterize drug efficacy and generate transcriptional, functional, and proteomic biomarkers in both treatment-naive and relapsed/refractory disease
Avaliação da estabilidade foto-oxidativa dos óleos de canola e de milho em presença de antioxidantes sintéticos
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