On the methodology for assessing the quality of telemedicine services in the doctor-doctor system

The objective was to develop a system of indicators of telemedicine services in the "doctor – doctor" system in order to improve the quality of the organization of remote interaction between medical organizations in providing medical care using telemedical technologies.Цель работы – разработать систему показателей телемедицинских услуг в системе «врач – врач» с целью повышения качества организации дистанционного взаимодействия между медицинскими организациями при оказании медицинской помощи с применением телемедицинских технологий

Comparison of temperature sensing of the luminescent upconversion and ZnCdS nanoparticles

The luminescence spectra of upconversion nanoparticles (UCNPs) and ZnCdS nanoparticles (ZnCdSNPs) were measured and analyzed in a wide temperature range: from room to human body and further to a hyperthermic temperature resulting in tissue morphology change. The results show that the luminescence signal of UCNPs and ZnCdSNPs placed within the tissue is reasonably good sensitive to temperature change and accompanied by phase transitions of lipid structures of adipose tissue. The most likely that the multiple phase transitions are associated with the different components of fat cells, such as phospholipids of cell membrane and lipids of fat droplets. In the course of fat cell heating, lipids of fat droplet first transit from a crystalline form to a liquid crystal form and then to a liquid form, which is characterized by much less scattering. The results of phase transitions of lipids were observed as the changes in the slope of the temperature dependence of the intensity of luminescence of the film with nanoparticles embedded into tissue. The obtained results confirm a high sensitivity of the luminescent UCNPs and ZnCdSNPs to the temperature variations within thin tissue samples and show a strong potential for the controllable tissue thermolysis

FEATURES OF TARGETED ADVERTISING IN RUSSIA AFTER THE INTRODUCTION OF SANCTIONS

В данной статье анализируется использование таргетированной рекламы в России после введения санкций в 2022 году. Проведен социальный опрос о наиболее популярных социальных сетях. Сравнение российского постсанкционного рынка таргетированной рекламы с рынком Китая.This article analyzes the use of targeted advertising in Russia after the introduction of sanctions in 2022. A social survey was conducted on the most used social networks. Comparison of the Russian post-sanctions targeted advertising market with the market of China

Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports

Lineage switch is a rare phenomenon in which a transition from lymphoid to myeloid was observed in relapse of acute leukemia, or vice versa. This paper presents the four clinical case reports of acute lymphoblastic leukemia with MLL gene rearrangement (KMT2A) with myeloid phenotype in relapse