Marketing mix for e-commerce

The relevance of the analyzed issue is caused by the need to study the process of transformation of marketing in e-commerce, as the active involvement of business organizations in the field of e-business is often accompanied by problems of applying the usual marketing tools in a virtual environment. The article seeks to identify changes in the elements of the marketing mix in e-commerce in accordance with the trend of e-business and Internet technology. The leading approach to the study of this issue is the marketing model 7P, allowing structuring the changes in a complex of marketing tools with regard to trade and information services of online stores. The results of research were: to establish the determining role of technology and information support of consumers; to identify the areas of transformation of the marketing mix in e-commerce, demonstrating the significant influence of consumers on the content of 7P and personalize the supply of goods and services. The article may be useful for online stores in case of marketing strategy development, identification of the most important elements of 7P, assessment of marketing effectiveness and optimization of marketing costs. © 2016 Pogorelova et al

Image of Muslim women represented by means of modern English

The aim of the study is to show the image of Muslim women and to identify their position at the language leve

Changes of the colon and rational choice of drug for treatment of chronic constipation in senile patients

Aim of investigation. Clinical and endoscopical investigation of the large intestine in patients of senile age with chronic constipation and estimation of rational treatment.Material and methods. Overall 287 senile patients with chronic constipation were included in original study (mean age 79±2,7). Complex investigation included videocolonoscopy and choosing of drug for rational therapy.Results. It was revealed, that digestive and endocrine diseases are most common in this group of patients. At endoscopic investigation diverticulosis and polyposis coli were the most frequent findings. All patients have tolerated investigation well, no complications have developed. Restoration of regular defecations on a background of lactulose (Duphalac) intake was accompanied by disappearance of feeling of incomplete defecation and necessity of intensive straining effort at defecation.Conclusions. In senile patients chronic constipation is widespread functional disorder, which does not exclude, however, endoscopic control. The age of the patient is not a limiting factor for colonoscopy. Lactulose (Duphalac) is an optimal pharmaceutical with high efficacy

INVESTIGATION OF THE PROPERTIES OF COMPOSITES BASED ON ALUMINUM ALLOY, OBTAINED BY MODIFICATION WITH NANOPOWDER PSEUDOLIGATURES Si3N4, ALN

Работа заключалась в исследовании свойств дисперсно-упрочненных композиционных материалов на основе алюминия. В качестве дисперсных частиц применяется нитрид кремния Si3N4 и нитрид алюминия AlN размером частиц 150 нанометров. Слитки, полученные в результате модифицирования, подвергались микроисследованию, исследованию на твердость и испытанию на разрыв. Результаты, полученные в ходе механических испытаний, а также микроструктуры образцов представлены в работе и свидетельствуют об упрочнении исходного сплава.The work consisted in investigating the properties of dispersion-hardened composite materials based on aluminum. Silicon nitride Si3N4 and AlN aluminum nitride with a particle size of 150 nanometers are used as dispersed articles. The ingots obtained as a result of the modification were subjected to microanalysis, hardness and tensile testing. The results obtained in the course of mechanical tests, as well as the microstructure of the samples are presented in the work and indicate the hardening of the initial alloy

Эффективность иммуномодулирующей терапии внебольничной пневмонии у часто болеющих детей

The aim of the work is to study the indicators of local and systemic immunity in frequently ill children with community-acquired therapy to improve the methods of therapy. 55 children with community-acquired pneumonia and recurrent respiratory diseases (8 or more per year) aged from 3 to 7 years were examined. In the main group (n = 30), on the background of standard therapy, the children received the immunomodulator azoximerе bromide. In the comparison group (n = 25), the children received conventional therapy. Assessment of the state of systemic and mucosal immunity was carried out in dynamics before treatment and after therapy. It was shown that the inclusion of azoxymere bromide leads to an optimal correction of cellular immunity, phagocytic activity of neutrophils, as well as systemic and local cytokine profile. Clinical efficacy is manifested by a reduction in the duration of the febrile period, more rapid relief of intoxication syndromes, respiratory and local pulmonary changes.Цель работы — изучение показателей местного и системного иммунитета у часто болеющих детей с внебольничной пневмонией для совершенствования методов терапии. Обследовано 55 детей с внебольничной пневмонией и рекуррентными респираторными заболеваниями (8 и более в год) в возрасте от 3 до 7 лет жизни. В основной группе (n = 30) на фоне стандартной терапии дети получали иммуномодулятор азоксимера бромид (Полиоксидоний). В группе сравнения (n = 25) дети получали традиционную терапию. Оценка состояния системного и мукозального иммунитета проводилась в динамике до и после лечения. Показано, что включение в терапию внебольничной пневмонии у детей азоксимера бромида приводит к оптимальной коррекции показателей клеточного иммунитета, фагоцитарной активности нейтрофилов, а также системного и локального цитокинового профиля. Клиническая эффективность препарата проявляется сокращением длительности лихорадочного периода и интоксикации, более быстром купировании респираторных и локальных легочных изменений

First CNGS events detected by LVD

The CERN Neutrino to Gran Sasso (CNGS) project aims to produce a high energy, wide band $\nu_{\mu}$ beam at CERN and send it toward the INFN Gran Sasso National Laboratory (LNGS), 732 km away. Its main goal is the observation of the $\nu_{\tau}$ appearance, through neutrino flavour oscillation. The beam started its operation in August 2006 for about 12 days: a total amount of $7.6~10^{17}$ protons were delivered to the target. The LVD detector, installed in hall A of the LNGS and mainly dedicated to the study of supernova neutrinos, was fully operating during the whole CNGS running time. A total number of 569 events were detected in coincidence with the beam spill time. This is in good agreement with the expected number of events from Montecarlo simulations.Comment: Accepted for publication by the European Physical Journal C ; 7 pages, 11 figure

On-line recognition of supernova neutrino bursts in the LVD detector

In this paper we show the capabilities of the Large Volume Detector (INFN Gran Sasso National Laboratory) to identify a neutrino burst associated to a supernova explosion, in the absence of an "external trigger", e.g., an optical observation. We describe how the detector trigger and event selection have been optimized for this purpose, and we detail the algorithm used for the on-line burst recognition. The on-line sensitivity of the detector is defined and discussed in terms of supernova distance and electron anti-neutrino intensity at the source.Comment: Accepted for pubblication on Astroparticle Physics. 13 pages, 10 figure

The treatment of acute corneal hydrops by subtotal penetrating keratoplasty. Clinical case

Clinical case of acute hydrops treatment using subtotal penetrating keratoplasty (PK) is presented. The diagnosis of acute hydrops was based on clinical and functional evaluations including optical coherent tomography (OCT). A part of diseased cornea was removed and examined under a light microscope. These studies revealed morphological changes in almost all corneal layers. OCT and histology demonstrated that PK was indicated to this patient. Recent literature data on the epidemiology and pathogenesis of acute hydrops are presented. This rare disease results from tears in the Descemet’s membrane that allow aqueous humor to enter the stroma. Current treatment is aimed to suppress corneal inflammation, restore endothelium and Descemet’s membrane integrity and drain stromal cysts to optimize cornea healing. In this case, subtotal PK was performed due to the significant corneal thinning and a high risk of its melting. «Material for corneal graft» (iLab, Moscow, Russia) was used as a donor material

Prevalence of risk factors of HIV contamination in injection drug using women in the Omsk Region

The results of an epidemiological study of risk factors of HIV infection among women, who inject drugs, are presented in this paper. Incidence of HIV among women during the period from 2005 to 2013 had a significant increasing trend from 2,1 to 63,3 per 100000 women. The predominance of parenteral transmission of HIV, as well as a significant prevalence of substance abuse disorders among women, determined a significant risk of morbidity for women with HIV infection (6,3 per 10,000 women). We included 115 women, taking injection drugs, in our study. Most of the women noted patterns of high risk HIV infection behavior, as well as the lack of knowledge about HIV prevention. 45% of women had been using drugs for 6-11 years, most of them have started using drugs at the age of 16-19 years, 40% of participants have used more than one type of drug, used common needles, syringes, together with other persons, including those with HIV infection. 23,8% of the women mentioned having unprotected sex, including sex with casual sex partners

Searching for New Physics Through AMO Precision Measurements

We briefly review recent experiments in atomic, molecular, and optical physics using precision measurements to search for physics beyond the Standard Model. We consider three main categories of experiments: searches for changes in fundamental constants, measurements of the anomalous magnetic moment of the electron, and searches for an electric dipole moment of the electron.Comment: Prepared for Comments on AMO Physics at Physica Script