629 research outputs found
Classification of phase transitions in small systems
We present a classification scheme for phase transitions in finite systems
like atomic and molecular clusters based on the Lee-Yang zeros in the complex
temperature plane. In the limit of infinite particle numbers the scheme reduces
to the Ehrenfest definition of phase transitions and gives the right critical
indices. We apply this classification scheme to Bose-Einstein condensates in a
harmonic trap as an example of a higher order phase transitions in a finite
system and to small Ar clusters.Comment: 12 pages, 4 figures, accepted for publication in Phys. Rev. Let
Deceptive signals of phase transitions in small magnetic clusters
We present an analysis of the thermodynamic properties of small transition
metal clusters and show how the commonly used indicators of phase transitions
like peaks in the specific heat or magnetic susceptibility can lead to
deceptive interpretations of the underlying physics. The analysis of the
distribution of zeros of the canonical partition function in the whole complex
temperature plane reveals the nature of the transition. We show that signals in
the magnetic susceptibility at positive temperatures have their origin at zeros
lying at negative temperatures.Comment: 4 pages, 5 figures, revtex4, for further information see
http://www.smallsystems.d
Fractionation of sulfur isotopes during heterogeneous oxidation of SO<sub>2</sub> on sea salt aerosol: a new tool to investigate non-sea salt sulfate production in the marine boundary layer
The oxidation of SO<sub>2</sub> to sulfate on sea salt aerosols in the marine environment is highly important because of its effect on the size distribution of sulfate and the potential for new particle nucleation from H<sub>2</sub>SO<sub>4</sub> (g). However, models of the sulfur cycle are not currently able to account for the complex relationship between particle size, alkalinity, oxidation pathway and rate – which is critical as SO<sub>2</sub> oxidation by O<sub>3</sub> and Cl catalysis are limited by aerosol alkalinity, whereas oxidation by hypohalous acids and transition metal ions can continue at low pH once alkalinity is titrated. We have measured <sup>34</sup>S/<sup>32</sup>S fractionation factors for SO<sub>2</sub> oxidation in sea salt, pure water and NaOCl aerosol, as well as the pH dependency of fractionation. <br><br> Oxidation of SO<sub>2</sub> by NaOCl aerosol was extremely efficient, with a reactive uptake coefficient of ≈0.5, and produced sulfate that was enriched in <sup>32</sup>S with α<sub>OCl</sub> = 0.9882±0.0036 at 19 °C. Oxidation on sea salt aerosol was much less efficient than on NaOCl aerosol, suggesting alkalinity was already exhausted on the short timescale of the experiments. Measurements at pH = 2.1 and 7.2 were used to calculate fractionation factors for each step from SO<sub>2</sub>(g) → multiple steps → SO<sub>OCl</sub><sup>2−</sup>. Oxidation on sea salt aerosol resulted in a lower fractionation factor than expected for oxidation of SO<sub>3</sub><sup>2−</sup> by O<sub>3</sub> (α<sub>seasalt</sub> = 1.0124±0.0017 at 19 °C). Comparison of the lower fractionation during oxidation on sea salt aerosol to the fractionation factor for high pH oxidation shows HOCl contributed 29% of S(IV) oxidation on sea salt in the short experimental timescale, highlighting the potential importance of hypohalous acids in the marine environment. <br><br> The sulfur isotope fractionation factors measured in this study allow differentiation between the alkalinity-limited pathways – oxidation by O<sub>3</sub> and by Cl catalysis (α<sub>34</sub> = 1.0163±0.0018 at 19 °C in pure water or 1.0199±0.0024 at pH = 7.2) – which favour the heavy isotope, and the alkalinity non-limited pathways – oxidation by transition metal catalysis (α<sub>34</sub> = 0.9905±0.0031 at 19 °C, Harris et al., 2012a) and by hypohalites (α<sub>34</sub> = 0.9882±0.0036 at 19 °C) – which favour the light isotope. In combination with field measurements of the oxygen and sulfur isotopic composition of SO<sub>2</sub> and sulfate, the fractionation factors presented in this paper may be capable of constraining the relative importance of different oxidation pathways in the marine boundary layer
Classification of phase transitions of finite Bose-Einstein condensates in power law traps by Fisher zeros
We present a detailed description of a classification scheme for phase
transitions in finite systems based on the distribution of Fisher zeros of the
canonical partition function in the complex temperature plane. We apply this
scheme to finite Bose-systems in power law traps within a semi-analytic
approach with a continuous one-particle density of states for different values of and to a three dimensional harmonically
confined ideal Bose-gas with discrete energy levels. Our results indicate that
the order of the Bose-Einstein condensation phase transition sensitively
depends on the confining potential.Comment: 7 pages, 9 eps-figures, For recent information on physics of small
systems see "http://www.smallsystems.de
Effects of Artesunate on Parasite Recrudescence and Dormancy in the Rodent Malaria Model Plasmodium vinckei
Artemisinin (ART) is the recommended first line therapy for treating uncomplicated and drug-resistant Plasmodium falciparum, the most pathogenic form of malaria. However, treatment failure following ART monotherapy is not uncommon and resistance to this rapidly acting drug has been reported in the Thai-Cambodian border. Recent in vitro studies have shown that following treatment with dihydroartemisinin (DHA), the development of ring-stage parasites is arrested for up to 20 days. These arrested (i.e. dormant) rings could be responsible for the recrudescence of infection that is observed following ART monotherapy. To develop a better understanding of the stage-specific effects of ART and determine if dormancy occurs in vivo, the ART derivative artesunate (AS) was used to treat mice infected with the synchronous rodent malaria parasites P. vinckei petteri (non-lethal) and P. v. vinckei (lethal). Results show that in both the non-lethal and lethal strains, ring-stage parasites are the least susceptible to treatment with AS and that the day of treatment has more of an impact on recrudescence than the total dose administered. Additionally, 24 hrs post-treatment with AS, dormant forms similar in morphology to those seen in vitro were observed. Finally, rate of recrudescence studies suggest that there is a positive correlation between the number of dormant parasites present and when recrudescence occurs in the vertebrate host. Collectively, these data suggest that dormancy occurs in vivo and contributes to recrudescence that is observed following AS treatment. It is possible that this may represent a novel mechanism of parasite survival following treatment with AS
Plasmodium falciparum variant erythrocyte surface antigens: a pilot study of antibody acquisition in recurrent natural infections.
BACKGROUND: During intra-erythrocytic replication Plasmodium falciparum escapes the human host immune system by switching expression of variant surface antigens (VSA). Piecemeal acquisition of variant specific antibody responses to these antigens as a result of exposure to multiple re-infections has been proposed to play a role in acquisition of naturally acquired immunity. METHODS: Immunofluorescence was used to explore the dynamics of anti-VSA IgG responses generated by children to (i) primary malaria episodes and (ii) recurrent P. falciparum infections. RESULTS: Consistent with previous studies on anti-VSA responses, sera from each child taken at the time of recovery from their respective primary infection tended to recognize their own secondary parasites poorly. Additionally, compared to patients with reinfections by parasites of new merozoite surface protein 2 (MSP2) genotypes, baseline sera sampled from patients with persistent infections (recrudescence) tended to have higher recognition of heterologous parasites. This is consistent with the prediction that anti-VSA IgG responses may play a role in promoting chronic asymptomatic infections. CONCLUSIONS: This pilot study validates the utility of recurrent natural malaria infections as a functional readout for examining the incremental acquisition of immunity to malaria
3D Geometric Analysis of Tubular Objects based on Surface Normal Accumulation
This paper proposes a simple and efficient method for the reconstruction and
extraction of geometric parameters from 3D tubular objects. Our method
constructs an image that accumulates surface normal information, then peaks
within this image are located by tracking. Finally, the positions of these are
optimized to lie precisely on the tubular shape centerline. This method is very
versatile, and is able to process various input data types like full or partial
mesh acquired from 3D laser scans, 3D height map or discrete volumetric images.
The proposed algorithm is simple to implement, contains few parameters and can
be computed in linear time with respect to the number of surface faces. Since
the extracted tube centerline is accurate, we are able to decompose the tube
into rectilinear parts and torus-like parts. This is done with a new linear
time 3D torus detection algorithm, which follows the same principle of a
previous work on 2D arc circle recognition. Detailed experiments show the
versatility, accuracy and robustness of our new method.Comment: in 18th International Conference on Image Analysis and Processing,
Sep 2015, Genova, Italy. 201
Impact of deep convection in the tropical tropopause layer in West Africa: in-situ observations and mesoscale modelling
Borrmann Effect in Photonic Crystals: Nonlinear Optical Consequences
Nonlinear-optical manifestations of the Borrmann effect that are consequences
of the spectral dependence of the spatial distributions of the electromagnetic
field in a structure are observed in one-dimensional photonic crystals. The
spectrum of the light self-focusing effect corresponding to the
propagation-matrix calculations has been measured near the edge of the photonic
gap.Comment: 4 pages, 3 figures, published in russian at Pis'ma v Zhurnal
Eksperimental'noi i Teoreticheskoi Fiziki, 2008, Vol. 87, No. 8, pp. 461-46
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