On the relationship between standard intersection cuts, lift-and-project cuts, and generalized intersection cuts

We examine the connections between the classes of cuts in the title. We show that lift-and-project (L&P) cuts from a given disjunction are equivalent to generalized intersection cuts from the family of polyhedra obtained by taking positive combinations of the complements of the inequalities of each term of the disjunction. While L&P cuts from split disjunctions are known to be equivalent to standard intersection cuts (SICs) from the strip obtained by complementing the terms of the split, we show that L&P cuts from more general disjunctions may not be equivalent to any SIC. In particular, we give easily verifiable necessary and sufficient conditions for a L&P cut from a given disjunction D to be equivalent to a SIC from the polyhedral counterpart of D. Irregular L&P cuts, i.e. those that violate these conditions, have interesting properties. For instance, unlike the regular ones, they may cut off part of the corner polyhedron associated with the LP solution from which they are derived. Furthermore, they are not exceptional: their frequency exceeds that of regular cuts. A numerical example illustrates some of the above properties. © 2016 Springer-Verlag Berlin Heidelberg and Mathematical Optimization Societ

PARISROC, a Photomultiplier Array Integrated Read Out Chip

PARISROC is a complete read out chip, in AMS SiGe 0.35 !m technology, for photomultipliers array. It allows triggerless acquisition for next generation neutrino experiments and it belongs to an R&D program funded by the French national agency for research (ANR) called PMm2: ?Innovative electronics for photodetectors array used in High Energy Physics and Astroparticles? (ref.ANR-06-BLAN-0186). The ASIC (Application Specific Integrated Circuit) integrates 16 independent and auto triggered channels with variable gain and provides charge and time measurement by a Wilkinson ADC (Analog to Digital Converter) and a 24-bit Counter. The charge measurement should be performed from 1 up to 300 photo- electrons (p.e.) with a good linearity. The time measurement allowed to a coarse time with a 24-bit counter at 10 MHz and a fine time on a 100ns ramp to achieve a resolution of 1 ns. The ASIC sends out only the relevant data through network cables to the central data storage. This paper describes the front-end electronics ASIC called PARISROC.Comment: IEEE Nuclear Science Symposium an Medical Imaging Conference (2009 NSS/MIC

Stable Control of Pulse Speed in Parametric Three-Wave Solitons

We analyze the control of the propagation speed of three wave packets interacting in a medium with quadratic nonlinearity and dispersion. We found analytical expressions for mutually trapped pulses with a common velocity in the form of a three-parameter family of solutions of the three-wave resonant interaction. The stability of these novel parametric solitons is simply related to the value of their common group velocity

La miomectomia laparoscopica: nostra esperienza

I miomi uterini rappresentano la più comune neoplasia benigna della sfera genitale femminile, con una incidenza del 20-25% ed incremento nel periodo premenopausale fino al 50%. Il trattamento può essere medico e/o chirurgico, conservativo o demolitore. La miomectomia laparoscopica consente un approccio il meno traumatico possibile, con ottimi risultati in termini di efficacia della risoluzione della sintomatologia; di ottimizzazione della fertilità; di riduzione dei costi di degenza, in quanto non comporta l’attesa della canalizzazione nel postoperatorio, riduce significativamente la perdita di sangue e consente un rapido ritorno all’attività lavorativa

Integrated optical frequency comb for 5G NR Xhauls

: We experimentally demonstrate the use of optical frequency combs (OFCs), generated by a photonic integrated circuit (PIC), in a flexible optical distribution network based on fiber-optics and free-space optics (FSOs) links, aimed at the fifth generation of mobile network (5G) Xhauls. The Indium Phosphide (InP) monolithically integrated OFC is based on cascaded optical modulators and is broadly tunable in terms of operating wavelength and frequency spacing. Particularly, our approach relies on applying the PIC in a centralized radio access network (C-RAN) architecture, with the purpose of optically generating two low-phase noise mm-waves signals for simultaneously enabling a 12.5-km of single-mode fiber (SMF) fronthaul and a 12.5-km SMF midhaul, followed by a 10-m long FSO fronthaul link. Moreover, the demonstrator contemplates two 10-m reach 5G wireless access networks operating in the 26 GHz band, i.e. over the frequency range 2 (FR2) from the 5G NR standard. The proposed integrated OFC-based 5G system performance is in accordance to the 3rd Generation Partnership Project (3GPP) Release 15 requirements, achieving a total wireless throughput of 900 Mbit/s

Euclid: Superluminous supernovae in the Deep Survey

Context. In the last decade, astronomers have found a new type of supernova called superluminous supernovae (SLSNe) due to their high peak luminosity and long light-curves. These hydrogen-free explosions (SLSNe-I) can be seen to z ~ 4 and therefore, offer the possibility of probing the distant Universe. Aims. We aim to investigate the possibility of detecting SLSNe-I using ESA’s Euclid satellite, scheduled for launch in 2020. In particular, we study the Euclid Deep Survey (EDS) which will provide a unique combination of area, depth and cadence over the mission. Methods. We estimated the redshift distribution of Euclid SLSNe-I using the latest information on their rates and spectral energy distribution, as well as known Euclid instrument and survey parameters, including the cadence and depth of the EDS. To estimate the uncertainties, we calculated their distribution with two different set-ups, namely optimistic and pessimistic, adopting different star formation densities and rates. We also applied a standardization method to the peak magnitudes to create a simulated Hubble diagram to explore possible cosmological constraints. Results. We show that Euclid should detect approximately 140 high-quality SLSNe-I to z ~ 3.5 over the first five years of the mission (with an additional 70 if we lower our photometric classification criteria). This sample could revolutionize the study of SLSNe-I at z > 1 and open up their use as probes of star-formation rates, galaxy populations, the interstellar and intergalactic medium. In addition, a sample of such SLSNe-I could improve constraints on a time-dependent dark energy equation-of-state, namely w(a), when combined with local SLSNe-I and the expected SN Ia sample from the Dark Energy Survey. Conclusions. We show that Euclid will observe hundreds of SLSNe-I for free. These luminous transients will be in the Euclid data-stream and we should prepare now to identify them as they offer a new probe of the high-redshift Universe for both astrophysics and cosmology.Acknowledgements. We thank the internal EC referees (P. Nugent and J. Brichmann) as well as the many comments from our EC colleagues and friends. C.I. thanks Chris Frohmaier and Szymon Prajs for useful discussions about supernova rates. C.I. and R.C.N. thank Mark Cropper for helpful information about the V IS instrument. C.I. thanks the organisers and participants of the Munich Institute for Astro- and Particle Physics (MIAPP) workshop “Superluminous supernovae in the next decade” for stimulating discussions and the provided online material. The Euclid Consortium acknowledges the European Space Agency and the support of a number of agencies and institutes that have supported the development of Euclid. A detailed complete list is available on the Euclid web site (http://www.euclid-ec.org). In particular the Agenzia Spaziale Italiana, the Centre National dEtudes Spatiales, the Deutsches Zentrum für Luft- and Raumfahrt, the Danish Space Research Institute, the Fundação para a Ciênca e a Tecnologia, the Ministerio de Economia y Competitividad, the National Aeronautics and Space Administration, The Netherlandse Onderzoekschool Voor Astronomie, the Norvegian Space Center, the Romanian Space Agency, the State Secretariat for Education, Research and Innovation (SERI) at the Swiss Space Office (SSO), the United Kingdom Space Agency, and the University of Helsinki. R.C.N. acknowledges partial support from the UK Space Agency. D.S. acknowledges the Faculty of Technology of the University of Portsmouth for support during his PhD studies. C.I. and S.J.S. acknowledge funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement No. [291222]. C.I. and M.S. acknowledge support from EU/FP7-ERC grant No. [615929]. E.C. acknowledge financial contribution from the agreement ASI/INAF/I/023/12/0. The work by KJ and others at MPIA on NISP was supported by the Deutsches Zentrum für Luft- und Raumfahrt e.V. (DLR) under grant 50QE1202. M.B. and S.C. acknowledge financial contribution from the agreement ASI/INAF I/023/12/1. R.T. acknowledges funding from the Spanish Ministerio de Economía y Competitividad under the grant ESP2015-69020-C2- 2-R. I.T. acknowledges support from Fundação para a Ciência e a Tecnologia (FCT) through the research grant UID/FIS/04434/2013 and IF/01518/2014. J.R. was supported by JPL, which is run under a contract for NASA by Caltech and by NASA ROSES grant 12-EUCLID12-0004

Different vimentin expression in two clones derived from a human colocarcinoma cell line (LoVo) showing different sensitivity to doxorubicin.

We selected two clones, isolated from the human colocarcinoma cell line LoVo, showing a sensitivity to doxorubicin similar to (LoVo clone 5) or three times lower than (LoVo clone 7) the parental cell line. Since vimentin was atypically expressed in a human breast carcinoma cell line made resistant to doxorubicin, we looked at vimentin expression in these two clones with spontaneously different sensitivity to the drug. For comparison we used the parental cell line LoVo WT and LoVo/DX made resistant pharmacologically. mRNA for vimentin was undetectable by Northern blot analysis in LoVo WT and in LoVo clone 5, while expression of this gene was high in LoVo clone 7 and in LoVo/DX. This increase in mRNA levels was not related to an amplification of DNA, as suggested by Southern blot analysis. Immunofluorescence and immunocytochemistry findings confirmed, at protein level, the mRNA data. In LoVo clones 5 and 7, there were respectively 8.6% and 71% vimentin-positive cells, although the two clones showed similar expression of multidrug resistance gene 1 (mdr-1) and accumulated intracellular doxorubicin at similar levels. Similarly, drug efflux was the same for both clones. Our results show for the first time that cells resistant to doxorubicin express vimentin independently of the mdr glycoprotein. However when cells from clone 5 were transfected with human vimentin cDNA, they did not become resistant, indicating that vimentin can be considered as a marker of resistance in these cells but does not give rise to a resistant phenotype by itself

Distinctive physiological muscle synergy patterns define the Box and Block Task execution as revealed by electromyographic features

Stroke survivors experience muscular pattern alterations of the upper limb that decrease their ability to perform daily-living activities. The Box and Block test (BBT) is widely used to assess the unilateral manual dexterity. Although BBT provides insights into functional performance, it returns limited information about the mechanisms contributing to the impaired movement. This study aims at exploring the BBT by means of muscle synergies analysis during the execution of BBT in a sample of 12 healthy participants with their dominant and non-dominant upper limb. Results revealed that: (i) the BBT can be described by 1 or 2 synergies; the number of synergies (ii) does not differ between dominant and non-dominant sides and (iii) varies considering each phase of the task; (iv) the transfer phase requires more synergies. Clinical Relevance— This preliminary study characterizes muscular synergies during the BBT task in order to establish normative patterns that could assist in understanding the neuromuscular demands and support future evaluations of stroke deficit

Realizability of Polytopes as a Low Rank Matrix Completion Problem

This article gives necessary and sufficient conditions for a relation to be the containment relation between the facets and vertices of a polytope. Also given here, are a set of matrices parameterizing the linear moduli space and another set parameterizing the projective moduli space of a combinatorial polytope